Zobrazeno 1 - 9 of 9 pro vyhledávání: '"Lisa Pechtold"'
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Akademický článek
Early IL-10 producing B-cells and coinciding Th/Tr17 shifts during three year grass-pollen AITResearch in context
Autor: Ulrich M. Zissler, Constanze A. Jakwerth, Ferdinand M. Guerth, Lisa Pechtold, Juan Antonio Aguilar-Pimentel, Katharina Dietz, Kathrin Suttner, Guido Piontek, Bernhard Haller, Zuzana Hajdu, Matthias Schiemann, Carsten B. Schmidt-Weber, Adam M. Chaker
Publikováno v: EBioMedicine, Vol 36, Iss , Pp 475-488 (2018)
Background: Allergen-specific immunotherapy (AIT) is a causative treatment in allergic airway disease, comprising long-term allergen administration and requiring three years of treatment. Mechanisms and biomarkers that translate into clinical efficac
Externí odkaz: https://doaj.org/article/8745664df04b40409aa0082b5e9a8c7a
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2
An exhausted phenotype of T H 2 cells is primed by allergen exposure, but not reinforced by allergen‐specific immunotherapy
Autor: Carsten Schmidt-Weber, Sebastian Kotz, Adam Chaker, Mirjam Plaschke, Shu-Hung Wang, Ferdinand Guerth, Sonja Heine, Alexander Heldner, Julia T Ullmann, Maren Buettner, Francesca Alessandrini, Ulrich M. Zissler, Lisa Pechtold, Constanze A. Jakwerth, Simon Blank, Josephine Kau, Madlen Oelsner
Publikováno v: Allergy 76, 2827-2839 (2021)
BACKGROUND Studies show that proallergic TH 2 cells decrease after successful allergen-specific immunotherapy (AIT). It is likely that iatrogenic administration of allergens drives these cells to exhaustion due to chronic T-cell receptor stimulation.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b37bb7265f1742336a233f75dda4c14
https://doi.org/10.1111/all.14896
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4
Early reduction of SARS-CoV-2-replication in bronchial epithelium by kinin B
Autor: Constanze A, Jakwerth, Martin, Feuerherd, Ferdinand M, Guerth, Madlen, Oelsner, Linda, Schellhammer, Johanna, Giglberger, Lisa, Pechtold, Claudia, Jerin, Luisa, Kugler, Carolin, Mogler, Bernhard, Haller, Anna, Erb, Barbara, Wollenberg, Christoph D, Spinner, Thorsten, Buch, Ulrike, Protzer, Carsten B, Schmidt-Weber, Ulrich M, Zissler, Adam M, Chaker
Publikováno v: Journal of molecular medicine (Berlin, Germany). 100(4)
SARS-CoV-2 has evolved to enter the host via the ACE2 receptor which is part of the kinin-kallikrein pathway. This complex pathway is only poorly understood in context of immune regulation but critical to control infection. This study examines SARS-C
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::75477a5af1706346bd946ff950eb24e4
https://pubmed.ncbi.nlm.nih.gov/35247068
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5
Early Reduction of SARS-CoV-2 Replication in Bronchial Epithelium by Kinin B2 Receptor Antagonism
Autor: Constanze A. Jakwerth, Anna Erb, Ferdinand Guerth, Christoph D. Spinner, Lisa Pechtold, Carolin Mogler, Adam Chaker, Linda Schellhammer, Carsten B. Schmidt-Weber, Thorsten Buch, Luisa Kugler, Barbara Wollenberg, Madlen Oelsner, Ulrike Protzer, Martin Feuerherd, Claudia Jerin, Ulrich M. Zissler, Bernhard Haller, Johanna Giglberger
Publikováno v: J. Mol. Med. 100, 613-627 (2022)
Abstract SARS-CoV-2 has evolved to enter the host via the ACE2 receptor which is part of the kinin-kallikrein pathway. This complex pathway is only poorly understood in context of immune regulation but critical to control infection. This study examin
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e62db847e037942752e05e692cd8e26
https://doi.org/10.1101/2021.08.13.21262037
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6
An exhausted phenotype of T
Autor: Shu-Hung, Wang, Ulrich M, Zissler, Maren, Buettner, Sonja, Heine, Alexander, Heldner, Sebastian, Kotz, Lisa, Pechtold, Josephine, Kau, Mirjam, Plaschke, Julia T, Ullmann, Ferdinand, Guerth, Madlen, Oelsner, Francesca, Alessandrini, Simon, Blank, Adam M, Chaker, Carsten B, Schmidt-Weber, Constanze A, Jakwerth
Publikováno v: AllergyREFERENCES. 76(9)
Studies show that proallergic TOVA-sensitized C57BL/6J mice were challenged and treated with OVA, and the development of exhaustion in local and systemic TThe exhaustion-associated surface markers CTLA-4 and PD-1 were significantly upregulated on TTh
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ac1600a0297d8d282c88efd823687825
https://pubmed.ncbi.nlm.nih.gov/33969495
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8
Sputum microRNA‐screening reveals Prostaglandin EP3 receptor as selective target in allergen‐specific immunotherapy
Autor: Antonia Kloss, Susanne Krauss-Etschmann, Adam Chaker, Ulrich M. Zissler, Julia T. Ullmann, Anna Erb, Madlen Oelsner, Julia Esser-von Bieren, Alexandra Kurz, Carsten B. Schmidt-Weber, Ferdinand Guerth, Constanze A. Jakwerth, Lynn S Zur Bonsen, Marlene Winkler, Mirjam Plaschke, Lisa Pechtold, Josephine Kau
Publikováno v: Clin. Exp. Allergy, DOI: 10.1111/cea.14013 (2021)
BACKGROUND Several microRNAs (miRs) have been described as potential biomarkers in liquid biopsies and in the context of allergic asthma, while therapeutic effects on the airway expression of miRs remain elusive. In this study, we investigated epigen
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71310099098bdee2778f7af49d9a322b
https://mediatum.ub.tum.de/doc/1654767/document.pdf
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9
Early IL-10 producing B-cells and coinciding Th/Tr17 shifts during three year grass-pollen AIT
Autor: Bernhard Haller, Katharina Dietz, Guido Piontek, Zuzana Hajdu, Adam Chaker, Kathrin Suttner, Carsten B. Schmidt-Weber, Lisa Pechtold, Constanze A. Jakwerth, Juan Antonio Aguilar-Pimentel, Matthias Schiemann, Ulrich M. Zissler, Ferdinand Guerth
Publikováno v: EBioMedicine
EBioMedicine 36, 475-488 (2018)
Background Allergen-specific immunotherapy (AIT) is a causative treatment in allergic airway disease, comprising long-term allergen administration and requiring three years of treatment. Mechanisms and biomarkers that translate into clinical efficacy
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42ae05199c427a1e20c31b23d1f99b28
https://mediatum.ub.tum.de/doc/1489355/document.pdf
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