Zobrazeno 1 - 10
of 95
pro vyhledávání: '"Lisa M. Kaminskas"'
Autor:
Margaret Murray, Christopher K. Barlow, Scott Blundell, Mark Buecking, Anne Gibbon, Bernd Goeckener, Lisa M. Kaminskas, Patricia Leitner, Sophie Selby-Pham, Andrew Sinclair, Habtewold D. Waktola, Gary Williamson, Louise E. Bennett
Publikováno v:
Frontiers in Nutrition, Vol 10 (2023)
BackgroundThere is a need to better understand the relationship between the diet, the gut microbiota and mental health. Metabolites produced when the human gut microbiota metabolize amino acids may enter the bloodstream and have systemic effects. We
Externí odkaz:
https://doaj.org/article/5be3500fe4f942188ada8127476c974f
Autor:
Nirmal Marasini, Changkui Fu, Nicholas L. Fletcher, Christopher Subasic, Gerald Er, Karine Mardon, Kristofer J. Thurecht, Andrew K. Whittaker, Lisa M. Kaminskas
Publikováno v:
Nanomaterials, Vol 10, Iss 12, p 2452 (2020)
A better understanding of the impact of molecular size and linkers is important for PEG-based hyperbranched polymers (HBPs) intended as tailored drug delivery vehicles. This study aimed to evaluate the effects of crosslinker chemistry (cleavable disu
Externí odkaz:
https://doaj.org/article/bcce3ebefc034a4aafa263e7f81bc261
Publikováno v:
Molecular Pharmaceutics.
Autor:
Nirmal Marasini, Gerald Er, Changkui Fu, Christopher N. Subasic, Jibriil Ibrahim, Mariusz Skwarczynski, Istvan Toth, Andrew K. Whittaker, Lisa M. Kaminskas
Publikováno v:
Acta Biomaterialia. 142:298-307
Methotrexate (MTX) is an effective disease modifying anti-rheumatic drug, but can cause significant hepatotoxicity and liver failure in some individuals. The goal of this work was to develop a MTX-conjugated hyperbranched polymeric nanoparticle based
Publikováno v:
Journal of Controlled Release. 337:71-80
PEGylated liposomal doxorubicin (PLD, Caelyx®, Doxil®) has been suggested to show significant sex-based differences in plasma clearance, as well as high inter-individual variability that may be driven by monocyte counts in cancer patients. This stu
Publikováno v:
Computer-Aided Antibody Design ISBN: 9781071626085
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a228412905a555a788512e1ee5da68c0
https://doi.org/10.1007/978-1-0716-2609-2_21
https://doi.org/10.1007/978-1-0716-2609-2_21
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2552
Antibodies are essential experimental and diagnostic tools and as biotherapeutics have significantly advanced our ability to treat a range of diseases. With recent innovations in computational tools to guide protein engineering, we can now rationally
Publikováno v:
Journal of Pharmaceutical Investigation
Background Vaccines are often recognized as one of the most cost-effective public health interventions in controlling infectious diseases. Most pathogens infiltrate the body from mucosal sites, primarily from the oral and pulmonary region and reach t
Autor:
Jibriil P Ibrahim, Shadabul Haque, Robert J Bischof, Andrew K Whittaker, Michael R Whittaker, Lisa M Kaminskas
Publikováno v:
Frontiers in Pharmacology. 13
Enhancing the delivery of therapeutic agents to the lung lymph, including drugs, transfection agents, vaccine antigens and vectors, has the potential to significantly improve the treatment and prevention of a range of lung-related illnesses. One way
Autor:
Cameron J. Nowell, Daniel H.S. Brundel, Lisa M. Kaminskas, Gracia Gracia, Orlagh M. Feeney, Christopher J.H. Porter, Michelle M. McIntosh, David W. Kang, Estelle J.A. Suys
Publikováno v:
Nanomedicine. 16:275-292
Aim: Delivery of nanoparticles (NPs) to tumors can be impeded by high levels of hyaluronan (HA) in the stroma. Enzymatic depolymerization of HA with PEGylated hyaluronidase (PEGPH20) improves the delivery of antibodies to tumors. However, it is unkno