Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Lisa S Ang"'
Autor:
Erolcan Sayar, Radhika A. Patel, Ilsa M. Coleman, Martine P. Roudier, Ailin Zhang, Pallabi Mustafi, Jin-Yih Low, Brian Hanratty, Lisa S. Ang, Vipul Bhatia, Mohamed Adil, Hasim Bakbak, David A. Quigley, Michael T. Schweizer, Jessica E. Hawley, Lori Kollath, Lawrence D. True, Felix Y. Feng, Neil H. Bander, Eva Corey, John K. Lee, Colm Morrissey, Roman Gulati, Peter S. Nelson, Michael C. Haffner
Publikováno v:
JCI Insight, Vol 8, Iss 7 (2023)
Prostate-specific membrane antigen (PSMA) is an important cell surface target in prostate cancer. There are limited data on the heterogeneity of PSMA tissue expression in metastatic castration-resistant prostate cancer (mCRPC). Furthermore, the mecha
Externí odkaz:
https://doaj.org/article/bf1e39c95aad42bb924c7ccfb3af7d25
Autor:
Navonil De Sarkar, Sayan Dasgupta, Payel Chatterjee, Ilsa Coleman, Gavin Ha, Lisa S. Ang, Emily A. Kohlbrenner, Sander B. Frank, Talina A. Nunez, Stephen J. Salipante, Eva Corey, Colm Morrissey, Eliezer Van Allen, Michael T. Schweizer, Michael C. Haffner, Radhika Patel, Brian Hanratty, Jared M. Lucas, Ruth F. Dumpit, Colin C. Pritchard, Robert B. Montgomery, Peter S. Nelson
Publikováno v:
JCI Insight, Vol 6, Iss 23 (2021)
Cancers with homology-directed DNA repair (HRR) deficiency exhibit high response rates to poly(ADP-ribose) polymerase inhibitors (PARPi) and platinum chemotherapy. Though mutations disrupting BRCA1 and BRCA2 associate with HRR deficiency (HRRd), patt
Externí odkaz:
https://doaj.org/article/e560f44694e145f28e8ec0e2865f09db
Autor:
Gavin Ha, Peter S. Nelson, Steven Henikoff, Eva Corey, R. Bruce Montgomery, Michael C. Haffner, Kami Ahmad, Matthew L. Freedman, Jacob E. Berchuck, Sylvan C. Baca, Atish D. Choudhury, Colm Morrissey, Michael T. Schweizer, Colin C. Pritchard, Heather M. McClure, Holly M. Nguyen, Talina A. Nunez, Jared M. Lucas, Ruth F. Dumpit, Arnab Bose, Ilsa M. Coleman, Lisa S. Ang, Derek H. Janssens, Michael P. Meers, Sandipan Brahma, Minjeong Ko, Jay F. Sarthy, Adam J. Kreitzman, Mohamed Adil, Brian Hanratty, Anna-Lisa Doebley, Robert D. Patton, Navonil De Sarkar
Feature-region combination AUCs and benchmarking Sheet 1: Log2 fold-change, p-value, and q-value between ARPC and NEPC lines for central mean coverage in all queried (338) TFs (two tailed Mann-Whitney U test, Benjamini-Hochberg adjusted). Sheet 2: 10
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::131f41ff743e41934b8e4242f49253ae
https://doi.org/10.1158/2159-8290.22674256
https://doi.org/10.1158/2159-8290.22674256
Autor:
Gavin Ha, Peter S. Nelson, Steven Henikoff, Eva Corey, R. Bruce Montgomery, Michael C. Haffner, Kami Ahmad, Matthew L. Freedman, Jacob E. Berchuck, Sylvan C. Baca, Atish D. Choudhury, Colm Morrissey, Michael T. Schweizer, Colin C. Pritchard, Heather M. McClure, Holly M. Nguyen, Talina A. Nunez, Jared M. Lucas, Ruth F. Dumpit, Arnab Bose, Ilsa M. Coleman, Lisa S. Ang, Derek H. Janssens, Michael P. Meers, Sandipan Brahma, Minjeong Ko, Jay F. Sarthy, Adam J. Kreitzman, Mohamed Adil, Brian Hanratty, Anna-Lisa Doebley, Robert D. Patton, Navonil De Sarkar
Supplementary Figures S1-S18 and Supplementary Table legends.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a676746f9874d80588b96e87e41d0812
https://doi.org/10.1158/2159-8290.22674268.v1
https://doi.org/10.1158/2159-8290.22674268.v1
Autor:
Michael C. Haffner, Colin C. Pritchard, Colm Morrissey, Peter S. Nelson, Angelo M. De Marzo, Lawrence D. True, John K. Lee, Gavin Ha, Maria S. Tretiakova, Jin-Yih Low, Lisa S. Ang, Jared M. Lucas, Ruth Dumpit, Brian Hanratty, Eric Q. Konnick, Martine P. Roudier, Ilsa Coleman, Radhika A. Patel
Anaplastic lymphoma kinase (ALK) is a tyrosine kinase with genomic and expression changes in many solid tumors. ALK inhibition is the first-line therapy for lung cancers with ALK alterations, and an effective therapy in other tumor types, but has not
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25646326e6abdc2a05ef2261ba0945d7
