Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Lisa Ostyn"'
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 6 (2024)
ABSTRACT Cystic fibrosis (CF), an inherited genetic disorder caused by mutations in the cystic fibrosis transmembrane conductance regulator gene, results in sticky and thick mucosal fluids. This environment facilitates the colonization of various mic
Externí odkaz:
https://doaj.org/article/d04d9a88b23d4e7eaea4c85ab362a6b5
Autor:
Fien Gysens, Lisa Ostyn, Ellen Goeteyn, Eva Blondeel, Justine Nuyttens, Olivier De Wever, Eric de Bony, Aurélie Crabbé, Pieter Mestdagh
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-7 (2023)
Abstract In vitro cell culture experiments are widely used to study cellular behavior in most biological research fields. Except for suspension cells, most human cell types are cultured as adherent monolayers on a plastic surface. While technically c
Externí odkaz:
https://doaj.org/article/4dc19f017dc749a4983a18249c8d1f0e
Autor:
Frits van Charante, Anneleen Wieme, Petra Rigole, Evelien De Canck, Lisa Ostyn, Lucia Grassi, Dieter Deforce, Aurélie Crabbé, Peter Vandamme, Marie Joossens, Filip Van Nieuwerburgh, Pieter Depuydt, Tom Coenye
Publikováno v:
Biofilm, Vol 4, Iss , Pp 100079- (2022)
In patients with acute respiratory failure, mechanical ventilation through an endotracheal tube (ET) may be required to correct hypoxemia and hypercarbia. However, biofilm formation on these ETs is a risk factor for infections in intubated patients,
Externí odkaz:
https://doaj.org/article/a2b4d62859b141cfa545e695daf78ce0
Autor:
Eva Vandeplassche, Andrea Sass, Lisa Ostyn, Mette Burmølle, Kasper Nørskov Kragh, Thomas Bjarnsholt, Tom Coenye, Aurélie Crabbé
Publikováno v:
Biofilm, Vol 2, Iss , Pp 100031- (2020)
The lungs of cystic fibrosis (CF) patients are often chronically colonized by multiple microbial species that can form biofilms, including the major CF pathogen Pseudomonas aeruginosa. Herewith, lower microbial diversity in CF airways is typically as
Externí odkaz:
https://doaj.org/article/ffaf43ec9e0c406cac41b86c8796a836
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 10 (2020)
Models to study host-pathogen interactions in vitro are an important tool for investigating the infectious disease process and evaluating the efficacy of antimicrobial compounds. In these models, the viability of mammalian cells is often determined u
Externí odkaz:
https://doaj.org/article/aaa4ae38c42642eea966f2ac1927837d
Autor:
Heleen Van Acker, Aurélie Crabbé, Dukas Jurėnas, Lisa Ostyn, Andrea Sass, Simon Daled, Maarten Dhaenens, Dieter Deforce, Eline Teirlinck, Herlinde De Keersmaecker, Kevin Braeckmans, Laurence Van Melderen, Tom Coenye
Publikováno v:
Biofilm, Vol 1, Iss , Pp - (2019)
Burkholderia cenocepacia infections are difficult to treat due to resistance, biofilm formation and persistence. B. cenocepacia strain J2315 has a large multi-replicon genome (8.06 Mb) and the function of a large fraction of (conserved) hypothetical
Externí odkaz:
https://doaj.org/article/1813f374099d49bba0e33d369f424955
Autor:
Aurélie Crabbé, Lisa Ostyn, Sorien Staelens, Charlotte Rigauts, Martijn Risseeuw, Maarten Dhaenens, Simon Daled, Heleen Van Acker, Dieter Deforce, Serge Van Calenbergh, Tom Coenye
Publikováno v:
PLoS Pathogens, Vol 15, Iss 4, p e1007697 (2019)
Antibiotic susceptibility of bacterial pathogens is typically evaluated using in vitro assays that do not consider the complex host microenvironment. This may help explaining a significant discrepancy between antibiotic efficacy in vitro and in vivo,
Externí odkaz:
https://doaj.org/article/2706a68c47b6435aaafd17978aab5542
Autor:
Lucia Grassi, Giovanna Batoni, Lisa Ostyn, Petra Rigole, Sara Van den Bossche, Andrea C. Rinaldi, Giuseppantonio Maisetta, Semih Esin, Tom Coenye, Aurélie Crabbé
Publikováno v:
Frontiers in Microbiology, Vol 10 (2019)
Antimicrobial peptides (AMPs) are promising templates for the development of novel antibiofilm drugs. Despite the large number of studies on screening and optimization of AMPs, only a few of these evaluated the antibiofilm activity in physiologically
Externí odkaz:
https://doaj.org/article/9d96755c888b4e02a630253e5d0f231e
Autor:
Fien Gysens, Lisa Ostyn, Ellen Goeteyn, Justine Nuyttens, Eric de Bony de Lavergne, Aurélie Crabbé, Pieter Mestdagh
In vitro cell culture experiments are widely used to study cellular behavior in most biological research fields. Except for suspension cells, most human cell types are cultured as adherent monolayers on a plastic surface. While technically convenient
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::309e8cd7af400b5141f37821e9973a36
https://doi.org/10.22541/au.165700624.40692093/v1
https://doi.org/10.22541/au.165700624.40692093/v1
Autor:
Juliana Aizawa, Aurélie Crabbé, Lisa Ostyn, Charlotte Rigauts, Michael M. Tunney, Paul Cos, Lucy D. Burr, Jodie L. Simpson, Heleen Van Acker, Cristina Cigana, Lars Vereecke, Anne Willems, Matthias Govaerts, Tom Coenye, Mozes Sze, Eva Vandeplassche, Geraint B. Rogers, Steven L. Taylor, Alessandra Bragonzi, Sarah K. Sims, Yves Dondelinger
Publikováno v:
The European respiratory journal
EUROPEAN RESPIRATORY JOURNAL
Rigauts, C, Aizawa, J, Taylor, S, Rogers, G B, Govaerts, M, Cos, P, Ostyn, L, Sims, S, Vandeplassche, E, Sze, M, Dondelinger, Y, Vereecke, L, Van Acker, H, Simpson, J L, Burr, L, Willems, A, Tunney, M M, Cigana, C, Bragonzi, A, Coenye, T & Crabbé, A 2022, ' Rothia mucilaginosa is an anti-inflammatory bacterium in the respiratory tract of patients with chronic lung disease ', European Respiratory Journal, vol. 59, no. 5 . https://doi.org/10.1183/13993003.01293-2021
EUROPEAN RESPIRATORY JOURNAL
Rigauts, C, Aizawa, J, Taylor, S, Rogers, G B, Govaerts, M, Cos, P, Ostyn, L, Sims, S, Vandeplassche, E, Sze, M, Dondelinger, Y, Vereecke, L, Van Acker, H, Simpson, J L, Burr, L, Willems, A, Tunney, M M, Cigana, C, Bragonzi, A, Coenye, T & Crabbé, A 2022, ' Rothia mucilaginosa is an anti-inflammatory bacterium in the respiratory tract of patients with chronic lung disease ', European Respiratory Journal, vol. 59, no. 5 . https://doi.org/10.1183/13993003.01293-2021
BackgroundChronic airway inflammation is the main driver of pathogenesis in respiratory diseases such as severe asthma, chronic obstructive pulmonary disease, cystic fibrosis (CF) and bronchiectasis. While the role of common pathogens in airway infla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a8dd902fcac75cecf4e53410d0f9e1f
https://hdl.handle.net/10067/1882970151162165141
https://hdl.handle.net/10067/1882970151162165141