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of 3
pro vyhledávání: '"Lisa Rapalus"'
Autor:
Yoshiyuki Minegishi, Aubert Lavoie, Mary Ellen Conley, Charlotte Cunningham-Rundles, Lisa Rapalus
Publikováno v:
Clinical Immunology. 101:270-275
SWAP-70 is a recently identified protein that functions as the only B cell-specific component of an isotype switch recombination complex called SWAP. The SWAP complex has specificity for the switch regions upstream of the constant region immunoglobul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::273384e53aa701d1b8bff317b6cafe29
https://doi.org/10.1006/clim.2001.5116
https://doi.org/10.1006/clim.2001.5116
Publikováno v:
Immunological Reviews. 178:75-90
Patients with genetic defects in B-cell development provide an unusual opportunity to dissect the requirements for normal B-cell maturation. It is striking that all of the known genetic defects that result in a failure of B-cell development involve s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3c9c7e2ad3be74897e3f41112c90ac16
https://doi.org/10.1034/j.1600-065x.2000.17809.x
https://doi.org/10.1034/j.1600-065x.2000.17809.x
Autor:
Dario Campana, Lisa Rapalus, Mary Ellen Conley, Fügen Ersoy, Elaine Coustan-Smith, Yoshiyuki Minegishi
Publikováno v:
Journal of Clinical Investigation. 104:1115-1121
Mutations in Btk, mu heavy chain, or the surrogate light chain account for 85-90% of patients with early onset hypogammaglobulinemia and absent B cells. The nature of the defect in the remaining patients is unknown. We screened 25 such patients for m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c92dfbe5dbc24dd68932eebe239fe4f
https://doi.org/10.1172/jci7696
https://doi.org/10.1172/jci7696