Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Lisa Thelen"'
Autor:
Jorge Boucas, Christian Fritz, Anna Schmitt, Arina Riabinska, Lisa Thelen, Martin Peifer, Uschi Leeser, Peter Nuernberg, Janine Altmueller, Matthias Gaestel, Christoph Dieterich, H Christian Reinhardt
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0125745 (2015)
Growing evidence suggests a key role for RNA binding proteins (RBPs) in genome stability programs. Additionally, recent developments in RNA sequencing technologies, as well as mass-spectrometry techniques, have greatly expanded our knowledge on prote
Externí odkaz:
https://doaj.org/article/74cdcbf741ad491c99915e8c7231fc0e
Autor:
H. Christian Reinhardt, Lukas C. Heukamp, Winfried Edelmann, Johanna van Oers, Uschi Leeser, Gero Knittel, Laura Ivan, Ron D. Jachimowicz, Mladen Jokic, Lisa Thelen, Felix Dietlein
PDF file 129K, Supplementary Methods provide additional information on experimental techniques and data analysis. Supplementary Legends describe supplementary figures S1-S10 and supplementary table S1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75160b20592e9f67b8aba646ceb3a10a
https://doi.org/10.1158/2159-8290.22529808
https://doi.org/10.1158/2159-8290.22529808
Autor:
H. Christian Reinhardt, Lukas C. Heukamp, Winfried Edelmann, Johanna van Oers, Uschi Leeser, Gero Knittel, Laura Ivan, Ron D. Jachimowicz, Mladen Jokic, Lisa Thelen, Felix Dietlein
PDF file 3500K, Potency of KU60648 across 94 cancer cell lines (Figure S1), comparison of KU60648-sensitivity in mutant vs. wildtype lines for 9 exemplary DNA repair-associated genes (Figure S2), MSH3 variants and Sanger sequencing of BRCA1 (Figure S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3db39079aecdda6f5c42924ff6abace2
https://doi.org/10.1158/2159-8290.22529814.v1
https://doi.org/10.1158/2159-8290.22529814.v1
Autor:
H. Christian Reinhardt, Lukas C. Heukamp, Winfried Edelmann, Johanna van Oers, Uschi Leeser, Gero Knittel, Laura Ivan, Ron D. Jachimowicz, Mladen Jokic, Lisa Thelen, Felix Dietlein
PDF file 37K, List of all cell lines included in this study. Cell line name, GI50 of KU60648 from initial cell line screen, sensitivity classification as well as mutation annotation source are recorded
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0a8406a03aac1a7c1207c55c27a0013
https://doi.org/10.1158/2159-8290.22529811.v1
https://doi.org/10.1158/2159-8290.22529811.v1
Autor:
Phuong-Hien Nguyen, Nina Reinart, Maximilian Koch, Oleg Fedorchenko, Michael Hallek, Sebastian Reinartz, Tamina Seeger-Nukpezah, Natascha Rosen, Gero Knittel, Julia Saggau, Romy Barthel, Lisa Thelen, Hans Christian Reinhardt
Publikováno v:
Cancers
Cancers, Vol 12, Iss 1980, p 1980 (2020)
Cancers, Vol 12, Iss 1980, p 1980 (2020)
The Eµ-TCL1 transgenic mouse model represents the most widely and extensively used animal model for chronic lymphocytic leukemia (CLL). In this report, we performed a meta-analysis of leukemia progression in over 300 individual Eµ-TCL1 transgenic m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d519be079352abf0071348d70534710
http://europepmc.org/articles/PMC7409315
http://europepmc.org/articles/PMC7409315
Publikováno v:
Pharmacology Research & Perspectives
Enhanced expression of the proteinase‐activated receptor 2 (PAR2) is linked to cell proliferation and migration in many cancer cell types. The role of PAR2 in cancer progression strongly illustrates the need for PAR2‐inhibiting compounds. However
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e583f5f85300af79202be8e3ba1e462a
https://pubmed.ncbi.nlm.nih.gov/28116092
https://pubmed.ncbi.nlm.nih.gov/28116092
Autor:
Lisa Thelen, Jorge Boucas, H. Christian Reinhardt, U. Leeser, Arina Riabinska, Janine Altmueller, Christoph Dieterich, Christian Fritz, Martin Peifer, Anna Schmitt, Peter Nuernberg, Matthias Gaestel
Publikováno v:
PLoS ONE
PLoS One
PLoS ONE, Vol 10, Iss 5, p e0125745 (2015)
PLoS One
PLoS ONE, Vol 10, Iss 5, p e0125745 (2015)
Growing evidence suggests a key role for RNA binding proteins (RBPs) in genome stability programs. Additionally, recent developments in RNA sequencing technologies, as well as mass-spectrometry techniques, have greatly expanded our knowledge on prote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f4db440154c441145ca383a591d818f
http://europepmc.org/articles/PMC4439058
http://europepmc.org/articles/PMC4439058
Autor:
Gero Knittel, Ron D. Jachimowicz, Lisa Thelen, Lukas C. Heukamp, U. Leeser, Winfried Edelmann, Johanna van Oers, Felix Dietlein, Mladen Jokic, Laura Ivan, H. Christian Reinhardt
Publikováno v:
Europe PubMed Central
Cancer Discov
Cancer Discov
Here, we use a large-scale cell line–based approach to identify cancer cell–specific mutations that are associated with DNA-dependent protein kinase catalytic subunit (DNA-PKcs) dependence. For this purpose, we profiled the mutational landscape a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::faa02a635e44c5578f7c03728b31090c
https://pubmed.ncbi.nlm.nih.gov/24556366
https://pubmed.ncbi.nlm.nih.gov/24556366
Autor:
Lisa Thelen
Facharbeit (Schule) aus dem Jahr 2012 im Fachbereich Geschichte - Sonstiges, Note: 1,25,, Sprache: Deutsch, Abstract: Was hat mich dazu bewegt über die Edelweißpiraten eine Facharbeit zu schreiben? Nun ja, das ist eine gute Frage, die sich aber den