Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Lisa S. Hancox"'
Autor:
Mitchell N. Lefebvre, Fionna A. Surette, Scott M. Anthony, Rahul Vijay, Isaac J. Jensen, Lecia L. Pewe, Lisa S. Hancox, Natalija Van Braeckel-Budimir, Stephanie van de Wall, Stina L. Urban, Madison R. Mix, Samarchith P. Kurup, Vladimir P. Badovinac, Noah S. Butler, John T. Harty
Publikováno v:
Cell Reports, Vol 37, Iss 5, Pp 109956- (2021)
Summary: Circulating memory CD8 T cell trafficking and protective capacity during liver-stage malaria infection remains undefined. We find that effector memory CD8 T cells (Tem) infiltrate the liver within 6 hours after malarial or bacterial infectio
Externí odkaz:
https://doaj.org/article/bd5f91fa19ff4eed920a3ac786cb0f9f
Publikováno v:
The Journal of Immunology. 210:1305-1313
Production of IFN-γ by CD4 T cells is widely theorized to control Plasmodium parasite burden during blood-stage malaria. Surprisingly, the specific and crucial mechanisms through which this highly pleiotropic cytokine acts to confer protection again
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b1d1e60db1b059d22886913fea31d3da
https://doi.org/10.4049/jimmunol.2200899
https://doi.org/10.4049/jimmunol.2200899
Autor:
Camila Marques-da-Silva, Barun Poudel, Rodrigo P. Baptista, Kristen Peissig, Lisa S. Hancox, Justine C. Shiau, Lecia L. Pewe, Melanie J. Shears, Thirumala-Devi Kanneganti, Photini Sinnis, Dennis E. Kyle, Prajwal Gurung, John T. Harty, Samarchith P. Kurup
Publikováno v:
Proceedings of the National Academy of Sciences. 120
Malaria, caused by Plasmodium parasites is a severe disease affecting millions of people around the world. Plasmodium undergoes obligatory development and replication in the hepatocytes, before initiating the life-threatening blood-stage of malaria.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::79df7f6e3dbaccedf0a4ffed1762ed50
https://doi.org/10.1073/pnas.2210181120
https://doi.org/10.1073/pnas.2210181120
Autor:
Lisa L Drewry, John T. Harty, Mitchell N. Lefebvre, Arturo Reyes-Sandoval, Lisa S. Hancox, Lecia L. Pewe
Publikováno v:
J Immunol
Radiation-attenuated sporozoite (RAS) vaccination offers hope for global malaria control through induction of protective liver-stage–specific memory CD8 T cells. Effective RAS vaccination regimens exist; however, widespread implementation remains u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c6eb784c004ff43f09d63e108505092
https://pubmed.ncbi.nlm.nih.gov/34716185
https://pubmed.ncbi.nlm.nih.gov/34716185
Autor:
Isaac J. Jensen, Fionna A. Surette, Lisa S. Hancox, Noah S. Butler, Scott M. Anthony, Madison R Mix, Vladimir P. Badovinac, Samarchith P. Kurup, John T. Harty, Mitchell N. Lefebvre, Stina L. Urban, Rahul Vijay, Stephanie van de Wall, Lecia L. Pewe, Natalija Van Braeckel-Budimir
Publikováno v:
Cell Reports, Vol 37, Iss 5, Pp 109956-(2021)
Summary Circulating memory CD8 T cell trafficking and protective capacity during liver-stage malaria infection remains undefined. We find that effector memory CD8 T cells (Tem) infiltrate the liver within 6 hours after malarial or bacterial infection
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ff4ee86b32516f1ffae8b4d25b9e19b
https://pubmed.ncbi.nlm.nih.gov/34836817
https://pubmed.ncbi.nlm.nih.gov/34836817
Autor:
Prajwal Gurung, Samarchith P. Kurup, John T. Harty, Photini Sinnis, Rodrigo P. Baptista, Lecia L. Pewe, Camila Marques-da-Silva, Barun Poudel, Lisa S. Hancox, Justine C. Shiau, Melanie J. Shears, Thirumala-Devi Kanneganti, Kristen Peissig, Dennis E. Kyle
Malaria, caused by Plasmodium parasites, is a devastating disease that kills over half a million people each year1. Plasmodium sporozoites inoculated by mosquitoes into mammalian hosts undergo a clinically silent phase of obligatory development and r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::448b05503463b25fe08ed983e095ed15
https://doi.org/10.1101/2021.01.28.427517
https://doi.org/10.1101/2021.01.28.427517
Autor:
Lisa S. Hancox, Lecia L. Pewe, Samarchith P. Kurup, John T. Harty, Shahid M. Khan, Chris J. Janse, Scott M. Anthony, Ramakrishna Sompallae, Rahul Vijay, Steven J Moioffer
Publikováno v:
Cell Host and Microbe, 25(4), 565-+. CELL PRESS
Summary Plasmodium sporozoites inoculated by mosquitoes migrate to the liver and infect hepatocytes prior to release of merozoites that initiate symptomatic blood-stage malaria. Plasmodium parasites are thought to be restricted to hepatocytes through
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b25c0960aa4c2469e01a0ffe2c5113b0
https://hdl.handle.net/1887/122209
https://hdl.handle.net/1887/122209
Autor:
Bert Gold, Karen M. Gehrs, Gregory S. Hageman, Joanna E. Merriam, David J. Kavanagh, John P. Atkinson, Julie Bergeron, Lincoln V. Johnson, Lisa S. Hancox, Seppo Meri, Michael Dean, Andrew J Taiber, Monte J. Radeke, Don H. Anderson, Rando Allikmets, Jana Zernant, Anna Richards
Publikováno v:
Annals of medicine. 38(8)
Variants in the complement factor H gene (CFH) are associated with age-related macular degeneration (AMD). CFH and five CFH-related genes (CFHR1-5) lie within the regulators of complement activation (RCA) locus on chromosome 1q32. Aims and Methods. I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2998d0fdee0f06d80132a54a060feea
https://pubmed.ncbi.nlm.nih.gov/28950782
https://pubmed.ncbi.nlm.nih.gov/28950782
Autor:
Lisa S. Hancox, Steven M. Varga, Martin J. Richer, Stacey M. Hartwig, John T. Harty, Lecia L. Pewe
Publikováno v:
The Journal of clinical investigation. 125(9)
Due to their ability to rapidly proliferate and produce effector cytokines, memory CD8+ T cells increase protection following reexposure to a pathogen. However, low inflammatory immunizations do not provide memory CD8+ T cells with a proliferation ad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1c95d44fdfe96452ad63271f9cd0bab
https://pubmed.ncbi.nlm.nih.gov/26241055
https://pubmed.ncbi.nlm.nih.gov/26241055
Autor:
Aissata Ongoiba, Lisa S. Hancox, Jill D. Coursen, Boubacar Traore, Chiung Yu Huang, Peter D. Crompton, Silvia Portugal, John T. Harty, Tuan M. Tran, Simran Banga, Ogobara K. Doumbo
Publikováno v:
PLoS ONE
PLoS ONE, Vol 10, Iss 4, p e0125090 (2015)
PLoS One
PLoS ONE, Vol 10, Iss 4, p e0125090 (2015)
PLoS One
Vaccine-induced immunity depends on long-lived plasma cells (LLPCs) that maintain antibody levels. A recent mouse study showed that Plasmodium chaubaudi infection reduced pre-existing influenza-specific antibodies--raising concerns that malaria may c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01c267ad75633ff2b6eed4f6aae9477f
https://pubmed.ncbi.nlm.nih.gov/25919588
https://pubmed.ncbi.nlm.nih.gov/25919588