Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Lisa S. Uyechi"'
Publikováno v:
Gene Therapy for Diseases of the Lung ISBN: 9781003064619
The delivery of nucleic acids for therapeutic purposes must surmount multiple cellular barriers that restrict efficient gene delivery. Manipulation of the biology of the cell and association of various effectors with the nucleic acid or utilization o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::326b31ac692881a96a0b2861b58dfaf9
https://doi.org/10.1201/9781003064619-11
https://doi.org/10.1201/9781003064619-11
Autor:
Frederick Cohen, Michael R. Scott, Lisa S. Uyechi, Jiri G. Safar, Francis C. Szoka, Holger Wille, Patrick Tremblay, Stanley B. Prusiner, Surachai Supattapone
Publikováno v:
Journal of Virology. 75:3453-3461
Branched polyamines, including polyamidoamine and polypropyleneimine (PPI) dendrimers, are able to purge PrP Sc , the disease-causing isoform of the prion protein, from scrapie-infected neuroblastoma (ScN2a) cells in culture (S. Supattapone, H.-O. B.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54210ba02847ff9043f1fcbba42a81bf
https://doi.org/10.1128/jvi.75.7.3453-3461.2001
https://doi.org/10.1128/jvi.75.7.3453-3461.2001
Publikováno v:
Gene therapy. 8(11)
We introduce a lung inflation-fixation protocol to examine the distribution and gene transfer efficiency of fluorescently tagged lipoplexes using fluorescence confocal microscopy within thick lung tissue sections. Using this technique, we tested the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af138805875697b9e3c44b0b8245820e
https://pubmed.ncbi.nlm.nih.gov/11423930
https://pubmed.ncbi.nlm.nih.gov/11423930
Publikováno v:
Biochimica et biophysica acta. 1390(2)
The interactions among serum components and cationic lipid–nucleic acid complexes are central to the understanding of how serum inhibits cellular delivery of oligonucleotides in vitro and in vivo. In this study, we show that several serum proteins,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a54471ad30304d46615414fb533548ca
https://pubmed.ncbi.nlm.nih.gov/9507083
https://pubmed.ncbi.nlm.nih.gov/9507083