Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Lisa Ryner"'
Autor:
Mélanie Desbois, Akshata R. Udyavar, Lisa Ryner, Cleopatra Kozlowski, Yinghui Guan, Milena Dürrbaum, Shan Lu, Jean-Philippe Fortin, Hartmut Koeppen, James Ziai, Ching-Wei Chang, Shilpa Keerthivasan, Marie Plante, Richard Bourgon, Carlos Bais, Priti Hegde, Anneleen Daemen, Shannon Turley, Yulei Wang
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
The exclusion of T cells from solid tumours is a potentially important mechanism that regulates whether or not cancer patients respond well to checkpoint blocking immunotherapies. Here the authors identify immune phenotypes and mediators of T cell ex
Externí odkaz:
https://doaj.org/article/e31d51185c324442b45c5107128325ef
Autor:
Yulei Wang, Carlos Bais, Lukas C. Amler, Ling Fu, Mark R. Lackner, Ling-Yuh Huw, Eloisa Fuentes, Shan Lu, Christina Rabe, Younjeong Choi, Yuanyuan Xiao, Ron Firestein, Yinghui Guan, Lisa Ryner
Purpose: Up to one third of ovarian cancer patients are intrinsically resistant to platinum-based treatment. However, predictive and therapeutic strategies are lacking due to a poor understanding of the underlying molecular mechanisms. This study aim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::443ebbbb567052a3114c0f2ed80b522f
https://doi.org/10.1158/1078-0432.c.6523293
https://doi.org/10.1158/1078-0432.c.6523293
Autor:
Yulei Wang, Lukas C. Amler, Garret M. Hampton, Rajesh Patel, Hartmut Koeppen, Lisa Ryner, Yinghui Guan, David Wang, Victor Weigman, Weiru Wang, Mark R. Lackner, Yibing Yan, Shan Lu, Richard Bourgon
XLSX file - 602KB, Supplementary Table 5. Cancer cell lines analyzed in this study. Supplementary Table 6. Tumor tissues analyzed in this study. Supplementary Table 7. List of 340 well characterized hotspot mutations interrogated by the amplicon libr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6dbd96c021dacf71bc9d034cc2f7ab5a
https://doi.org/10.1158/1078-0432.22454519.v1
https://doi.org/10.1158/1078-0432.22454519.v1
Autor:
Yulei Wang, Carlos Bais, Lukas C. Amler, Ling Fu, Mark R. Lackner, Ling-Yuh Huw, Eloisa Fuentes, Shan Lu, Christina Rabe, Younjeong Choi, Yuanyuan Xiao, Ron Firestein, Yinghui Guan, Lisa Ryner
Supplementary Tables S1-S7. This is a multi-"tabbed" Excel file containing the supplementary data of the manuscript and includes a "Summary" tab with descriptions/captions for the enclosed data sheets. They are as follows: Supplementary Table S1: 800
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fab2fa44fb86c3500e04345f3270e99
https://doi.org/10.1158/1078-0432.22456386.v1
https://doi.org/10.1158/1078-0432.22456386.v1
Autor:
Yulei Wang, Lukas C. Amler, Garret M. Hampton, Rajesh Patel, Hartmut Koeppen, Lisa Ryner, Yinghui Guan, David Wang, Victor Weigman, Weiru Wang, Mark R. Lackner, Yibing Yan, Shan Lu, Richard Bourgon
PDF file - 731KB, Supplementary Figure 1. Schematic workflow of MMP-seq. Supplementary Figure 2. Examples of tiling and hotspot amplicon designs. Supplementary Figure 3. Consistent target enrichment and variant allele quantification in FF biological
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e5b600cc79b6cd5a4a13f5b86059acb
https://doi.org/10.1158/1078-0432.22454522
https://doi.org/10.1158/1078-0432.22454522
Autor:
Yulei Wang, Carlos Bais, Lukas C. Amler, Ling Fu, Mark R. Lackner, Ling-Yuh Huw, Eloisa Fuentes, Shan Lu, Christina Rabe, Younjeong Choi, Yuanyuan Xiao, Ron Firestein, Yinghui Guan, Lisa Ryner
Supplementary Methods. Detailed methods descriptions for supplementary publication.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e7ae5b40c8c80e79f214ef961b89be0
https://doi.org/10.1158/1078-0432.22456389.v1
https://doi.org/10.1158/1078-0432.22456389.v1
Autor:
Yulei Wang, Lukas C. Amler, Garret M. Hampton, Rajesh Patel, Hartmut Koeppen, Lisa Ryner, Yinghui Guan, David Wang, Victor Weigman, Weiru Wang, Mark R. Lackner, Yibing Yan, Shan Lu, Richard Bourgon
Purpose: Tailoring cancer treatment to tumor molecular characteristics promises to make personalized medicine a reality. However, reliable genetic profiling of archived clinical specimens has been hindered by limited sensitivity and high false-positi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02982382b7a419cc0d88b388c9fbbde3
https://doi.org/10.1158/1078-0432.c.6522770.v1
https://doi.org/10.1158/1078-0432.c.6522770.v1
Autor:
Vincent Leveque, Shan Lu, Yulei Wang, YounJeong Choi, Oleg Mayba, Eric W. Humke, Sundari Sujathasarma, Yinghui Guan, Nga Wan Rachel Tam, Richard Bourgon, Anna Cheung, Lisa Ryner, Walter C. Darbonne, Thomas Sandmann, Mark R. Lackner
Publikováno v:
The Journal of Molecular Diagnostics. 19:921-932
Circulating tumor DNA (ctDNA) has potential to serve as a biomarker for noninvasive monitoring of treatment response and disease progression. However, broad clinical applicability of ctDNA has been limited by the low sensitivity, throughput, and pati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::970fdaae6c4ad301a0500682ac283e41
https://doi.org/10.1016/j.jmoldx.2017.08.001
https://doi.org/10.1016/j.jmoldx.2017.08.001
Autor:
Shan Lu, Shilpa Keerthivasan, Akshata Udyavar, Ching-Wei Chang, Anneleen Daemen, Hartmut Koeppen, Mélanie Desbois, Lisa Ryner, Yulei Wang, Richard Bourgon, Cleopatra Kozlowski, Priti S. Hegde, Yinghui Guan, Marie Plante, James Ziai, Carlos Bais, Jean-Philippe Fortin, Milena Dürrbaum, Shannon J. Turley
Publikováno v:
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Close proximity between cytotoxic T lymphocytes and tumour cells is required for effective immunotherapy. However, what controls the spatial distribution of T cells in the tumour microenvironment is not well understood. Here we couple digital patholo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02d2202783f6b8e4a690858debb33845
https://pubmed.ncbi.nlm.nih.gov/33149148
https://pubmed.ncbi.nlm.nih.gov/33149148
Publikováno v:
Genetics
Bruce Baker's laboratory made a huge impact on our understanding of Drosophila sex determination mechanisms. To celebrate these accomplishments, members of Bruce's laboratory describe the trailblazing science that led to mechanistic understanding of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13e66e3d30562dffaff7a98cd4d29e19
https://pubmed.ncbi.nlm.nih.gov/31167898
https://pubmed.ncbi.nlm.nih.gov/31167898