Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Lisa Marx-Blümel"'
Autor:
Christian Marx, Jürgen Sonnemann, Oliver D. K. Maddocks, Lisa Marx-Blümel, Mandy Beyer, Doerte Hoelzer, René Thierbach, Claudia Maletzki, Michael Linnebacher, Thorsten Heinzel, Oliver H. Krämer
Publikováno v:
Cancer & Metabolism, Vol 10, Iss 1, Pp 1-17 (2022)
Abstract Background Metabolic adaptations can allow cancer cells to survive DNA-damaging chemotherapy. This unmet clinical challenge is a potential vulnerability of cancer. Accordingly, there is an intense search for mechanisms that modulate cell met
Externí odkaz:
https://doaj.org/article/b54be1c1c57b4247a2dde92cec4134b4
Autor:
Alena Gschwind, Christian Marx, Marie D. Just, Paula Severin, Hannah Behring, Lisa Marx-Blümel, Sabine Becker, Linda Rothenburger, Martin Förster, James F. Beck, Jürgen Sonnemann
Publikováno v:
Cellular & Molecular Biology Letters, Vol 27, Iss 1, Pp 1-20 (2022)
Abstract Background Autophagy plays an essential role in maintaining cellular homeostasis and in the response to cellular stress. Autophagy is also involved in cell cycle progression, yet the relationship between these processes is not clearly define
Externí odkaz:
https://doaj.org/article/80c924d65a344261b247c7fdff57d0f2
Autor:
Christian Marx, Jürgen Sonnemann, Mandy Beyer, Oliver D. K. Maddocks, Sergio Lilla, Irene Hauzenberger, Andrea Piée‐Staffa, Kanstantsin Siniuk, Suneetha Nunna, Lisa Marx‐Blümel, Martin Westermann, Tobias Wagner, Felix B. Meyer, René Thierbach, Christina S. Mullins, Said Kdimati, Michael Linnebacher, Francesco Neri, Thorsten Heinzel, Zhao‐Qi Wang, Oliver H. Krämer
Publikováno v:
Molecular Oncology, Vol 15, Iss 12, Pp 3404-3429 (2021)
Late‐stage colorectal cancer (CRC) is still a clinically challenging problem. The activity of the tumor suppressor p53 is regulated via post‐translational modifications (PTMs). While the relevance of p53 C‐terminal acetylation for transcription
Externí odkaz:
https://doaj.org/article/0b74c48fb69942fab1d217753fe500f2
Autor:
Lisa Marx-Blümel, Christian Marx, Jürgen Sonnemann, Frank Weise, Jörg Hampl, Jessica Frey, Linda Rothenburger, Emilio Cirri, Norman Rahnis, Philipp Koch, Marco Groth, Andreas Schober, Zhao-Qi Wang, James F. Beck
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Hematopoietic stem cell (HSC) transplantation is successfully applied since the late 1950s. However, its efficacy can be impaired by insufficient numbers of donor HSCs. A promising strategy to overcome this hurdle is the use of an advanced e
Externí odkaz:
https://doaj.org/article/c3458d44a6a74132a128e0b81a5e3c4c
Autor:
Christian Marx, Marc U. Schaarschmidt, Joanna Kirkpatrick, Lisa Marx-Blümel, Melisa Halilovic, Martin Westermann, Doerte Hoelzer, Felix B. Meyer, Yibo Geng, Katrin Buder, Hauke M. Schadwinkel, Kanstantsin Siniuk, Sabine Becker, René Thierbach, James F. Beck, Jürgen Sonnemann, Zhao-Qi Wang
Publikováno v:
Cell & Bioscience, Vol 11, Iss 1, Pp 1-19 (2021)
Abstract Introduction Ewing's sarcoma is an aggressive childhood malignancy whose outcome has not substantially improved over the last two decades. In this study, combination treatments of the HSP90 inhibitor AUY922 with either the ATR inhibitor VE82
Externí odkaz:
https://doaj.org/article/d8fb96d8e11f4e79b641bb5a2f9a1a6f
Autor:
Anne Hahn, Daniel Pensold, Cathrin Bayer, Jessica Tittelmeier, Lourdes González-Bermúdez, Lisa Marx-Blümel, Jenice Linde, Jonas Groß, Gabriela Salinas-Riester, Thomas Lingner, Julia von Maltzahn, Marc Spehr, Tomas Pieler, Anja Urbach, Geraldine Zimmer-Bensch
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Increased life expectancy in modern society comes at the cost of age-associated disabilities and diseases. Aged brains not only show reduced excitability and plasticity, but also a decline in inhibition. Age-associated defects in inhibitory circuits
Externí odkaz:
https://doaj.org/article/0f47d2d2087640479b08d94451253150
Publikováno v:
BIOspektrum. 28:489-492
A promising strategy to increase the numbers of hematopoietic stem cells (HSCs) for clinical applications, like stem cell transplantation, is offered by advanced in vitro culture systems. We developed artificial 3D bone marrow-like scaffolds made of
Autor:
Melisa Halilovic, Lisa Marx-Blümel, Christian Marx, Katrin Buder, James F. Beck, Jürgen Sonnemann
Publikováno v:
Methods in Molecular Biology ISBN: 9781071627877
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::56b4215d355700dafb1a85a28fae1f02
https://doi.org/10.1007/978-1-0716-2788-4_17
https://doi.org/10.1007/978-1-0716-2788-4_17
Publikováno v:
Methods in Molecular Biology ISBN: 9781071627877
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ed68723ba820d64598fa74c54101b5f0
https://doi.org/10.1007/978-1-0716-2788-4_18
https://doi.org/10.1007/978-1-0716-2788-4_18
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2589
Posttranslational modifications are important for protein functions and cellular signaling pathways. The acetylation of lysine residues is catalyzed by histone acetyltransferases (HATs) and removed by histone deacetylases (HDACs), with the latter bei