Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Lisa M. Churgay"'
Autor:
Melvyn Baez, Lisa M. Churgay, Mcclure Don B, Leonard N. Boggs, Patrick C. May, Kimberly S. Fuson, Gerald W. Becker
Publikováno v:
Journal of Neurochemistry. 67:1324-1327
Clusterin is a secreted glycoprotein that is markedly induced in many disease states and after tissue injury. In the CNS, clusterin expression is elevated in neuropathological conditions such as Alzheimer's disease (AD), where it is found associated
Autor:
Gerald W. Becker, John E. Hale, Laurane G. Mendelsohn, Rama M. Belagaje, Melvin G. Johnson, John M. Richardson, Lillian L. Habeck, Xiao-Yan Yang, Maverick Ulmer, Katherine A. Shackelford, Lisa M. Churgay
Publikováno v:
The Prostate. 46:298-306
BACKGROUND Prostate-specific antigen (PSA), a member of the kallikrein family of serine proteases, is a chymotrypsin-like glycoprotein produced by the prostate epithelium. Elevated serum PSA (> 4 ng/ml) is a tumor marker for prostatic cancer and beni
Autor:
Lisa M. Churgay, Gerald Gold, John J. Osborne, Gerald W. Becker, Genshi Zhao, John E. Hale, Stramm Lawrence E, Yuguang Shi, Jie An
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 277:E862-E869
Treatment of the pancreatic β-cell line βTC6-F7 with an imidazoline compound, RX-871024, KCl, or tolbutamide resulted in increased threonine phosphorylation of a 220-kDa protein (p220) concurrent with enhanced insulin secretion, which can be partia
Autor:
Gregory A. Cox, John E. Hale, Robert B. Johnson, Lisa M. Churgay, Q. May Wang, Elcira C. Villarreal
Publikováno v:
Journal of Virology. 72:1683-1687
Reported here is the production of recombinant human rhinovirus 14 (HRV14) 2A protease from bacterial cells transformed with a heat-inducible plasmid containing the HRV14 2A cDNA sequence. Overexpressed 2A protein partitioned into the inclusion bodie
Autor:
Brigitte Elisabeth Schoner, Richard D. DiMarchi, Stephen L. Briggs, Thomas Charles Furman, Lisa M. Churgay, Richard Walter Schevitz, John E. Hale, Dennis P. Smith, Jean-Pierre Wery, Xing Y. Zhang, David K. Clawson, Margret Barbara Basinski, Hansen M. Hsiung, Faming Zhang, John Michael Beals
Publikováno v:
Nature. 387:206-209
Mutations in the obese gene (OB) or in the gene encoding the OB receptor(OB-R) result in obesity, infertility and diabetes in a variety of mouse phenotypes. The demonstration that OB protein (also known as leptin) can normalize body weight in ob/ob m
Autor:
Steven Kovacevic, John E. Hale, Rohn L. Millican, Frank C. Tinsley, Cheryl M. Kussow, Lisa M. Churgay, James R. Miller
Publikováno v:
Gene. 190(1)
The product of the human ob (obesity) gene, leptin, appears to function in the maintenance of body weight in vivo. When injected into mice, this hormone reduces food consumption and causes weight loss. This work has been done with recombinant leptin
Publisher Summary Baculovirus infected insect cells represent an effective system for the overexpression of heterologous proteins. The level of soluble K-ras produced by these cells is quite high as seen in the chapter. Kirsten-ras is the most freque
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::da00c92e260087b4d2f94f38827379dc
https://doi.org/10.1016/s1080-8914(97)80081-6
https://doi.org/10.1016/s1080-8914(97)80081-6
Autor:
Debra K Martin, John M. Richardson, Gerald W. Becker, John E. Hale, Radhakrishnan Rathnachalam, Lisa M. Churgay, Muth William Lawrence, Maverick Ulmer, Allen D Kline, Bryan E. Landen, Brigitte Elisabeth Schoner
Publikováno v:
FEBS Letters. (2):239-242
Leptin is a signaling protein that in its mutant forms has been associated with obesity and Type II diabetes. The lack of sequence similarity has precluded analogies based on structural resemblance to known systems. Backbone NMR signals for mouse lep