Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Lisa Philp"'
Autor:
Anja Rockstroh, John D. Wade, Colleen C. Nelson, Martin C. Sadowski, Laszlo Otvos, Nenad Bartonicek, Melanie Lehman, Lisa Philp
Publikováno v:
Endocrine-Related Cancer. 27:711-729
Adiponectin is an adipokine originally identified as dysregulated in obesity, with a key role in insulin sensitisation and in maintaining systemic energy balance. However, adiponectin is progressively emerging as having aberrant signalling in multipl
Autor:
Kaylyn D. Tousignant, Stephen J. Blanksby, Ron M. A. Heeren, Jennifer H. Gunter, Reuben S. E. Young, Lisa Philp, Shane R. Ellis, Berwyck L. J. Poad, Martin C. Sadowski, Andrew P. Bowman, Colleen C. Nelson
1.0SummaryCellular energy and biomass demands of cancer drive a complex dynamic between uptake of extracellular fatty acids (FA) and de novo synthesis. Given that oxidation of de novo synthesised FAs for energy would result in net-energy loss, there
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c72b6552667db3bc8163fe480b071bdd
https://doi.org/10.1101/2021.11.01.466716
https://doi.org/10.1101/2021.11.01.466716
Autor:
Stephen McPherson, Marcel E. Dinger, Chenwei Wang, Martin C. Sadowski, Kaylyn D. Tousignant, Anja Rockstroh, Atefeh Taherian Fard, Lisa Philp, Nenad Bartonicek, Colleen C. Nelson, Melanie Lehman
Publikováno v:
Molecular Cancer Research. 17:1166-1179
De novo lipogenesis is a well-described androgen receptor (AR)–regulated metabolic pathway that supports prostate cancer tumor growth by providing fuel, membrane material, and steroid hormone precursor. In contrast, our current understanding of lip
Autor:
Charles L. Bidgood, Michelle S. Libério, Martin C. Sadowski, Melanie Lehman, Colleen C. Nelson, John D. Wade, Jennifer H. Gunter, Lisa Philp, Anja Rockstroh, Stephen McPherson, Laszlo Otvos, Gregor Tevz, Nenad Bartonicek, Atefeh Taherian Fard
Publikováno v:
Philp, Lisa K; Rockstroh, Anja; Sadowski, Martin C; Taherian Fard, Atefeh; Lehman, Melanie; Tevz, Gregor; Libério, Michelle S; Bidgood, Charles L; Gunter, Jennifer H; McPherson, Stephen; Bartonicek, Nenad; Wade, John D; Otvos, Laszlo; Nelson, Colleen C (2021). Leptin antagonism inhibits prostate cancer xenograft growth and progression. Endocrine-related cancer, 28(5), pp. 353-375. BioScientifica Ltd. 10.1530/ERC-20-0405
Hyperleptinaemia is a well-established therapeutic side effect of drugs inhibiting the androgen axis in prostate cancer (PCa), including main stay androgen deprivation therapy (ADT) and androgen targeted therapies (ATT). Given significant crossover b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67ea4121f76d184e85e5e2e7dda6b1d9
https://boris.unibe.ch/161800/1/33794502.pdf
https://boris.unibe.ch/161800/1/33794502.pdf
Characterization of the utility of three nebulizers in investigating infectivity of airborne viruses
Laboratory-generated bioaerosols are widely used in aerobiology studies of viruses, however few comparisons of alternative nebulizers exist. We compared aerosol production and virus survival for a Collison nebulizer, vibrating mesh nebulizer (VMN), a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5254f464dcc8bd436724ad677e8ec3c6
https://doi.org/10.1101/2021.03.11.435057
https://doi.org/10.1101/2021.03.11.435057
Publikováno v:
Endocrine Reviews. 38:i1-i1431
Autor:
Brett G. Hollier, Tiffany Tang, Esha T. Shah, Akanksha Upadhyaya, Elizabeth D. Williams, Dubravka Skalamera, Lisa Philp, Colleen C. Nelson, Jennifer H. Gunter
Publikováno v:
Clinical & Experimental Metastasis. 33:385-399
The majority of prostate cancer (PCa) deaths occur due to the metastatic spread of tumor cells to distant organs. Currently, there is a lack of effective therapies once tumor cells have spread outside the prostate. It is therefore imperative to rapid
Autor:
Penny L. Jeffery, Chen Chen, Laura S. Gregory, Michelle Maugham, Inge Seim, Lisa K. Chopin, Lisa Philp, Esha T. Shah, Colleen C. Nelson, Patrick Thomas, Adrian C. Herington, Gabrielle Crisp
Publikováno v:
Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Hyperinsulinaemia, obesity and dyslipidaemia are independent and collective risk factors for many cancers. Here, the long-term effects of a 23% Western high-fat diet (HFD) in two immunodeficient mouse strains (NOD/SCID and Rag1−/−) suitable for e
Publikováno v:
Endocrine Reviews. 35:i1-i1153
Autor:
Richard L. Young, L. Ashley Blackshaw, Hui Li, Tracey A. O'Donnell, Amanda J. Page, Nicole J. Isaacs, Stephen J. Kentish, Gary A. Wittert, Lisa Philp
Publikováno v:
The Journal of Physiology. 590:209-221
Afferent signals from the stomach play an important role in inhibition of food intake during a meal. The gastric hormone ghrelin can influence gastric satiety signalling by altering the sensitivity of gastric vagal afferents. Changes in diet, includi