Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Lisa M Sevilla"'
Autor:
Lisa M. Sevilla, Omar Pons-Alonso, Andrea Gallego, Mikel Azkargorta, Félix Elortza, Paloma Pérez
Publikováno v:
Cell Death and Disease, Vol 15, Iss 7, Pp 1-12 (2024)
Abstract Atopic dermatitis (AD), a prevalent chronic inflammatory disease with multifactorial etiology, features epidermal barrier defects and immune overactivation. Synthetic glucocorticoids (GCs) are widely prescribed for treating AD due to their a
Externí odkaz:
https://doaj.org/article/b6d04cdcb9aa4de59471d245c59418b1
Publikováno v:
PLoS ONE, Vol 7, Iss 1, p e29701 (2012)
Delayed wound healing is one of the most common secondary adverse effects associated to the therapeutic use of glucocorticoid (GC) analogs, which act through the ligand-dependent transcription factor GC-receptor (GR). GR function is exerted through D
Externí odkaz:
https://doaj.org/article/3b0ab5a17fa540bea7d6d57ece77275a
Autor:
Lisa M. Sevilla, Alba Jiménez-Panizo, Andrea Alegre-Martí, Eva Estébanez-Perpiñá, Carme Caelles, Paloma Pérez
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 18, p 10049 (2021)
Endogenous glucocorticoids (GCs) are steroid hormones that signal in virtually all cell types to modulate tissue homeostasis throughout life. Also, synthetic GC derivatives (pharmacological GCs) constitute the first-line treatment in many chronic inf
Externí odkaz:
https://doaj.org/article/577e6aa429154e5cbde6301eda4ad9f0
Autor:
Lisa M. Sevilla, Paloma Pérez
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Psoriasis is a prevalent chronic inflammatory human disease initiated by impaired function of immune cells and epidermal keratinocytes, resulting in increased cytokine production and hyperproliferation, leading to skin lesions. Overproduction of Th1-
Externí odkaz:
https://doaj.org/article/be54632448df449097c9d142cfc8d4d5
Autor:
Elena Carceller‐Zazo, Lisa M. Sevilla, Omar Pons‐Alonso, Álvaro Chiner‐Oms, Larbi Amazit, Thi An Vu, Géraldine Vitellius, Say Viengchareun, Iñaki Comas, Yan Jaszczyszyn, Montserrat Abella, Andrea Alegre‐Martí, Eva Estébanez‐Perpiñá, Marc Lombès, Paloma Pérez
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental BiologyREFERENCES. 37(1)
17 páginas, 6 figuras
Glucocorticoids (GCs) exert potent antiproliferative and anti-inflammatory properties, explaining their therapeutic efficacy for skin diseases. GCs act by binding to the GC receptor (GR) and the mineralocorticoid receptor
Glucocorticoids (GCs) exert potent antiproliferative and anti-inflammatory properties, explaining their therapeutic efficacy for skin diseases. GCs act by binding to the GC receptor (GR) and the mineralocorticoid receptor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9c637710d259351caaa258e6439428a
https://pubmed.ncbi.nlm.nih.gov/36527388
https://pubmed.ncbi.nlm.nih.gov/36527388
Autor:
Lisa M. Sevilla, Vicente Sentandreu, Iñaki Comas, Álvaro Chiner-Oms, Judit Bigas, Paloma Pérez
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Scientific Reports
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Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Scientific Reports
11 págs., 6 figuras. All data generated or analyzed during this study are included in this published article (and its SupplementaryInformation fles) at https://doi.org/10.1038/s41598-020-75853-5.
Glucocorticoid (GC) actions are mediated through
Glucocorticoid (GC) actions are mediated through
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1a53f17d318594ff1c8d66866f02456
http://hdl.handle.net/10261/222384
http://hdl.handle.net/10261/222384
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
instname
10 páginas, 5 figuras. Supplementary material is linked to the online version of the paper at https://doi.org/10.1016/j.jid.2020.03.933
The increased production of endogenous glucocorticoids (GCs) in the skin of the elderly population contribut
The increased production of endogenous glucocorticoids (GCs) in the skin of the elderly population contribut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d6c6ae4b4cf7a7320b01d7764c08d78
https://pubmed.ncbi.nlm.nih.gov/32199993
https://pubmed.ncbi.nlm.nih.gov/32199993
Autor:
Lisa M. Sevilla, Paloma Pérez
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
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Keratin
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Keratin
Capítulo de libro, 22 páginas, 2 figuras, 1 tabla
We also acknowledge funding support from MINECO, Spanish Government (grants SAF2014-59474-R and SAF2017-88046-R). We thank NURCAMEIN (SAF2015-71878-REDT and SAF2017-90604-REDT) for support for
We also acknowledge funding support from MINECO, Spanish Government (grants SAF2014-59474-R and SAF2017-88046-R). We thank NURCAMEIN (SAF2015-71878-REDT and SAF2017-90604-REDT) for support for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::665a4211a82a388b30c44e9f9c3647b0
https://doi.org/10.5772/intechopen.79458
https://doi.org/10.5772/intechopen.79458
Autor:
Lisa M. Sevilla, Paloma Pérez
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 7, p 1906 (2018)
International Journal of Molecular Sciences
International Journal of Molecular Sciences
The nuclear hormone receptor (NR) superfamily comprises approximately 50 evolutionarily conserved proteins that play major roles in gene regulation by prototypically acting as ligand-dependent transcription factors. Besides their central role in phys
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d14dee5f80ae681430e99adfb37710b
http://www.mdpi.com/1422-0067/19/7/1906
http://www.mdpi.com/1422-0067/19/7/1906
Publikováno v:
Cell Death & Disease
Cell Death and Disease, Vol 9, Iss 6, Pp 1-14 (2018)
Digital.CSIC. Repositorio Institucional del CSIC
instname
Cell Death and Disease, Vol 9, Iss 6, Pp 1-14 (2018)
Digital.CSIC. Repositorio Institucional del CSIC
instname
14 páginas, 6 figuras. Material suplementario en https://doi.org/10.1038/s41419-018-0673-z.
Endogenous and synthetic glucocorticoids (GCs) regulate epidermal development and combat skin inflammatory diseases. GC actions can be mediated through
Endogenous and synthetic glucocorticoids (GCs) regulate epidermal development and combat skin inflammatory diseases. GC actions can be mediated through
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38366926ac2c415c675db0cf36e5a49e
https://pubmed.ncbi.nlm.nih.gov/29789551
https://pubmed.ncbi.nlm.nih.gov/29789551