Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Lisa M. Boulanger"'
Publikováno v:
Brain, Behavior, and Immunity. 56:197-208
Synapse elimination at the developing neuromuscular junction (NMJ) sculpts motor circuits, and synapse loss at the aging NMJ drives motor impairments that are a major cause of loss of independence in the elderly. Here we provide evidence that at the
Autor:
Adlai L. Pappy, Emily E. O’Driscoll, Lisa M. Boulanger, Jack W. Melson, Karla K. Frietze, David H. Perlman, Carolyn M. Tyler
Publikováno v:
BMC Immunology
Background Major histocompatibility complex class I (MHCI) proteins present antigenic peptides for immune surveillance and play critical roles in nervous system development and plasticity. Most MHCI are transmembrane proteins. The extracellular domai
Autor:
Carolyn M. Tyler, Christopher M. Davenport, Lisa M. Boulanger, Lawrence Fourgeaud, Timothy T. Cheng, Michael B. Spencer
Publikováno v:
Proceedings of the National Academy of Sciences. 107:22278-22283
Proteins of the major histocompatibility complex class I (MHCI) are known for their role in immunity and have recently been implicated in long-term plasticity of excitatory synaptic transmission. However, the mechanisms by which MHCI influences synap
Autor:
Lawrence Fourgeaud, Lisa M. Boulanger
Publikováno v:
European Journal of Neuroscience. 32:207-217
An increasing number of studies support an unexpected role for immune molecules in regulating healthy brain functions during development and in adulthood. Here we review the roles of specific immune molecules (including cytokines, components of the c
Autor:
Lisa M. Boulanger
Publikováno v:
Neuron. 64:93-109
Many proteins first identified in the immune system are also expressed in the developing and adult nervous system. Unexpectedly, recent studies reveal that a number of these proteins, in addition to their immunological roles, are essential for the es
The major histocompatibility complex class I (MHCI) is a large gene family, with over 30 members in mouse. Some MHCIs are well-known for their critical roles in the immune response. Studies in mice which lack stable cell-surface expression of many MH
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93c1638ebd83f077367fb6e984382d9b
https://europepmc.org/articles/PMC4821772/
https://europepmc.org/articles/PMC4821772/
Autor:
Matthew K. Belmonte, Andrea Beckel-Mitchener, Greg Allen, Ruth A. Carper, Lisa M. Boulanger, Sara Jane Webb
Publikováno v:
The Journal of Neuroscience. 24:9228-9231
It has been said that people with autism suffer from a lack of “central coherence,” the cognitive ability to bind together a jumble of separate features into a single, coherent object or concept ([Frith, 1989][1]). Ironically, the same can be sai
Autor:
Carla J. Shatz, Lisa M. Boulanger
Publikováno v:
Nature Reviews Neuroscience. 5:521-531
Research has long supported the view that the brain is immunologically privileged, in part because normal, uninfected neurons were not thought to express major histocompatibility complex (MHC) class I molecules. Recently, however, it has been shown t
Autor:
William T. Greenough, John L.R. Rubenstein, E K Perry, George M. Anderson, Edwin H. Cook, Matthew K. Belmonte, Andrea Beckel-Mitchener, Pat Levitt, Eric Courchesne, Lisa M. Boulanger, Susan B. Powell, Elaine Tierney, T M DeLorey, Yong-hui Jiang
Publikováno v:
Scopus-Elsevier
The broad variation in phenotypes and severities within autism spectrum disorders suggests the involvement of multiple predisposing factors, interacting in complex ways with normal developmental courses and gradients. Identification of these factors,
Autor:
Lisa M. Boulanger, Carolyn M. Tyler
Publikováno v:
Neuron. 74:597-599
Microglia are the resident CNS immune cells and active surveyors of the extracellular environment. While past work has focused on the role of these cells during disease, recent imaging studies reveal dynamic interactions between microglia and synapti