Zobrazeno 1 - 10
of 104
pro vyhledávání: '"Lisa Tucker Kellogg"'
Autor:
Ekta Makhija, Yang Zheng, Jiahao Wang, Han Ren Leong, Rashidah Binte Othman, Ee Xien Ng, Eng Hin Lee, Lisa Tucker Kellogg, Yie Hou Lee, Hanry Yu, Zhiyong Poon, Krystyn J Van Vliet
Publikováno v:
PLoS ONE, Vol 19, Iss 3, p e0297769 (2024)
Mesenchymal stromal cells (MSCs) are promising therapeutic agents for cartilage regeneration, including the potential of cells to promote chondrogenesis in vivo. However, process development and regulatory approval of MSCs as cell therapy products be
Externí odkaz:
https://doaj.org/article/fdd2b05d427b4cd58e59d81e91169f02
A computational model of mutual antagonism in the mechano-signaling network of RhoA and nitric oxide
Publikováno v:
BMC Molecular and Cell Biology, Vol 22, Iss S1, Pp 1-12 (2021)
Abstract Background RhoA is a master regulator of cytoskeletal contractility, while nitric oxide (NO) is a master regulator of relaxation, e.g., vasodilation. There are multiple forms of cross-talk between the RhoA/ROCK pathway and the eNOS/NO/cGMP p
Externí odkaz:
https://doaj.org/article/423a93f72dad46b0a531b611110bc7ca
Autor:
Shan Zhang, Boris Reljić, Chao Liang, Baptiste Kerouanton, Joel Celio Francisco, Jih Hou Peh, Camille Mary, Narendra Suhas Jagannathan, Volodimir Olexiouk, Claire Tang, Gio Fidelito, Srikanth Nama, Ruey-Kuang Cheng, Caroline Lei Wee, Loo Chien Wang, Paula Duek Roggli, Prabha Sampath, Lydie Lane, Enrico Petretto, Radoslaw M. Sobota, Suresh Jesuthasan, Lisa Tucker-Kellogg, Bruno Reversade, Gerben Menschaert, Lei Sun, David A. Stroud, Lena Ho
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Small open reading frame-encoded peptides (SEPs), shorter than 100 amino acids, are involved in many cell biological processes. Here the authors identify 16 nuclear-encoded mitochondrial SEPs, including BRAWNIN, an essential regulator of respiratory
Externí odkaz:
https://doaj.org/article/0910631e426f49c8a20e80729e44b71d
Autor:
Angeline Rouers, Melissa Hui Yen Chng, Bernett Lee, Menaka P. Rajapakse, Kaval Kaur, Ying Xiu Toh, Durgalakshmi Sathiakumar, Thomas Loy, Tun-Linn Thein, Vanessa W.X. Lim, Amit Singhal, Tsin Wen Yeo, Yee-Sin Leo, Kalpit A. Vora, Danilo Casimiro, Bing Lim, Lisa Tucker-Kellogg, Laura Rivino, Evan W. Newell, Katja Fink
Publikováno v:
Cell Reports Medicine, Vol 2, Iss 5, Pp 100278- (2021)
Summary: Prior immunological exposure to dengue virus can be both protective and disease-enhancing during subsequent infections with different dengue virus serotypes. We provide here a systematic, longitudinal analysis of B cell, T cell, and antibody
Externí odkaz:
https://doaj.org/article/f584c5014186468ab29c7e9b13295ce9
Autor:
Chenhao Li, Kern Rei Chng, Junmei Samantha Kwah, Tamar V. Av-Shalom, Lisa Tucker-Kellogg, Niranjan Nagarajan
Publikováno v:
Microbiome, Vol 7, Iss 1, Pp 1-14 (2019)
Abstract Background The dynamics of microbial communities is driven by a range of interactions from symbiosis to predator-prey relationships, the majority of which are poorly understood. With the increasing availability of high-throughput microbiome
Externí odkaz:
https://doaj.org/article/16a263a29c304072960bc03e81730be4
Publikováno v:
PLoS Computational Biology, Vol 17, Iss 1, p e1008474 (2021)
Intrinsically disordered regions (IDRs) are prevalent in the eukaryotic proteome. Common functional roles of IDRs include forming flexible linkers or undergoing allosteric folding-upon-binding. Recent studies have suggested an additional functional r
Externí odkaz:
https://doaj.org/article/58ec71c2c94f4c5ea3db58ed9dc0c0b8
Autor:
Jayshree L. Hirpara, Kothandharaman Subramaniam, Gregory Bellot, Jianhua Qu, Serena Seah, Thomas Loh, Lisa Tucker-Kellogg, Marie-Veronique Clement, Shazib Pervaiz
Publikováno v:
Redox Biology, Vol 30, Iss , Pp - (2020)
The death inhibitory proteins, cFLIP and Bcl-2, canonically act at different steps to regulate receptor-mediated apoptosis in cancer cells. Here we report that pharmacological or genetic means to effect an increase in intracellular superoxide result
Externí odkaz:
https://doaj.org/article/feaabb0613ff4be297678c71ee3ef13c
Autor:
N. Suhas Jagannathan, Javier Yu Peng Koh, Younghwan Lee, Radoslaw M Sobota, Aaron Irving, Lin-Fa Wang, Yoko Itahana, Koji Itahana, Lisa Tucker-Kellogg
Bats have unique characteristics compared to other mammals, including increased longevity and higher resistance to cancer and infectious disease. While previous studies have analyzed the metabolic requirements for flight, it is still unclear how bat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::521fff94c4817bd7dfcaddb81b40814e
https://doi.org/10.1101/2023.05.08.537600
https://doi.org/10.1101/2023.05.08.537600
Autor:
Wei-Xiang Sin, Narendra Suhas Jagannathan, Denise Bei Lin Teo, Faris Kairi, Dedy Sandikin, Ka-Wai Cheung, Yie Hou Lee, Rajeev J. Ram, Lisa Tucker-Kellogg, Michael E. Birnbaum
While adoptive cell therapies have revolutionized cancer immunotherapy, current autologous chimeric antigen receptor (CAR) T cell manufacturing face challenges in scaling to meet patient demands. CAR T cell production still largely rely on fed-batch,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9c8c8e17fb217e8255aeaf0ba2cd4899
https://doi.org/10.1101/2023.04.07.535939
https://doi.org/10.1101/2023.04.07.535939
SI Table S1. Treatment parameters for the antagonistic, additive, and synergistic combinations displayed in Fig. 6. SI Fig S1. The trends of TRR and Tlethal according to the Constant-Dose and the Constant-Efficacy Methods, if drug effect is exclusive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73e341b9b1639ef72609c054aa3e65a4
https://doi.org/10.1158/0008-5472.22417716.v1
https://doi.org/10.1158/0008-5472.22417716.v1