Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Lisa Nieland"'
Autor:
Taral R. Lunavat, Lisa Nieland, Anne B. Vrijmoet, Ayrton Zargani-Piccardi, Youssef Samaha, Koen Breyne, Xandra O. Breakefield
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Glioblastoma (GB) tumors are one of the most insidious cancers which take over the brain and defy therapy. Over time and in response to treatment the tumor and the brain cells in the tumor microenvironment (TME) undergo many genetic/epigenetic driven
Externí odkaz:
https://doaj.org/article/0e251dfaf2a44f69a4e83d6aa98cd6b4
Autor:
Lisa Nieland, Thomas S. van Solinge, Pike See Cheah, Liza M. Morsett, Joseph El Khoury, Joseph I. Rissman, Benjamin P. Kleinstiver, Marike L.D. Broekman, Xandra O. Breakefield, Erik R. Abels
Publikováno v:
Molecular Therapy: Oncolytics, Vol 25, Iss , Pp 121-136 (2022)
Non-coding RNAs, including microRNAs (miRNAs), support the progression of glioma. miR-21 is a small, non-coding transcript involved in regulating gene expression in multiple cellular pathways, including the regulation of proliferation. High expressio
Externí odkaz:
https://doaj.org/article/e7f869deba594a7dad62253d7bf25498
Autor:
Erik R. Abels, Sybren L.N. Maas, Lisa Nieland, Zhiyun Wei, Pike See Cheah, Eric Tai, Christy-Joy Kolsteeg, Sophie A. Dusoswa, David T. Ting, Suzanne Hickman, Joseph El Khoury, Anna M. Krichevsky, Marike L.D. Broekman, Xandra O. Breakefield
Publikováno v:
Cell Reports, Vol 28, Iss 12, Pp 3105-3119.e7 (2019)
Summary: Gliomas are primary, diffusely infiltrating brain tumors. Microglia are innate immune cells in the CNS and make up a substantial portion of the tumor mass. Glioma cells shape their microenvironment, communicating with and reprogramming surro
Externí odkaz:
https://doaj.org/article/77fbde4a03344664a5847ccb72526d8d
Autor:
Erik R. Abels, Lisa Nieland, Suzanne Hickman, Marike L. D. Broekman, Joseph El Khoury, Sybren L. N. Maas
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 3, p 1495 (2021)
One of the essential functions of microglia is to continuously sense changes in their environment and adapt to those changes. For this purpose, they use a set of genes termed the sensome. This sensome is comprised of the most abundantly expressed rec
Externí odkaz:
https://doaj.org/article/c9ee62ce17de4db48c7551894549f8b7
Publikováno v:
Journal of Controlled Release. 356:493-506
A recent Nature Medicine article reported a phase II single-arm trial assessing the efficacy of a triple-mutated, third-generation oncolytic herpes simplex virus type 1 in patients with recurrent or residual glioblastoma. We discuss the results and h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca67dd4d40c3f9ae311fefed8db6ad20
https://hdl.handle.net/1887/3512677
https://hdl.handle.net/1887/3512677
Publikováno v:
Nature Reviews Neurology, 18(4), 221-236. NATURE PORTFOLIO
Despite advances in neurosurgery, chemotherapy and radiotherapy, glioblastoma remains one of the most treatment-resistant CNS malignancies, and the tumour inevitably recurs. The majority of recurrences appear in or near the resection cavity, usually
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53ab37bc352fbd357b7959693dfb9998
https://hdl.handle.net/1887/3570535
https://hdl.handle.net/1887/3570535
Publikováno v:
Nature reviews. Neurology. 18(4)
Despite advances in neurosurgery, chemotherapy and radiotherapy, glioblastoma remains one of the most treatment-resistant CNS malignancies, and the tumour inevitably recurs. The majority of recurrences appear in or near the resection cavity, usually
Publikováno v:
Trends Neurosci
Trends in Neurosciences, 44(3), 215-226. ELSEVIER SCIENCE LONDON
Trends in Neurosciences, 44(3), 215-226. ELSEVIER SCIENCE LONDON
Glioblastoma the most aggressive form of brain cancer, comprises a complex mixture of tumor cells and nonmalignant stromal cells, including neurons, astrocytes, microglia, infiltrating monocytes/macrophages, lymphocytes, and other cell types. All non
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2349e2a5bf07e0b0ff494ccbb79390e0
https://hdl.handle.net/1887/3196152
https://hdl.handle.net/1887/3196152
Autor:
Pike See Cheah, Xandra O. Breakefield, David T. Ting, Zhiyun Wei, Joseph El Khoury, Marike L. D. Broekman, Lisa Nieland, Anna M. Krichevsky, Sybren L. N. Maas, Suzanne E. Hickman, Erik R. Abels, Eric Tai, Sophie A. Dusoswa, Christy Joy Kolsteeg
Publikováno v:
Cell reports
Cell Reports, 28(12), 3105
Cell Reports, 28(12), 3105-3119.e7. Cell Press
Abels, E R, Maas, S L N, Nieland, L, Wei, Z, Cheah, P S, Tai, E, Kolsteeg, C-J, Dusoswa, S A, Ting, D T, Hickman, S, el Khoury, J, Krichevsky, A M, Broekman, M L D & Breakefield, X O 2019, ' Glioblastoma-Associated Microglia Reprogramming Is Mediated by Functional Transfer of Extracellular miR-21 ', Cell Reports, vol. 28, no. 12, pp. 3105-3119.e7 . https://doi.org/10.1016/j.celrep.2019.08.036
Cell Reports, 28(12), 3105. Cell Press
Cell Reports, Vol 28, Iss 12, Pp 3105-3119.e7 (2019)
Cell Reports, 28(12), 3105
Cell Reports, 28(12), 3105-3119.e7. Cell Press
Abels, E R, Maas, S L N, Nieland, L, Wei, Z, Cheah, P S, Tai, E, Kolsteeg, C-J, Dusoswa, S A, Ting, D T, Hickman, S, el Khoury, J, Krichevsky, A M, Broekman, M L D & Breakefield, X O 2019, ' Glioblastoma-Associated Microglia Reprogramming Is Mediated by Functional Transfer of Extracellular miR-21 ', Cell Reports, vol. 28, no. 12, pp. 3105-3119.e7 . https://doi.org/10.1016/j.celrep.2019.08.036
Cell Reports, 28(12), 3105. Cell Press
Cell Reports, Vol 28, Iss 12, Pp 3105-3119.e7 (2019)
SUMMARY Gliomas are primary, diffusely infiltrating brain tumors. Microglia are innate immune cells in the CNS and make up a substantial portion of the tumor mass. Glioma cells shape their microenvironment, communicating with and reprogramming surrou