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pro vyhledávání: '"Lisa Swanton"'
Autor:
Jingshu Liu, Forbes D C Manson, Travis Knudsen, Rachel L. Taylor, Richard A. Baines, Barbara Corneo, Graeme C.M. Black, Lisa Swanton, Sally Freeman, Alan D. Marmorstein, Achchhe Patel
Publikováno v:
Liu, J, Taylor, R L, Baines, R, Swanton, E, Freeman, S, Corneo, B, Patel, A, Marmorstein, A, Knudson, T, Black, G & Manson, F 2020, ' Small Molecules Restore Bestrophin 1 Expression and Function of Both Dominant and Recessive Bestrophinopathies in Patient-Derived Retinal Pigment Epithelium. ', Investigative ophthalmology & visual science, vol. 61, no. 5, 28 . https://doi.org/10.1167/iovs.61.5.28
Investigative Ophthalmology & Visual Science
Investigative Ophthalmology & Visual Science
Purpose: Bestrophinopathies are a group of untreatable inherited retinal dystrophies caused by mutations in the retinal pigment epithelium (RPE) Cl− channel bestrophin 1. We tested whether sodium phenylbutyrate (4PBA) could rescue the function of m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26b950c5aa451854fa595a51cdc09147
https://www.research.manchester.ac.uk/portal/en/publications/small-molecules-restore-bestrophin-1-expression-and-function-of-both-dominant-and-recessive-bestrophinopathies-in-patientderived-retinal-pigment-epithelium(5a73418e-ddcd-42c0-977d-aa37baa91aff).html
https://www.research.manchester.ac.uk/portal/en/publications/small-molecules-restore-bestrophin-1-expression-and-function-of-both-dominant-and-recessive-bestrophinopathies-in-patientderived-retinal-pigment-epithelium(5a73418e-ddcd-42c0-977d-aa37baa91aff).html
Autor:
Magdalena Mazurkiewicz, Ellin-Kristina Hillert, Mårten Fryknäs, Lisa Swanton, Stig Linder, Slavica Brjnic, Stephen High, Rolf Larsson, Padraig D'Arcy
Publikováno v:
Cancer Research. 78:1859-1859
Proteasome inhibitors kill cancer cells by inducing an acute proteotoxic stress response characterized by the cytosolic accumulation of poly-ubiquitinated proteins, ER stress and the production of reactive oxygen species (ROS). The aggresome pathway
Publikováno v:
Molecular Membrane Biology. 25:332-343
The last decade has witnessed an exponential increase in interest in one of the great mysteries of nerve cell biology: Specifically, how do neurons know where to place the ion channels that control their excitability? Many of the most important insig