Double subgenomic alphaviruses expressing multiple fluorescent proteins using a Rhopalosiphum padi virus internal ribosome entry site element.

Autor: Michael R Wiley, Lisa O Roberts, Zach N Adelman, Kevin M Myles

Publikováno v: PLoS ONE, Vol 5, Iss 11, p e13924 (2010)

Double subgenomic Sindbis virus (dsSINV) vectors are widely used for the expression of proteins, peptides, and RNA sequences. These recombinant RNA viruses permit high level expression of a heterologous sequence in a wide range of animals, tissues, a

Externí odkaz: https://doaj.org/article/e1b691a6eb4542668cc214778db814e2

Type I and III IFNs Produced by Plasmacytoid Dendritic Cells in Response to a Member of the Flaviviridae Suppress Cellular Immune Responses

Autor: Gregor Meyers, Elizabeth Reid, Miriam Windsor, Sophie B. Morgan, Simon Gubbins, Elma Tchilian, Julian Seago, Nicholas Juleff, Bryan Charleston, Lisa O. Roberts, Eva Pérez-Martín

Publikováno v: The Journal of Immunology. 196:4214-4226

The pestivirus noncytopathic bovine viral diarrhea virus (BVDV) can suppress IFN production in the majority of cell types in vitro. However, IFN is detectable in serum during acute infection in vivo for ∼5–7 d, which correlates with a period of l

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05d14cbc1621bfb77254c708e32b0f37
https://doi.org/10.4049/jimmunol.1600049

Distinct roles for the IIId2 sub-domain in pestivirus and picornavirus internal ribosome entry sites

Autor: Salmah Zaini, Bruno Sargueil, Johanne Hadsbjerg, Nathalie Ulryck, Graham J. Belsham, Delphine Allouche, Margaret M. Willcocks, Noemie Rajagopalan, Nana A. Davids, Ulrik Fahnøe, Nicolas Locker, Thomas Bruun Rasmussen, Nathalie Chamond, Lisa O. Roberts

Publikováno v: Nucleic Acids Research
Nucleic Acids Research, Oxford University Press, 2017, 45 (22), pp.13016-13028. ⟨10.1093/nar/gkx991⟩
Willcocks, M M, Zaini, S, Chamond, N, Ulryck, N, Allouche, D, Rajagopalan, N, Davids, N A, Fahn E, U, Hadsbjerg, J, Rasmussen, T B, Roberts, L O, Sargueil, B, Belsham, G J & Locker, N 2017, ' Distinct roles for the IIId2 sub-domain in pestivirus and picornavirus internal ribosome entry sites ', Nucleic Acids Research, vol. 2017, gkx991 . https://doi.org/10.1093/nar/gkx991

Viral internal ribosomes entry site (IRES) elements coordinate the recruitment of the host translation machinery to direct the initiation of viral protein synthesis. Within hepatitis C virus (HCV)-like IRES elements, the sub-domain IIId(1) is crucial

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fa5590fc41463f7d84386c2d9b73c62
https://pubmed.ncbi.nlm.nih.gov/29069411

Design and application of a loop-mediated isothermal amplification assay for the rapid detection of Staphylococcus pseudintermedius

Autor: Onyinye Diribe, Sarah North, Lisa O. Roberts, Roberto M. La Ragione, Jason Sawyer, Noel Fitzpatrick

Publikováno v: Journal of Veterinary Diagnostic Investigation. 26:42-48

Staphylococcus pseudintermedius is a commensal and opportunistic pathogen of dogs. It is mainly implicated in canine pyoderma, as well as other suppurative conditions of dogs. Although bacterial culture is routinely used for clinical diagnosis, molec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfefa7c23ecd7551aece34383f9eb75f
https://doi.org/10.1177/1040638713516758

Murine norovirus-1 cell entry is mediated through a non-clathrin-, non-caveolae-, dynamin- and cholesterol-dependent pathway

Autor: Paul Monaghan, Nicole Doyle, Lisa O. Roberts, Andreas Gerondopoulos, Terry Jackson

Publikováno v: Journal of General Virology. 91:1428-1438

For many viruses, endocytosis and exposure to the low pH within acidic endosomes is essential for infection. It has previously been reported that feline calicivirus uses clathrin-mediated endocytosis for entry into mammalian cells. Here, we report th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c11af6fd575cc34a280f76ad575b2da1
https://doi.org/10.1099/vir.0.016717-0