Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Lisa M. Gazdzinski"'
Publikováno v:
BMC Neuroscience, Vol 23, Iss 1, Pp 1-8 (2022)
Abstract Background Following one mild traumatic brain injury (mTBI), there is a window of vulnerability during which subsequent mTBIs can cause substantially exacerbated impairments. Currently, there are no known methods to monitor, shorten or mitig
Externí odkaz:
https://doaj.org/article/0220d94bfd8b41e1837fd04dabb981de
Autor:
Sun Eui Choi, Anum Rahman, Tiffany Ayoub, Owen Botelho, Gail Lee, Lisa M. Gazdzinski, Anne L. Wheeler, Rosanna Weksberg, Sharon L. Guger, Russell J. Schachar, Shinya Ito, Johann Hitzler, Brian J. Nieman
Publikováno v:
Journal of neuroscience methods. 386
Intrathecal injections provide important access to the central nervous system for delivery of anesthetic, analgesic or chemotherapeutic drugs that do not otherwise cross the blood-brain barrier. The administration of drugs via this route in animal mo
Autor:
Seyed Amir Ali Adel, Tong Wang, Miranda Mellerup, Anne L. Wheeler, Jason P. Lerch, Lisa M. Gazdzinski, Brian J. Nieman, John G. Sled
Publikováno v:
Journal of neurotrauma. 37(16)
Mild traumatic brain injury (mTBI) is common and can lead to persistent cognitive and behavioral symptoms. Although diffusion tensor imaging (DTI) has demonstrated some sensitivity to changes in white matter following mTBI, recent studies have sugges
Autor:
John G. Sled, Lisa M. Gazdzinski, Adrienne Dorr, Jonathan Bishop, Bojana Stefanovic, Lindsay S. Cahill
Publikováno v:
Brain Structure and Function. 222:3395-3405
The beneficial effects of physical exercise on brain health are well documented, yet how exercise modulates cerebrovascular function is not well understood. This study used continuous arterial spin labeling magnetic resonance imaging with a hypercapn
Autor:
John G. Sled, Elaine Liu, Lisa M. Gazdzinski, Lindsay S. Cahill, Sharon Portnoy, Yu-Qing Zhou, C. David Mazer, Gregory M. T. Hare, Albert K. Y. Tsui, Andrea Kassner
Publikováno v:
Journal of Cerebral Blood Flow & Metabolism. 37:994-1005
Cerebral ischemia is a significant source of morbidity in children with sickle cell anemia; however, the mechanism of injury is poorly understood. Increased cerebral blood flow and low hemoglobin levels in children with sickle cell anemia are associa
Autor:
John G. Sled, Lisa M. Gazdzinski, Linda Kalilani-Phiri, Kevin C. Kain, Lindsay S. Cahill, Victor Mwapasa, Robyn E. Elphinstone, Mwayiwawo Madanitsa, Kathleen Zhong, Joel L. Gamble, Adrienne C. Philson, Andrea L. Conroy, Feiko O. ter Kuile, Chloe R. McDonald
Publikováno v:
Science Translational Medicine
Reducing adverse birth outcomes due to malaria in pregnancy (MIP) is a global health priority. However, there are few safe and effective interventions. L-arginine is an essential amino acid in pregnancy and an immediate precursor in the biosynthesis
Autor:
Jon Pipitone, Chris Fryer, Brian J. Nieman, Douglas Strother, A. Elizabeth de Guzman, Eric Bouffet, Lily Riggs, M. Mallar Chakravarty, Jovanka Skocic, Jason P. Lerch, Lisa M. Gazdzinski, Donald J. Mabbott, Suzanne Laughlin, Normand Laperriere
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 93(4):882-891
Purpose Pediatric patients treated with cranial radiation are at high risk of developing lasting cognitive impairments. We sought to identify anatomical changes in both gray matter (GM) and white matter (WM) in radiation-treated patients and in mice,
Autor:
Brian J. Nieman, Lisa M. Gazdzinski
Publikováno v:
Magnetic Resonance in Medicine. 71:1531-1541
Purpose The heterogeneous tumor cell population and dynamic microenvironment within a tumor lead to regional variations in cell proliferation, migration, and differentiation. In this work, MRI and optical projection tomography were used to examine an
Autor:
C. Shun Wong, A. Elizabeth de Guzman, Lisa M. Gazdzinski, David A. Jaffray, Richard J. Alsop, James Stewart, Brian J. Nieman
Publikováno v:
Radiation research. 183(5)
Pediatric cranial radiation therapy can induce long-term neurocognitive deficits, the risk and severity of these deficits are amplified in females and in those individuals exposed at a younger age and/or those irradiated at higher doses. To investiga
Autor:
Ahmed S. Said, Allan Doctor, Albert K. Y. Tsui, Lisa M. Gazdzinski, Gururaja Vulugundam, Santosh K. Misra, Greg Lanza, Nikhil Mistry, Greg Hare, Dipanjan Pan, Philip C. Spinella, Stephen C. Rogers
Publikováno v:
Blood. 128:1027-1027
BACKGROUND: There is need for an artificial oxygen (O2) carrier for use when: stored blood is unavailable or undesirable. To date, efforts to develop hemoglobin (Hb) based oxygen carriers (HBOCs) have failed, because of design flaws which do not pres