Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Lisa M. Barnhill"'
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract Long-term air pollution (AP) exposure, including diesel exhaust exposure, is increasingly being recognized as a major contributor to the development of neurodegenerative diseases such as Parkinson’s and Alzheimer’s disease. How AP increa
Externí odkaz:
https://doaj.org/article/f10f7d5d7297421e95f1173b777f60f1
Publikováno v:
Biomedicines, Vol 8, Iss 7, p 197 (2020)
Parkinson’s disease is a common neurodegenerative disorder leading to severe disability. The clinical features reflect progressive neuronal loss, especially involving the dopaminergic system. The causes of Parkinson’s disease are slowly being unc
Externí odkaz:
https://doaj.org/article/94be61a932354c38887f8b5c71f66f70
Autor:
Mitchell B. Diccianni, Alice L. Yu, Lei Bao, Minya Pu, Karen Messer, Jenna A. Mielke, Ayse Batova, Youngjin Kim, Olga Cohen, Richard T. Williams, Lisa M. Barnhill
CAI2, p16 and ARF expression in normal tissue compared to levels in fibroblasts (Supp Figure S1); Growth comparison of low vs. high passage NMB7 cells (Supp Figure S2); Growth comparison of low vs. high passage NMB7 cells in the absence of serum or p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fe769e2bc50ac999aa27a1368a1ec3b
https://doi.org/10.1158/0008-5472.22404552
https://doi.org/10.1158/0008-5472.22404552
Publikováno v:
Movement disorders : official journal of the Movement Disorder Society, vol 37, iss 5
Mov Disord
Mov Disord
Parkinson's disease, as well as other neurodegenerative disorders, are primarily characterized by pathological accumulation of proteins, inflammation, and neuron loss. Although there are some known genetic risk factors, most cases cannot be explained
Autor:
Jesus A. Araujo, Hiromi Murata, Sataree Khuansuwan, Jeff M. Bronstein, Lisa M. Barnhill, Daniel Juarez
Publikováno v:
Toxicological sciences : an official journal of the Society of Toxicology, vol 176, iss 1
Toxicol Sci
Toxicol Sci
The vast majority of neurodegenerative disease cannot be attributed to genetic causes alone and as a result, there is significant interest in identifying environmental modifiers of disease risk. Epidemiological studies have supported an association b
Autor:
Richard T Williams, Lisa M Barnhill, Huan-Hsien Kuo, Wen-Der Lin, Ayse Batova, Alice L Yu, Mitchell B Diccianni
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e88219 (2014)
The INK4A locus codes for two independent tumor suppressors, p14ARF and p16/CDKN2A, and is frequently mutated in many cancers. Here we report a novel deletion/substitution from CC to T in the shared exon 2 of p14ARF/p16 in a melanoma cell line. This
Externí odkaz:
https://doaj.org/article/7525970b81d64aeaa0ac840df7da95c6
Publikováno v:
Cell biology and toxicology.
Neurodegenerative diseases are a major cause of disability in the world, but their etiologies largely remain elusive. Genetic factors can only account for a minority of risk for most of these disorders, suggesting environmental factors play a signifi
Publikováno v:
Autophagy, vol 15, iss 8
The pathophysiology of most neurodegenerative diseases includes aberrant accumulation of protein aggregates. Recent evidence highlights the role of protein degradation pathways in neurodegeneration. Concurrently, genetic tools have been generated to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::927910b0158c5a8a217339c0520b5adf
Autor:
Alice L. Yu, Minya Pu, Richard T. Williams, Youngjin Kim, Lei Bao, Lisa M. Barnhill, Ayse Batova, Olga Cohen, J. Mielke, Mitchell B. Diccianni, Karen Messer
Publikováno v:
Cancer Research. 74:3753-3763
Neuroblastoma is a pediatric cancer with significant genomic and biologic heterogeneity. p16 and ARF, two important tumor-suppressor genes on chromosome 9p21, are inactivated commonly in most cancers, but paradoxically overexpressed in neuroblastoma.
Autor:
Binh Nguyen, Mark Stahl, Gal Bitan, Aaron Lulla, Lisa M. Barnhill, Kelley C. O’Donnell, Alvaro Sagasti, Magdalena I. Ivanova, Jeff M. Bronstein, Frank-Gerrit Klärner, Chase Yamashiro, Thomas Schrader
Publikováno v:
Environmental health perspectives, vol 124, iss 11
Environmental Health Perspectives
Lulla, A; Barnhill, L; Bitan, G; Ivanova, MI; Nguyen, B; O'Donnell, K; et al.(2016). Neurotoxicity of the Parkinson Disease-Associated Pesticide Ziram Is Synuclein-Dependent in Zebrafish Embryos. ENVIRONMENTAL HEALTH PERSPECTIVES, 124(11), 1766-1775. doi: 10.1289/EHP141. UCLA: Retrieved from: http://www.escholarship.org/uc/item/3rt4r391
Environmental Health Perspectives
Lulla, A; Barnhill, L; Bitan, G; Ivanova, MI; Nguyen, B; O'Donnell, K; et al.(2016). Neurotoxicity of the Parkinson Disease-Associated Pesticide Ziram Is Synuclein-Dependent in Zebrafish Embryos. ENVIRONMENTAL HEALTH PERSPECTIVES, 124(11), 1766-1775. doi: 10.1289/EHP141. UCLA: Retrieved from: http://www.escholarship.org/uc/item/3rt4r391
Background: Exposure to the commonly used dithiocarbamate (DTC) pesticides is associated with an increased risk of developing Parkinson disease (PD), although the mechanisms by which they exert their toxicity are not completely understood. Objective:
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa22c553942751b4804283ec69568ef7
https://escholarship.org/uc/item/3rt4r391
https://escholarship.org/uc/item/3rt4r391