Zobrazeno 1 - 10 of 425 pro vyhledávání: '"Lisa M Miller"'
1
Akademický článek
A novel preventive strategy against HIV-1 infection: combinatorial use of inhibitors targeting the nucleocapsid and fusion proteinsCombination of SAMT10 and SFT against HIV-1
Autor: Yu Yang, Jingyu Zhu, Matthew Hassink, Lisa M Miller Jenkins, Yanmin Wan, Daniel H Appella, Jianqing Xu, Ettore Appella, Xiaoyan Zhang
Publikováno v: Emerging Microbes and Infections, Vol 6, Iss 1, Pp 1-8 (2017)
The strategy of simultaneously attacking multiple targets is worthy of exploration in the field of microbicide development to combat HIV-1 sequence diversity and minimize the transmission of resistant variants. A combination of S-acyl-2-mercaptobenza
Externí odkaz: https://doaj.org/article/a6e854552b20465ba205e513c3ff8a94
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2
Akademický článek
Unique properties of TCR-activated p38 are necessary for NFAT-dependent T-cell activation.
Autor: Muhammad S Alam, Matthias M Gaida, Subrata Debnath, Harichandra D Tagad, Lisa M Miller Jenkins, Ettore Appella, M Jubayer Rahman, Jonathan D Ashwell
Publikováno v: PLoS Biology, Vol 16, Iss 1, p e2004111 (2018)
Nuclear factor of activated T cells (NFAT) transcription factors are required for induction of T-cell cytokine production and effector function. Although it is known that activation via the T-cell antigen receptor (TCR) results in 2 critical steps, c
Externí odkaz: https://doaj.org/article/e18026c7426842a2b968df00dde7a2a2
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3
Akademický článek
Metal-Deficient Aggregates and Diminished Copper Found in Cells Expressing SOD1 Mutations that Cause ALS
Autor: Megan W Bourassa, Hilda eBrown, David R Borchelt, Stefan eVogt, Lisa M Miller
Publikováno v: Frontiers in Aging Neuroscience, Vol 6 (2014)
Disruptions in metal ion homeostasis have been described in association with amyotrophic lateral sclerosis (ALS) for a number of years but the precise mechanism of involvement is poorly understood. Metal ions are especially important to familial ALS
Externí odkaz: https://doaj.org/article/24372283a37e4d56a35f3ffaa505de28
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4
Akademický článek
Altered composition of bone as triggered by irradiation facilitates the rapid erosion of the matrix by both cellular and physicochemical processes.
Autor: Danielle E Green, Benjamin J Adler, Meilin Ete Chan, James J Lennon, Alvin S Acerbo, Lisa M Miller, Clinton T Rubin
Publikováno v: PLoS ONE, Vol 8, Iss 5, p e64952 (2013)
Radiation rapidly undermines trabecular architecture, a destructive process which proceeds despite a devastated cell population. In addition to the 'biologically orchestrated' resorption of the matrix by osteoclasts, physicochemical processes enabled
Externí odkaz: https://doaj.org/article/03d680522c7348a48ffe0f7f76542e88
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5
Akademický článek
RTL551 treatment of EAE reduces CD226 and T-bet+ CD4 T cells in periphery and prevents infiltration of T-bet+ IL-17, IFN-γ producing T cells into CNS.
Autor: Sushmita Sinha, Lisa M Miller, Sandhya Subramanian, Gregory G Burrows, Arthur A Vandenbark, Halina Offner
Publikováno v: PLoS ONE, Vol 6, Iss 7, p e21868 (2011)
Recombinant T cell receptor ligands (RTLs) that target encephalitogenic T-cells can reverse clinical and histological signs of EAE, and are currently in clinical trials for treatment of multiple sclerosis. To evaluate possible regulatory mechanisms,
Externí odkaz: https://doaj.org/article/efa463d5dd7c4dafa3b1ca06e7763029
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