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pro vyhledávání: '"Lisa M. Pleasants"'
Genetic polymorphism at the glutathione S‐tranferase (GST) P1 locus is a breast cancer risk modifier
Autor:
Christine M. Maugard, Francis Ali-Osman, Loïc Campion, Lisa M. Pleasants, Olanike Akande, Josiane Charrier, Armelle Pitard
Publikováno v:
International Journal of Cancer. 91:334-339
The isolation of full-length cDNAs of naturally occurring GSTP1 gene variants, and the demonstration that these alleles are distributed in the normal population, have provided conclusive evidence that the human GSTP1 gene locus is polymorphic and tha
Autor:
Peter W. Jones, John T. Lear, Anthony A. Fryer, Richard C. Strange, Paul R. Hoban, Francis Ali-Osman, Fumiyo Ichii-Jones, Lisa M. Pleasants, Sudarshan Ramachandran, Andrew G. Smith, Bill Bowers
Publikováno v:
Pharmacogenetics. 10:545-556
We previously described associations between basal cell carcinoma (BCC) numbers and allelic variants at loci that mediate host response to ultraviolet radiation (UV). These associations were largely exerted in cases with the multiple presentation phe
Autor:
Marc F. Hansen, Lisa M. Pleasants
Publikováno v:
Human genetics. 93(5)
A polymorphism in intron 2 of the p53 gene was identified by single-strand conformation polymorphism analysis. The result is a G-to-C transversion at bp +38 following the splice donor site of exon 2.
Autor:
Marc F. Hansen, Laura L. Whitaker, Farideh Z. Bischoff, Elizabeth L. Schubert, Lisa M. Pleasants
Publikováno v:
Human mutation. 2(2)
The tumor suppressor gene p53 is involved in predisposition to a variety of human cancers, including those from Li-Fraumeni cancer family syndrome patients. Studies of inheritance of p53 germline mutations require confirmation of the mutation in the