Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Lisa Marie Serrano"'
Autor:
Laurence J.N. Cooper, Andrew Raubitschek, David Colcher, Michael C. Jensen, Stephen D. Gillies, Stephen J. Forman, Zaid Al-Kadhimi, David D. Smith, George McNamara, Simon Olivares, Timothy Pfeiffer, Lisa Marie Serrano, Harjeet Singh
Supplementary Video 2 from Combining Adoptive Cellular and Immunocytokine Therapies to Improve Treatment of B-Lineage Malignancy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fc4db6ac313743aff937b78034399e3
https://doi.org/10.1158/0008-5472.22366020.v1
https://doi.org/10.1158/0008-5472.22366020.v1
Autor:
Laurence J.N. Cooper, Andrew Raubitschek, David Colcher, Michael C. Jensen, Stephen D. Gillies, Stephen J. Forman, Zaid Al-Kadhimi, David D. Smith, George McNamara, Simon Olivares, Timothy Pfeiffer, Lisa Marie Serrano, Harjeet Singh
Supplementary Video 1 from Combining Adoptive Cellular and Immunocytokine Therapies to Improve Treatment of B-Lineage Malignancy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b9ac6d850670d4df1a5930b88ccee86
https://doi.org/10.1158/0008-5472.22366023
https://doi.org/10.1158/0008-5472.22366023
Autor:
Laurence J.N. Cooper, Andrew Raubitschek, David Colcher, Michael C. Jensen, Stephen D. Gillies, Stephen J. Forman, Zaid Al-Kadhimi, David D. Smith, George McNamara, Simon Olivares, Timothy Pfeiffer, Lisa Marie Serrano, Harjeet Singh
Currently, the lineage-specific cell-surface molecules CD19 and CD20 present on many B-cell malignancies are targets for both antibody- and cell-based therapies. Coupling these two treatment modalities is predicted to improve the antitumor effect, pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78aa1093a4b5a0e4ecb299341a9257b0
https://doi.org/10.1158/0008-5472.c.6494955.v1
https://doi.org/10.1158/0008-5472.c.6494955.v1
Autor:
Zaid S Al-Kadhimi, David Colcher, Timothy Pfeiffer, Stephen J. Forman, Lisa Marie Serrano, Simon Olivares, Michael C. Jensen, Stephen D. Gillies, Harjeet Singh, David D. Smith, George McNamara, Andrew Raubitschek, Laurence J.N. Cooper
Publikováno v:
Cancer Research. 67:2872-2880
Currently, the lineage-specific cell-surface molecules CD19 and CD20 present on many B-cell malignancies are targets for both antibody- and cell-based therapies. Coupling these two treatment modalities is predicted to improve the antitumor effect, pa
Autor:
Timothy Pfeiffer, Sergio Gonzalez, Simon Olivares, Michael C. Jensen, Wen-Chung Chang, Stephen J. Forman, David D. Smith, Adrian Castro, Lisa Marie Serrano, Zaid S Al-Kadhimi, Laurence J.N. Cooper
Publikováno v:
Blood. 105:1622-1631
To enhance the in vivo antitumor activity of adoptively transferred, CD19-specific chimeric antigen receptor (CAR)–redirected cytotoxic T lymphocytes (CTLs), we studied the effect of restimulating CAR+ CTLs through their endogenous virus-specific T
Autor:
Christine L. Wright, Wen-Chung Chang, Lisa Marie Serrano, Sergio Gonzalez, Araceli Naranjo, Michael C. Jensen
Publikováno v:
The Journal of Gene Medicine. 6:704-711
Background Disease relapse is the leading cause of mortality for children diagnosed with disseminated neuroblastoma. The adoptive transfer of tumor-specific T cells is an attractive approach to target minimal residual disease following conventional t
Autor:
Leslie Popplewell, Christine L. Wright, Wen-Chung Chang, Sergio Gonzalez, Andrew Raubitschek, Max S. Topp, Araceli Naranjo, Lisa Marie Serrano, Michael C. Jensen, Laurence J.N. Cooper, Stephen J. Forman
Publikováno v:
Blood. 101:1637-1644
Relapse of B-lineage acute lymphoblastic leukemia (B-ALL) after allogeneic hematopoietic stem cell transplantation (HSCT) commonly results from the failure of a graft-versus-leukemia (GVL) effect to eradicate minimal residual disease. Augmenting the
Autor:
S.J. Forman, Laurence J.N. Cooper, Lisa Marie Serrano, Wen-Chung Chang, N. González, Claudia M. Kowolik, Simon Olivares, Michael C. Jensen, Harjeet Singh, Tontanai Numbenjapon
Publikováno v:
Leukemia. 20(10)
Characterization of an artificial antigen-presenting cell to propagate cytolytic CD19-specific T cells
Autor:
Wen-Chung Chang, Michael C. Jensen, Stephen J. Forman, Tontanai Numbenjapon, Lisa Marie Serrano, Laurence J.N. Cooper
Publikováno v:
Experimental hematology. 35(7)
Objective Preclinical and clinical trials are investigating the potential of T cells genetically modified to express a first-generation CD19-specific chimeric antigen receptor (CAR), designated CD19R, for adoptive immunotherapy of B-lineage leukemias
Autor:
L. Burton, M. Gutierrez, S.J. Forman, R. Shakeley, Laurence J.N. Cooper, David DiGiusto, Lisa Marie Serrano, L. Ausubel, S. Stephan, Simon Olivares, Michael C. Jensen
Publikováno v:
Cytotherapy. 8(2)
The production of therapeutic T-cell populations for adoptive immunotherapy of cancer requires extensive ex vivo cell processing, including the isolation or creation of Ag-specific T cells and their subsequent propagation to clinically relevant numbe