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Akademický článek

Optimizing methods and dodging pitfalls in microbiome research

Autor: Dorothy Kim, Casey E. Hofstaedter, Chunyu Zhao, Lisa Mattei, Ceylan Tanes, Erik Clarke, Abigail Lauder, Scott Sherrill-Mix, Christel Chehoud, Judith Kelsen, Máire Conrad, Ronald G. Collman, Robert Baldassano, Frederic D. Bushman, Kyle Bittinger

Publikováno v: Microbiome, Vol 5, Iss 1, Pp 1-14 (2017)

Abstract Research on the human microbiome has yielded numerous insights into health and disease, but also has resulted in a wealth of experimental artifacts. Here, we present suggestions for optimizing experimental design and avoiding known pitfalls,

Externí odkaz: https://doaj.org/article/b4734cebc798435bbb26b8cc6d6c1d5a

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Gut microbiota changes are detected in asymptomatic very young children with SARS-CoV-2 infection

Autor: Lydia Nashed, Jyoti Mani, Sahel Hazrati, David B Stern, Poorani Subramanian, Lisa Mattei, Kyle Bittinger, Weiming Hu, Shira Levy, George L Maxwell, Suchitra K Hourigan

Publikováno v: Gut

Objective Although COVID-19 is primarily a respiratory illness, there is mounting evidence suggesting that the GI tract is involved in this disease. We investigated whether the gut microbiome is linked to disease severity in patients with COVID-19, a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::462106e424dd390bd7e06d01ea716ead
https://pubmed.ncbi.nlm.nih.gov/33431578

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The impact of environmental pH on the gut microbiota community structure and short chain fatty acid production

Autor: Jenni Firrman, LinShu Liu, Karley Mahalak, Ceylan Tanes, Kyle Bittinger, Vincent Tu, Jamshed Bobokalonov, Lisa Mattei, Huanjia Zhang, Pieter Van den Abbeele

Publikováno v: FEMS microbiology ecology. 98(5)

Environmental pH is a critical parameter for maintenance of the gut microbiota. Here, the impact of pH on the gut microbiota luminal and mucosal community structure and short chain fatty acid (SCFA) production was evaluated in vitro, and data compile

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::114d46f5efaa7ff49cd0a0d52b6c59e1
https://pubmed.ncbi.nlm.nih.gov/35383853

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482. SARS-CoV-2 Prevalence in Feces of Very Young Children, A Longitudinal Study

Autor: Lydia M Nashed, Jyoti Mani, Sahel Hazrati, Tiana Richards, Naya Nerikar, Shreeya Ravi, Lisa Mattei, Shira Levy, George Maxwell, Suchitra Hourigan

Publikováno v: Open Forum Infectious Diseases

Background Understanding the disease burden of SARS- CoV-2 in young children has been challenging as the majority are asymptomatic or experience mild symptoms and were rarely tested. SARS-CoV-2 is traditionally detected through respiratory secretions

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca32cbd7da21718cf106e25a75d7cff2
http://europepmc.org/articles/PMC8644872

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