5 Supplementary Figures from Genomic and Expression Profiling of Chromosome 17 in Breast Cancer Reveals Complex Patterns of Alterations and Novel Candidate Genes

Autor: Charles Theillet, Carmen Rodriguez, Stanislas du Manoir, Richard Redon, Catherine Nguyen, Lisa Ursule, Paul Chuchana, Laurence Lasorsa, Nathalie Cervera, Mélanie Nugoli, Béatrice Orsetti

5 Supplementary Figures from Genomic and Expression Profiling of Chromosome 17 in Breast Cancer Reveals Complex Patterns of Alterations and Novel Candidate Genes

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::841030f2be7839d404ab5222e4f4842e
https://doi.org/10.1158/0008-5472.22363341

Data from Genomic and Expression Profiling of Chromosome 17 in Breast Cancer Reveals Complex Patterns of Alterations and Novel Candidate Genes

Autor: Charles Theillet, Carmen Rodriguez, Stanislas du Manoir, Richard Redon, Catherine Nguyen, Lisa Ursule, Paul Chuchana, Laurence Lasorsa, Nathalie Cervera, Mélanie Nugoli, Béatrice Orsetti

Chromosome 17 is severely rearranged in breast cancer. Whereas the short arm undergoes frequent losses, the long arm harbors complex combinations of gains and losses. In this work we present a comprehensive study of quantitative anomalies at chromoso

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58a1759aface2e0bccc9928284d32834
https://doi.org/10.1158/0008-5472.c.6493662.v1

Amplification of the BRCA2 pathway gene EMSY in sporadic breast cancer is related to negative outcome

Autor: Charles Theillet, Hélène Vallès, Lisa Ursule, Luke Hughes-Davies, Marguerite Cuny, Béatrice Orsetti, Tony Kouzarides, Carmen Rodríguez

Publikováno v: Clinical cancer research : an official journal of the American Association for Cancer Research. 10(17)

DNA amplification at band q13 of chromosome 11 is common in breast cancer, and CCND1 and EMS1 remain the strongest candidate genes. However, amplification patterns are consistent with the existence of four cores of amplification, suggesting the invol

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cee76bfb9aa717c6f4239e2cc1286e15
https://pubmed.ncbi.nlm.nih.gov/15355907

Genetic variability in MCF-7 sublines: evidence of rapid genomic and RNA expression profile modifications

Autor: Catherine Nguyen, Charles Theillet, Lisa Ursule, Julie A. Vendrell, Pascale A. Cohen, Paul Chuchana, Béatrice Orsetti, Daniel Birnbaum, Emmanuel J. P. Douzery, Mélanie Nugoli

Publikováno v: BMC Cancer, Vol 3, Iss 1, p 13 (2003)
BMC Cancer
BMC Cancer, 2003, 3, pp.13. ⟨10.1186/1471-2407-3-13⟩
BMC Cancer, BioMed Central, 2003, 3, pp.13. 〈10.1186/1471-2407-3-13〉
BMC Cancer, BioMed Central, 2003, 3, pp.13. ⟨10.1186/1471-2407-3-13⟩

Background Both phenotypic and cytogenetic variability have been reported for clones of breast carcinoma cell lines but have not been comprehensively studied. Despite this, cell lines such as MCF-7 cells are extensively used as model systems. Methods

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f31c5e48689e4a37051b7733880c460e
http://www.biomedcentral.com/1471-2407/3/13

Genetic variability in MCF-7 sublines: evidence of rapid genomic and RNA expression profile modifications.

Autor: Nugoli, Mélanie¹ nugoli@valdorel.fnclcc.fr, Chuchana, Paul¹ chuchana@valdorel.fnclcc.fr, Vendrell, Julie¹ vendrell@valdorel.fnclcc.fr, Orsetti, Béatrice¹ orsetti@valdorel.fnclcc.fr, Ursule, Lisa¹ ursule@valdorel.fnclcc.fr, Nguyen, Catherine² nguyen@ciml.univ-mrs.fr, Birnbaum, Daniel³ birnbaum@marseille.inserm.fr, Douzery, Emmanuel J. P.⁴ douzery@isem.isem.univ-montp2.fr, Cohen, Pascale^1,5 pascale.cohen@ibph.pharma.univ-montp1.fr, Theillet, Charles¹ theillet@valdorel.fnclcc.fr

Publikováno v: BMC Cancer. 2003, Vol. 3, p13-12. 12p. 4 Diagrams, 2 Charts.