Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Lisa Meisel"'
Autor:
Colúm Connolly, Clemens Steegborn, Donald C. Lo, Albena T. Dinkova-Kostova, Andrew Snyder, Vanita Chopra, Alexei Degterev, Michael A. Schwarzschild, Cho Low, Ulrike Träger, Leslie M. Thompson, Michael J. Van Kanegan, James R. Miller, Matthew Fuszard, Ningzhe Zhang, Ellen Sapp, Susanta Samajdar, Lisa Meisel, Kimberly B. Kegel-Gleason, Petr Vodicka, Adelaide Tousley, Lisa M. Ellerby, David Llères, Sébastien Moniot, Aleksey G. Kazantsev, Steven M. Hersch, Lisa A. Crawford, Ross S. Stein, Sarah J. Tabrizi, Eranthie Weerapana, Vijay Potluri, Linda S. Kaltenbach, Ruth Farmer, Blair R. Leavitt, Maureen Higgins, Luisa Quinti, Marian DiFiglia, Sharadha Dayalan Naidu, Xiqun Chen
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, vol 114, iss 23
The activity of the transcription factor nuclear factor-erythroid 2 p45-derived factor 2 (NRF2) is orchestrated and amplified through enhanced transcription of antioxidant and antiinflammatory target genes. The present study has characterized a triaz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bba6be10075b3b40875d35cd1e72bd7
https://researchonline.lshtm.ac.uk/id/eprint/3931063/1/KEAP1.pdf
https://researchonline.lshtm.ac.uk/id/eprint/3931063/1/KEAP1.pdf
Autor:
John Landers, J. Lawrence Marsh, Donald C. Lo, Teresa F. Pais, Eddine Saiah, Sébastien Moniot, Linda S. Kaltenbach, Aleksey G. Kazantsev, Clemens Steegborn, Michelle M. Maxwell, Sharadha Dayalan Naidu, Lisa Meisel, Albena T. Dinkova-Kostova, Leslie M. Thompson, Heike Runne, Michael J. Van Kanegan, Ryan G. Lim, Malcolm Casale, Judit Pallos, Nazifa Abdul Rauf, Ruben Abagyan, Luisa Quinti, Ruth Luthi-Carter, Dmitriy Leyfer
Publikováno v:
Cell chemical biology, vol 23, iss 7
Quinti, L; Casale, M; Moniot, S; Pais, TF; Van Kanegan, MJ; Kaltenbach, LS; et al.(2016). SIRT2-and NRF2-Targeting Thiazole-Containing Compound with Therapeutic Activity in Huntington's Disease Models. CELL CHEMICAL BIOLOGY, 23(7), 849-861. doi: 10.1016/j.chembiol.2016.05.015. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/3bp0f2h0
Quinti, L; Casale, M; Moniot, S; Pais, TF; Van Kanegan, MJ; Kaltenbach, LS; et al.(2016). SIRT2-and NRF2-Targeting Thiazole-Containing Compound with Therapeutic Activity in Huntington's Disease Models. CELL CHEMICAL BIOLOGY, 23(7), 849-861. doi: 10.1016/j.chembiol.2016.05.015. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/3bp0f2h0
There are currently no disease-modifying therapies for the neurodegenerative disorder Huntington's disease (HD). This study identified novel thiazole-containing inhibitors of the deacetylase sirtuin-2 (SIRT2) with neuroprotective activity in exvivo b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f06b599a60590742964de076360eeb8
https://infoscience.epfl.ch/record/222350
https://infoscience.epfl.ch/record/222350