Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Lisa Maria Mustachio"'
Autor:
Zibo Chen, Lin Zheng, Yulong Chen, Xiuxia Liu, Masanori Kawakami, Lisa Maria Mustachio, Jason Roszik, Katherine V. Ferry-Galow, Ralph E. Parchment, Xin Liu, Thorkell Andresson, Gerard Duncan, Jonathan M. Kurie, Jaime Rodriguez-Canales, Xi Liu, Ethan Dmitrovsky
Publikováno v:
Cancer Biology & Therapy, Vol 23, Iss 1, Pp 265-280 (2022)
Cancer metastasis is a major cause of cancer-related mortality. Strategies to reduce metastases are needed especially in lung cancer, the most common cause of cancer mortality. We previously reported increased ubiquitin-specific peptidase 18 (USP18)
Externí odkaz:
https://doaj.org/article/89c6b8309f354ba2877fae72139376be
Autor:
Ethan Dmitrovsky, Sarah J. Freemantle, Duane A. Compton, Faye M. Johnson, Masanori Kawakami, Xi Liu, David Sekula, Lisa Maria Mustachio, Kristina Godek, Bernardo Orr, Shanhu Hu, Alexey V. Danilov
Despite advances in targeted therapy, lung cancer remains the most common cause of cancer-related mortality in the United States. Chromosomal instability is a prominent feature in lung cancer and, because it rarely occurs in normal cells, it represen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74fbb1680fe603f0fbb03a3c416c60d0
https://doi.org/10.1158/1535-7163.c.6538363
https://doi.org/10.1158/1535-7163.c.6538363
Autor:
Ethan Dmitrovsky, Sarah J. Freemantle, Xi Liu, Shanhu Hu, Fadzai Chinyengetere, John F. Hancock, Kwang-jin Cho, Masanori Kawakami, Jason Roszik, Samir M. Hanash, Hiroyuki Katayama, Ignacio Wistuba, Pamela Andrea Villalobos, Barbara Mino, Jaime Rodriguez-Canales, Vincent Memoli, Laura J. Tafe, Yun Lu, Lisa Maria Mustachio
KRAS is frequently mutated in lung cancers and is associated with aggressive biology and chemotherapy resistance. Therefore, innovative approaches are needed to treat these lung cancers. Prior work implicated the IFN-stimulated gene 15 (ISG15) deubiq
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fd5c9584958b0a004b044ec7e99060a1
https://doi.org/10.1158/1541-7786.c.6539967.v1
https://doi.org/10.1158/1541-7786.c.6539967.v1
Autor:
Ethan Dmitrovsky, Sarah Freemantle, Duane A. Compton, David Sekula, Masanori Kawakami, Lisa Maria Mustachio, Kristina Godek, Bernardo Orr, Yun Lu, Shanhu Hu
Knock-down of Usp33 in murine lung cancer cells does not affect CP110 protein expression. Effects of Usp33 knock-down at 24,48, 72 and 96 hours on CP110 expression in ED-1 cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3df3c9b4dab96bc8e6fe93915d34e495
https://doi.org/10.1158/1535-7163.22505949
https://doi.org/10.1158/1535-7163.22505949
Autor:
Ethan Dmitrovsky, Sarah J. Freemantle, Duane A. Compton, Faye M. Johnson, Masanori Kawakami, Xi Liu, David Sekula, Lisa Maria Mustachio, Kristina Godek, Bernardo Orr, Shanhu Hu, Alexey V. Danilov
Movie video files of a) H1299 and b) HOP62 cells were treated with 25 or 50 nM dinaciclib and continuously imaged as described in the Methods.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9069a8a0528305d25c2d498b03683e42
https://doi.org/10.1158/1535-7163.22506325.v1
https://doi.org/10.1158/1535-7163.22506325.v1
Autor:
Ethan Dmitrovsky, Xi Liu, Tak W. Mak, Ignacio I. Wistuba, Jaime Rodriguez-Canales, David W Cescon, Kelsie L. Thu, Jennifer Silvester, Luisa M. Solis, Barbara Mino, Carmen Behrens, Wei Lu, Pamela Villalobos, Jonathan M. Kurie, Lisa Maria Mustachio, Jason Roszik, Yulong Chen, Masanori Kawakami, Zibo Chen, Lin Zheng
The spindle assembly checkpoint maintains genomic integrity. A key component is tyrosine threonine kinase (TTK, also known as Mps1). TTK antagonism is hypothesized to cause genomic instability and cell death. Interrogating The Cancer Genome Atlas rev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2aa57f94649535dc1900eeb0fa9c6cbf
https://doi.org/10.1158/1535-7163.c.6537774.v1
https://doi.org/10.1158/1535-7163.c.6537774.v1
Autor:
Ethan Dmitrovsky, Sarah Freemantle, Duane A. Compton, David Sekula, Masanori Kawakami, Lisa Maria Mustachio, Kristina Godek, Bernardo Orr, Yun Lu, Shanhu Hu
The siRNA sequences used in this study.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21f3ad6395ab4607ef514ac579c22f1f
https://doi.org/10.1158/1535-7163.22505943
https://doi.org/10.1158/1535-7163.22505943
Autor:
Ethan Dmitrovsky, Sarah J. Freemantle, Masanori Kawakami, Jason Roszik, Stephen Fox, Thorkell Adresson, Lisa Maria Mustachio, Mi Shi, Jonathan M. Kurie, Yulong Chen, Lin Zheng, Weiguo Hu, Xiuxia Liu, Zibo Chen, Yun Lu, Xi Liu
Ubiquitin specific peptidase 18 (USP18), previously known as UBP43, is the IFN-stimulated gene 15 (ISG15) deconjugase. USP18 removes ISG15 from substrate proteins. This study reports that USP18-null mice (vs. wild-type mice) exhibited lower lipolysis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::29a0252a3d461eff34d0b0fc062e38e8
https://doi.org/10.1158/1541-7786.c.6545009.v1
https://doi.org/10.1158/1541-7786.c.6545009.v1
Autor:
Ethan Dmitrovsky, Xi Liu, Tak W. Mak, Ignacio I. Wistuba, Jaime Rodriguez-Canales, David W Cescon, Kelsie L. Thu, Jennifer Silvester, Luisa M. Solis, Barbara Mino, Carmen Behrens, Wei Lu, Pamela Villalobos, Jonathan M. Kurie, Lisa Maria Mustachio, Jason Roszik, Yulong Chen, Masanori Kawakami, Zibo Chen, Lin Zheng
Figure S1: The structure of CFI-402257. Figure S2: TTK mRNA expression profiles in lung cancer cases with different smoking patterns, as shown in panel A. In this left panel N means no smoking history while Y indicates the presence of a smoking histo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8022f80f2f05d71c7880d9bd62d6aa72
https://doi.org/10.1158/1535-7163.22504551.v1
https://doi.org/10.1158/1535-7163.22504551.v1
Autor:
Ethan Dmitrovsky, Xi Liu, Jonathan M. Kurie, Sarah J. Freemantle, Liliya Tyutyunyk-Massey, John V. Heymach, Jing Wang, Bingliang Fang, Xiaoshan Zhang, Alexey V. Danilov, Adam S. Kittai, Jason Roszik, Cheng-Hsin Wei, Xiuxia Liu, Zibo Chen, Yulong Chen, Lisa Maria Mustachio, Masanori Kawakami
Supplementary table
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::055abda53a037af0d7e0346b42ab4b5c
https://doi.org/10.1158/1535-7163.22521741
https://doi.org/10.1158/1535-7163.22521741