Humanized TLR7/8 expression drives proliferative multisystemic histiocytosis in C57BL/6 mice.

Autor: Jessica M Snyder, Piper M Treuting, Lee Nagy, Cathy Yam, Jaehun Yi, Alicia Brasfield, Lisa Phuong Anh Nguyen, Adeline M Hajjar

Publikováno v: PLoS ONE, Vol 9, Iss 9, p e107257 (2014)

A humanized TLR7/TLR8 transgenic mouse line was engineered for studies using TLR7/8 ligands as vaccine adjuvants. The mice developed a spontaneous immune-mediated phenotype prior to six months of age characterized by runting, lethargy, blepharitis, a

Externí odkaz: https://doaj.org/article/90ba677b9f8549cda5fa2f8b33800789

List of Contributors

Autor: Eliana Abdelhay, Pavan P. Adiseshaiah, Massimo Aglietta, Maryline Allègra, Paolo A. Ascierto, Nuria Coll Bastus, Ahmed Basudan, A.M. Sofie Berghuis, Guido Biasco, Renata Binato, Ankita Borah, Janet E. Brown, Vera Cappelletti, Sock Hoai Chan, Alice P. Chen, Ru Chen, Maxime Chénard-Poirier, Nicoletta Chicchinelli, Mauro Cives, Pierfranco Conte, Stephany Corrêa, Raffaele Costanzo, Geraldine O’Sullivan Coyne, Massimo Cristofanilli, Maria Grazia Daidone, Franco Dammacco, Gennaro Daniele, Rosalba De Nola, Amélie Dendooven, Serena Di Cosimo, Massimo Di Maio, Maria Vittoria Dieci, Lorenzo D’Ambrosio, Stella D’Oronzo, Tanja Fehm, Francesca Fenizia, Paola Ferrari, Vikas Ghai, Mario Giuliano, Vinod Gopalan, Paolo Grassi, Giovanni Grignani, Valentina Guarneri, Rekha Gyanchandani, Simon Heeke, Paul Hofman, Véronique Hofman, Alessia Iannaccone, Marius Ilié, Farhadul Islam, Michele Iuliani, Richard Kennedy, Serguei Kozlov, D. Sakthi Kumar, Alfred King-Yin Lam, Rita Lampignano, Mattia Lauriola, Adrian V. Lee, Inyoul Lee, Patrizia Leone, Domenica Lovero, Yong-Jie Lu, Umberto Malapelle, Paolo Manca, Francesco Mannavola, Anna Manzo, Nuala McCabe, Svenja Meierjohann, Alessandra Merlini, Vasiliki Michalarea, Agnese Montanino, Alessandro Morabito, Margherita Nannini, Roman Nawroth, Hans Neubauer, Joanne Ngeow, Andrea Nicolini, Nicola Normanno, Raffaele Palmirotta, Giuliano Palumbo, Sheng Pan, Carolina Panis, Francesco Pantano, Eileen Parkes, Luigi Pasini, Anna Passarelli, Francesco Passiglia, Patrick Pauwels, Eleonora Pellè, Hong Peng, Francesco Perrone, Lisa Phuong, Maria Carmela Piccirillo, Richard Piekarz, Albrecht Piiper, Pasquale Pisapia, Nolan Priedigkeit, Michela Pucci, Davide Quaresmini, Richard Quek, Vito Racanelli, Anna Maria Rachiglio, Raffaele Ratta, Giulia Ribelli, Christian Rolfo, Joseph Ryan, Ahmad R. Safa, Roberto Salgado, Claudia Sandomenico, Dario Sangiolo, Daniele Santini, Francesco Schettini, Clorinda Schettino, Bastian Schilling, Jolanda J. Schoon, Alexei Shimanovsky, Erica Silvestris, Franco Silvestris, Sonia Simonetti, Elizabeth C. Smyth, Nagavalli Somasundaram, Kjetil Søreide, Jonathan Strosberg, Magdalena Swierczewska, Hideyuki Takeshima, Giuseppe Tonini, Toshikazu Ushijima, Angelo Vacca, Grazia Vernaci, Elena Verzoni, Eveline E. Vietsch, Bruno Vincenzi, Oliver Waidmann, Kai Wang, Xiaosheng Wang, Jeffery S. Wasser, Anton Wellstein, Steven L. Wood, Lei Xu, Harumi Yamada

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bf32e640eb3e94a6d33415a06aecb453
https://doi.org/10.1016/b978-0-12-811785-9.00053-3

The effect of everolimus on body composition (BC) in patients with metastatic breast cancer (MBC)

Autor: Janki Patel, Jesus Del Santo Anampa Mesias, Michael Lyudmer, Stephanie Shamir, Lisa Phuong, Junwen Deng, Nadia Baka, Jessica Goldman, Alvaro Alvarez Soto

Publikováno v: Journal of Clinical Oncology. 39:e13026-e13026

e13026 Background: BC measurement can distinguish adipose tissue distribution, as well as the quantity and quality of muscle. Dysregulation in the mammalian target of rapamycin (mTOR) signaling pathway is associated with obesity and its related disea

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::eb1e6a8434bf716dd1f78b20660c4d16
https://doi.org/10.1200/jco.2021.39.15_suppl.e13026

Long-term impact of patient navigation (PN) for breast cancer (BCA) screening in an urban academic medical center

Autor: Jesus Del Santo Anampa Mesias, Della F. Makower, Melanie Lozada, Lisa Phuong

Publikováno v: Journal of Clinical Oncology. 38:130-130

130 Background: PN improves BCA screening rates in underserved women, and decreases health care disparities. However, there is limited data regarding the ability of PN effect sustained change. We evaluated the long-term impact of PN for BCA screening

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1f93e85e10b13c88efd13136b7942e3f
https://doi.org/10.1200/jco.2020.38.29_suppl.130

A nonrandomized study on compliance with IDSA guidelines on the choice and dosing of empiric antibiotics for patients with febrile neutropenia after implementation of a new Computerized Physician Order Entry (CPOE)

Autor: Edward Belk Perry, Kapil Meleveedu, Lisa Phuong, Susan Tannenbaum, Sai Kaza

Publikováno v: Journal of Clinical Oncology. 36:48-48

48 Background: More than 80% of patients with hematologic malignancies and 10-50% of patients with solid tumors are expected to experience fever after one cycle of chemotherapy. Studies have shown all-cause mortality to be 15% higher in cancer patien

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e8eda7365937874ea8bfa2a1f8bbf0f1
https://doi.org/10.1200/jco.2018.36.30_suppl.48