Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Lisa Selzner"'
Autor:
Sibylle Frase, Sandra Kaiser, Matti Steimer, Lisa Selzner, Niels Alexander Foit, Wolf-Dirk Niesen, Nils Schallner
Publikováno v:
Life, Vol 11, Iss 2, p 124 (2021)
Circadian rhythm gene expression in cerebral pacemaker regions is regulated by a transcriptional-translational feedback loop across the 24-h day-night cycle. In preclinical models of subarachnoid hemorrhage (SAH), cyclic gene expression is disrupted.
Externí odkaz:
https://doaj.org/article/ffcaecf438c74b93bd3030af6e19e3d1
Autor:
Sandra Kaiser, Sibylle Frase, Lisa Selzner, Judith-Lisa Lieberum, Jakob Wollborn, Wolf-Dirk Niesen, Niels Alexander Foit, Dieter Henrik Heiland, Nils Schallner
Publikováno v:
Antioxidants, Vol 8, Iss 10, p 496 (2019)
(1) Background: A detailed understanding of the pathophysiology of hemorrhagic stroke is still missing. We hypothesized that expression of heme oxygenase-1 (HO-1) in microglia functions as a protective signaling pathway. (2) Methods: Hippocampal HT22
Externí odkaz:
https://doaj.org/article/885d6382677e43dfaa51aff5b9cf20e6
Autor:
Nils Schallner, Matti Steimer, Sibylle Frase, Sandra Kaiser, Wolf-Dirk Niesen, Niels Alexander Foit, Lisa Selzner
Publikováno v:
Neurocritical Care. 36:279-291
Background Red blood cell-induced cerebral inflammation and toxicity has been shown to be attenuated by induction of the heme-catalyzing enzyme, hemoxygenase-1 (HO-1), in animal models of subarachnoid hemorrhage (SAH). Although inflammatory mechanism
Publikováno v:
Glia.
Microglial erythrophagocytosis is crucial in injury response to hemorrhagic stroke. We hypothesized that regulation of microglial erythrophagocytosis via HO-1/CO depends on a pathway involving reactive oxygen species (ROS) and CD36 surface-expression