https://doi.org/10.1158/2767-9764.c.6550595.v1
https://doi.org/10.1158/2767-9764.c.6550595.v1
Autor:
Michael C. Haffner, Colin C. Pritchard, Colm Morrissey, Peter S. Nelson, Angelo M. De Marzo, Lawrence D. True, John K. Lee, Gavin Ha, Maria S. Tretiakova, Jin-Yih Low, Lisa S. Ang, Jared M. Lucas, Ruth Dumpit, Brian Hanratty, Eric Q. Konnick, Martine P. Roudier, Ilsa Coleman, Radhika A. Patel
Supplementary Figures 1-19, Tables 1-2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2162f12980b1a0f8d2e9939fc711ed1b
https://doi.org/10.1158/2767-9764.22544270.v1
https://doi.org/10.1158/2767-9764.22544270.v1
Autor:
Radhika A. Patel, Ilsa Coleman, Martine P. Roudier, Eric Q. Konnick, Brian Hanratty, Ruth Dumpit, Jared M. Lucas, Lisa S. Ang, Jin-Yih Low, Maria S. Tretiakova, Gavin Ha, John K. Lee, Lawrence D. True, Angelo M. De Marzo, Peter S. Nelson, Colm Morrissey, Colin C. Pritchard, Michael C. Haffner
Publikováno v:
Cancer Res Commun
Anaplastic lymphoma kinase (ALK) is a tyrosine kinase with genomic and expression changes in many solid tumors. ALK inhibition is the first-line therapy for lung cancers with ALK alterations, and an effective therapy in other tumor types, but has not
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e19f78a17326b5e3f6054b4219055a4c
https://doi.org/10.1158/2767-9764.crc-21-0156
https://doi.org/10.1158/2767-9764.crc-21-0156
Autor:
Mitchell G. Lawrence, Renea A. Taylor, Georgia B. Cuffe, Lisa S. Ang, Ashlee K. Clark, David L. Goode, Laura H. Porter, Clémentine Le Magnen, Nora M. Navone, Jack A. Schalken, Yuzhuo Wang, Wytske M. van Weerden, Eva Corey, John T. Isaacs, Peter S. Nelson, Gail P. Risbridger
Publikováno v:
Nature Reviews. Urology, 20, 371-384
Nature Reviews. Urology, 20, 6, pp. 371-384
Nature Reviews. Urology, 20, 6, pp. 371-384
Item does not contain fulltext Patient-derived xenografts (PDXs) are generated by engrafting human tumours into mice. Serially transplantable PDXs are used to study tumour biology and test therapeutics, linking the laboratory to the clinic. Although
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3dff9e43370e7e5e999cf58ac4271e1d
http://hdl.handle.net/2066/293636
http://hdl.handle.net/2066/293636
Autor:
Navonil De Sarkar, Robert D. Patton, Anna-Lisa Doebley, Brian Hanratty, Mohamed Adil, Adam J. Kreitzman, Jay F. Sarthy, Minjeong Ko, Sandipan Brahma, Michael P. Meers, Derek H. Janssens, Lisa S. Ang, Ilsa M. Coleman, Arnab Bose, Ruth F. Dumpit, Jared M. Lucas, Talina A. Nunez, Holly M. Nguyen, Heather M. McClure, Colin C. Pritchard, Michael T. Schweizer, Colm Morrissey, Atish D. Choudhury, Sylvan C. Baca, Jacob E. Berchuck, Matthew L. Freedman, Kami Ahmad, Michael C. Haffner, R. Bruce Montgomery, Eva Corey, Steven Henikoff, Peter S. Nelson, Gavin Ha
Publikováno v:
Cancer discovery.
Advanced prostate cancers comprise distinct phenotypes, but tumor classification remains clinically challenging. Here, we harnessed circulating tumor DNA (ctDNA) to study tumor phenotypes by ascertaining nucleosome positioning patterns associated wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd833af6a03c1560ba09d49700a21b84
https://pubmed.ncbi.nlm.nih.gov/36399432
https://pubmed.ncbi.nlm.nih.gov/36399432
Autor:
Trevor M. Penning, Elahe A. Mostaghel, Alvin M. Matsumoto, Ailin Zhang, Daniel Tamae, Xiaotun Zhang, Lawrence D. True, Heather E. Biehl, Peter S. Nelson, Maria S. Tretiakova, Susana A. Hernandez, Brett T. Marck, Jon Bartlett, John Burns, Eva Corey, Lisa S Ang, Steven P. Balk, Ruth Dumpit, Colm Morrissey
Publikováno v:
Clinical Cancer Research. 25:426-439
Purpose: Tumor androgens in castration-resistant prostate cancer (CRPC) reflect de novo intratumoral synthesis or adrenal androgens. We used C.B.-17 SCID mice in which we observed adrenal CYP17A activity to isolate the impact of adrenal steroids on C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08ad48c889d927010e6416bb3c6b53b8
https://doi.org/10.1158/1078-0432.ccr-18-1431
https://doi.org/10.1158/1078-0432.ccr-18-1431