Zobrazeno 1 - 10
of 112
pro vyhledávání: '"Lisa S. Poritz"'
Autor:
Wei Yu, John P Hegarty, Arthur Berg, Xi Chen, Gail West, Ashley A Kelly, Yunhua Wang, Lisa S Poritz, Walter A Koltun, Zhenwu Lin
Publikováno v:
PLoS ONE, Vol 6, Iss 5, p e20454 (2011)
BACKGROUND: NKX2-3 is associated with inflammatory bowel disease (IBD). NKX2-3 is expressed in microvascular endothelial cells and the muscularis mucosa of the gastrointestinal tract. Human intestinal microvascular endothelial cells (HIMECs) are acti
Externí odkaz:
https://doaj.org/article/585a119ec804442c9b15dafef409e73b
Autor:
Andrés Hurtado-Lorenzo, Alessandro Fichera, Constanza J. Cortes, Lisa S. Poritz, Thaddeus S. Stappenbeck, Scott B. Snapper, Jeremiah J. Faith, Richard A. Hodin, Florian Rieder, Nataly Shtraizent, Sarkis K. Mazmanian, Theresa T. Pizarro, Jean-Frederic Colombel, Jennifer E. Towne, Michael J. Rosen, Mark Donowitz, Eugene B. Chang, Nita H. Salzman, Gerard Honig, Wendy S. Garrett
Publikováno v:
Inflammatory bowel diseases. 25(Suppl 2)
Preclinical human IBD mechanisms is part of five focus areas of the Challenges in IBD research document, which also include environmental triggers, novel technologies, precision medicine and pragmatic clinical research. The Challenges in IBD research
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f7432eae57a84cd688d0a68e279d2db
https://pubmed.ncbi.nlm.nih.gov/31095706
https://pubmed.ncbi.nlm.nih.gov/31095706
Development of a total colectomy and ileorectal anastomosis rat model to evaluate colonic metaplasia
Background Ulcerative colitis is an idiopathic inflammatory condition of the colon that may require surgical intervention including proctocolectomy and either ileal pouch-anal anastomosis or in the pediatric population, low ileorectal anastomosis (IR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bfeb0acc765279958769655b80febfe
https://europepmc.org/articles/PMC5657454/
https://europepmc.org/articles/PMC5657454/
Autor:
Lisa S. Poritz
Publikováno v:
Difficult Decisions in Colorectal Surgery ISBN: 9783319402222
Approximately 30 % of patients with Crohn’s disease (CD) will have or develop perianal fistulas (PF) during the course of their disease. Not only do symptomatic PF cause pain and drainage, they may also lead to sepsis, incontinence, restriction of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7f0cd3ebf5b23f646e9f3bada33ee9c0
https://doi.org/10.1007/978-3-319-40223-9_3
https://doi.org/10.1007/978-3-319-40223-9_3
The TNFSF15 Gene Single Nucleotide Polymorphism rs7848647 Is Associated With Surgical Diverticulitis
Autor:
Arthur Berg, David L. Brinton, John P. Hegarty, Tara M. Connelly, Walter A. Koltun, Sue Deiling, Lisa S. Poritz
Publikováno v:
Annals of Surgery. 259:1132-1137
To determine if single nuclear polymorphisms (SNPs) in the TFNSF15 gene play a role in patients requiring surgery for diverticulitis.A role for a genetic predisposition in diverticulitis is suggested by its association with hereditary connective tiss
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::193b9246f9b6e4ffe5b20898c1bc807f
https://doi.org/10.1097/sla.0000000000000232
https://doi.org/10.1097/sla.0000000000000232
Autor:
Walter A. Koltun, Javier S. Pogacnik, Lisa S. Poritz, Tara M. Connelly, Evangelos Messaris, Kevin J. McKenna, Arthur Berg, Susan Deiling, David B. Stewart
Publikováno v:
Journal of the American College of Surgeons. 218:920-928
Background We aimed to determine if an increased incidence of incisional hernias is present in patients undergoing sigmoidectomy for diverticulitis vs cancer. The pathophysiology of diverticulitis is poorly understood, but might involve a collagen va
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::55a1ee7ab509309a4a1777a7fbe39c5e
https://doi.org/10.1016/j.jamcollsurg.2014.01.050
https://doi.org/10.1016/j.jamcollsurg.2014.01.050
Autor:
Christine S. Choi, Rishabh Sehgal, Arthur Berg, Lisa S. Poritz, Emmanuelle Williams, Lacee J. Laufenberg
Publikováno v:
Journal of Gastrointestinal Surgery. 17:1027-1031
Bacteria have been implicated in the development of pouchitis after ileal pouch anal anastomosis. The change in gastric pH with the use of proton pump inhibitors and H(2) antagonists may lead to alteration of enteric bacteria. We hypothesized that ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e283ea155d2d01c5d0fc63941adaec34
https://doi.org/10.1007/s11605-013-2172-y
https://doi.org/10.1007/s11605-013-2172-y
Publikováno v:
Journal of Gastrointestinal Surgery. 16:2267-2273
Recurrent Clostridium difficile colitis (RCDC) is common, but data regarding recurrence rates and predisposing factors are sparse. A retrospective case–control study was performed, identifying all inpatients and outpatients ≥18 years of age with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75330cdd9629d320883c1a1e6dfaf539
https://doi.org/10.1007/s11605-012-2037-9
https://doi.org/10.1007/s11605-012-2037-9
Autor:
Pieter W. Faber, Yunhua Wang, Walter A. Koltun, Xi Chen, Jian-Bing Fan, Zhenwu Lin, John P. Hegarty, Jon A. Cappel, Wei Yu, Lisa S. Poritz
Publikováno v:
Digestive Diseases and Sciences. 57:3145-3153
Changes in the methylation status of inflammatory bowel disease (IBD)-associated genes could significantly alter levels of gene expression, thereby contributing to disease onset and progression. We previously identified seven disease-associated DNA m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1822f267437c501dcf776bbf07fb412
https://doi.org/10.1007/s10620-012-2288-z
https://doi.org/10.1007/s10620-012-2288-z
Autor:
Wei Yu, John P. Hegarty, Arthur Berg, Ashley A. Kelly, Yunhua Wang, Lisa S. Poritz, Andre Franke, Stefan Schreiber, Walter A. Koltun, Zhenwu Lin
Publikováno v:
Disease markers
Disease Markers, Vol 32, Iss 2, Pp 83-91 (2012)
Disease Markers, Vol 32, Iss 2, Pp 83-91 (2012)
PTPN2 is a risk gene for Crohn's disease (CD). We investigated whether PTPN2 genetic variants (rs2542151 and rs2542152) were associated with CD in a familial IBD registry. Both rs2542151 and rs2542152 are associated with CD, but not ulcerative coliti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bd9b1b1e16190c41e8b44a838f716b2
http://europepmc.org/articles/PMC3826479
http://europepmc.org/articles/PMC3826479