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pro vyhledávání: '"Lisa S. Silverman"'
Autor:
Lisa S. Silverman, Hillary N. Fouts
Publikováno v:
Human nature (Hawthorne, N.Y.). 26(1)
The majority of adaptationist models and research related to parenting strategies have focused on extrinsic or population-level risk as predictors of parenting. However, some researchers have called for greater consideration of cultural factors as we
Autor:
Peter Korakas, Duane A. Burnett, Rosalia Bertorelli, Gianluca Lozza, Stephanie Brumfield, T.K. Sasikumar, Cheng Li, Angelo Reggiani, Chad Bennett, Martin S. Domalski, Lisa S. Silverman, Wen-Lian Wu, Li Qiang, Julius Matasi, Chad E. Knutson, Deen Tulshian, Mariagrazia Grilli, William J. Greenlee
Publikováno v:
Bioorganicmedicinal chemistry letters. 22(23)
High throughput screening identified the pyridothienopyrimidinone 1 as a ligand for the metabotropic glutamate receptor 1 (mGluR1=10 nM). Compound 1 has an excellent in vivo profile; however, it displays unfavorable pharmacokinetic issues and metabol
Publikováno v:
Journal of natural products. 56(8)
Clavaminate synthase is an FeII/alpha-ketoglutarate-dependent enzyme central to the biosynthesis of the beta-lactamase inhibitor clavulanic acid. In the presence of dioxygen it catalyzes the oxidative cyclization/desaturation of proclavaminic acid to