Infection-induced membrane ruffling initiates danger and immune signaling via the mechanosensor PIEZO1

Autor: Lalitha Tadala, Dorothee Langenbach, Mirjam Dannborg, Ramón Cervantes-Rivera, Atin Sharma, Kevin Vieth, Lisa M. Rieckmann, Alkwin Wanders, David A. Cisneros, Andrea Puhar

Publikováno v: Tadala, L, Langenbach, D, Dannborg, M, Cervantes-Rivera, R, Sharma, A, Vieth, K, Rieckmann, L M, Wanders, A, Cisneros, D A & Puhar, A 2022, ' Infection-induced membrane ruffling initiates danger and immune signaling via the mechanosensor PIEZO1 ', Cell reports, vol. 40, no. 6, 111173 . https://doi.org/10.1016/j.celrep.2022.111173

Microorganisms are generally sensed by receptors recognizing microbial molecules, which evoke changes in cellular activities and gene expression. Bacterial pathogens induce secretion of the danger signal ATP as an early alert response of intestinal e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21063073e9afcd4012ef97ab2bb94154
https://pubmed.ncbi.nlm.nih.gov/35947957

Virulence Factors Produced by

Autor: Alexander C, Graf, Anne, Leonard, Manuel, Schäuble, Lisa M, Rieckmann, Juliane, Hoyer, Sandra, Maass, Michael, Lalk, Dörte, Becher, Jan, Pané-Farré, Katharina, Riedel

Publikováno v: Mol Cell Proteomics

Staphylococcus aureus is the causative agent of various biofilm-associated infections in humans causing major healthcare problems worldwide. This type of infection is inherently difficult to treat because of a reduced metabolic activity of biofilm-em

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::70e5de6693014b32cff5e9ef54bbde6a
https://pubmed.ncbi.nlm.nih.gov/30850421