Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Lisa Nip"'
Autor:
Deanna G. Brockman, Lia Petronio, Jacqueline S. Dron, Bum Chul Kwon, Trish Vosburg, Lisa Nip, Andrew Tang, Mary O’Reilly, Niall Lennon, Bang Wong, Kenney Ng, Katherine H. Huang, Akl C. Fahed, Amit V. Khera
Publikováno v:
BMC Medical Genomics, Vol 14, Iss 1, Pp 1-20 (2021)
Abstract Background Polygenic scores—which quantify inherited risk by integrating information from many common sites of DNA variation—may enable a tailored approach to clinical medicine. However, alongside considerable enthusiasm, we and others h
Externí odkaz:
https://doaj.org/article/59218b19588f4237b182b1d2355f462d
Autor:
Pranam Chatterjee, Jooyoung Lee, Lisa Nip, Sabrina R. T. Koseki, Emma Tysinger, Erik J. Sontheimer, Joseph M. Jacobson, Noah Jakimo
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-6 (2020)
Protospacer adjacent motif (PAM) requirements limit the target range of CRISPR endonucleases. Here, the authors graft the 5$$^{\prime}$$ ′ -NAAN-3$$^{\prime}$$ ′ PAM-interacting domain of SmacCas9 onto SpyCas9 to create adenine dinucleotide targe
Externí odkaz:
https://doaj.org/article/de6c445336ca4aacb34b61cb8daeb358
Autor:
Lia Petronio, Bum Chul Kwon, Mary O'Reilly, Kenney Ng, Trish Vosburg, Amit Khera, Lisa Nip, Bang Wong, Niall J. Lennon, Deanna Brockman, Jacqueline S. Dron, Akl C. Fahed, Katherine H. Huang, Andrew Tang
Publikováno v:
BMC Medical Genomics, Vol 14, Iss 1, Pp 1-20 (2021)
BMC Medical Genomics
BMC Medical Genomics
BackgroundPolygenic scores—which quantify inherited risk by integrating information from many common sites of DNA variation—may enable a tailored approach to clinical medicine. However, alongside considerable enthusiasm, we and others have highli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1589c51e8f41bd42038c15e8fd6ddfcb
https://doaj.org/article/59218b19588f4237b182b1d2355f462d
https://doaj.org/article/59218b19588f4237b182b1d2355f462d
Autor:
Mollie Jurewicz, Elizabeth Hall, Alexandra Luther, Kimberly Cirelli, Vivin Karthik, Kenneth Jahan, Tary Traore, Maytal Bowman, Victor Ospina, Sonal Jangalwe, Shubhangi Kamalia, Sadie Lee, Daniel Pollacksmith, Sida Liao, Amy Virbasius, Kristen Murray, Jillian Oliveira, Lisa Nip, Christina Lam, Livio Dukaj, Danielle Ramsdell, Jin He, Joel Sher, Ribhu Nayar, Qikai Xu, Yifan Wang, Antoine Boudot, Cagan Gurer, Gavin MacBeath
Publikováno v:
Regular and Young Investigator Award Abstracts.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::13e4f9d5db335721908b9c2d73ac06e8
https://doi.org/10.1136/jitc-2022-sitc2022.0182
https://doi.org/10.1136/jitc-2022-sitc2022.0182
Autor:
Erik J. Sontheimer, Emma Tysinger, Noah Jakimo, Jooyoung Lee, Pranam Chatterjee, Lisa Nip, Sabrina R. T. Koseki, Joseph M. Jacobson
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-6 (2020)
Nature Communications
Nature Communications
CRISPR-associated (Cas) DNA-endonucleases are remarkably effective tools for genome engineering, but have limited target ranges due to their protospacer adjacent motif (PAM) requirements. We demonstrate a critical expansion of the targetable sequence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a6b5a0c27a1c6be40ec57067e1cd2e6
http://link.springer.com/article/10.1038/s41467-020-16117-8
http://link.springer.com/article/10.1038/s41467-020-16117-8
Autor:
Katherine H. Huang, Mary O'Reilly, Amit Khera, Lia Petronio, Kenney Ng, Lisa Nip, Jacqueline S. Dron, Trish Vosburg, Bum Chul Kwon, Deanna Brockman, Niall J. Lennon, Akl C. Fahed, Andrew Tang, Bang Wong
BackgroundPolygenic scores – which quantify inherited risk by integrating information from many common sites of DNA variation – may enable a tailored approach to clinical medicine. However, alongside considerable enthusiasm, we and others have hi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e4550f05cf4c0395ed3a1700c9535f7b
https://doi.org/10.1101/2021.04.14.21255397
https://doi.org/10.1101/2021.04.14.21255397
Autor:
Krista Daniel, Shrikanta Chattopadhyay, Kenneth N. Olivier, Alexandra Luther, Cisem Karaca, Gavin MacBeath, Yifan Wang, Livio Dukaj, Antoine Boudot, Amy Virbasius, Alexandra Cristofaro, Cagan Gurer, Andrew Basinski, Daniel Pollacksmith, Kenneth L Jahan, Qikai Xu, Danielle Ramsdell, Hannah L. Bader, Mollie M Jurewicz, Ribhu Nayar, Candace R. Perullo, Sida Liao, Kimberly M Cirelli, Lisa Nip, Sonal Jangalwe, Anna Labrozzi
Publikováno v:
Blood. 138:1704-1704
Background Approximately 50% of AML patients relapse following allogeneic hematopoietic stem cell transplant therapy, leaving them with very few treatment options (Rautenberg et al. (2019) Int. J. Mol. Sci. 20:228). Rare patients who naturally develo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dd6a9c3930ac8c4538d30f984febbf16
https://doi.org/10.1182/blood-2021-151317
https://doi.org/10.1182/blood-2021-151317
CRISPR-associated (Cas) DNA-endonucleases are remarkably effective tools for genome engineering, but have limited target ranges due to their protospacer adjacent motif (PAM) requirements. We demonstrate a critical expansion of the targetable sequence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::436438b313b2c787ceb8537bef82b8c1
Publikováno v:
Nature methods
We report an approach to barcode cells through cell-surface expression of programmable zinc-finger DNA-binding domains (surface zinc fingers, sZFs). We show that sZFs enable sequence-specific labeling of living cells by dsDNA, and we develop a sequen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1209707ff23a41e2d58e867f6d2113b
http://europepmc.org/articles/PMC3641172
http://europepmc.org/articles/PMC3641172