Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Lisa M Johansen"'
Autor:
Charles J Shoemaker, Kathryn L Schornberg, Sue E Delos, Corinne Scully, Hassan Pajouhesh, Gene G Olinger, Lisa M Johansen, Judith M White
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e56265 (2013)
Ebola virus (EBOV) is an enveloped RNA virus that causes hemorrhagic fever in humans and non-human primates. Infection requires internalization from the cell surface and trafficking to a late endocytic compartment, where viral fusion occurs, providin
Externí odkaz:
https://doaj.org/article/e41b76c3bdb5499fbd5498b5ccc2905a
Autor:
Christopher M Owens, Christina Mawhinney, Jill M Grenier, Ralf Altmeyer, Margaret S Lee, Alexis A Borisy, Joseph Lehár, Lisa M Johansen
Publikováno v:
Molecular Systems Biology, Vol 6, Iss 1, Pp n/a-n/a (2010)
The search for effective Hepatitis C antiviral therapies has recently focused on host sterol metabolism and protein prenylation pathways that indirectly affect viral replication. However, inhibition of the sterol pathway with statin drugs has not yie
Externí odkaz:
https://doaj.org/article/b4b9b49657b3440dabf153426b420ffc
Autor:
Aidan O’Connor, Tero Aittokallio, Mary F. Paine, Shawn Herring, Qinfeng Huang, Lisa M. Johansen, Gene G. Olinger, Stephen J. Polyak, Judith M. White, Aleksandr Ianevski, Lisa Evans DeWald, Jessica Wagoner, Elizabeth A. Nelson, Jessica M. Oda, Yuying Liang, Pamela J. Glass, Susan L. Fink, Delaney Kirchmeier
Publikováno v:
Antimicrobial Agents and Chemotherapy
Neglected diseases caused by arenaviruses such as Lassa virus (LASV) and filoviruses like Ebola virus (EBOV) primarily afflict resource-limited countries, where antiviral drug development is often minimal. Previous studies have shown that many approv
Autor:
Joshua T. Schiffer, Craig J. Thomas, Xin Xu, Patrick Morris, Lisa E. Hensley, Elena Postnikova, Peter B. Jahrling, Lisa M. Johansen, Judith M. White, Lisa Evans DeWald, Elizabeth A. Nelson, Maria P. Arolfo, Michael R. Holbrook, Linh H. Nguyen, Courtney L. Finch, Amy Wang, Emma Hughes, Gene G. Olinger, Julie Dyall, Huanying Zhou, Shuang Xu, Bryan Koci, Janie Y. Liang, Connie S. Schmaljohn, Jon C. Mirsalis
Publikováno v:
Microorganisms
Volume 9
Issue 3
Microorganisms, Vol 9, Iss 566, p 566 (2021)
Volume 9
Issue 3
Microorganisms, Vol 9, Iss 566, p 566 (2021)
Outbreaks of Ebola ebolavirus (EBOV) have been associated with high morbidity and mortality. Milestones have been reached recently in the management of EBOV disease (EVD) with licensure of an EBOV vaccine and two monoclonal antibody therapies. Howeve
Autor:
Shawn Herring, Lisa Evans DeWald, Aidan O’Connor, Susan L. Fink, Mary F. Paine, Delaney Kirchmeier, Jessica M. Oda, Yuying Liang, Pamela J. Glass, Lisa M. Johansen, Tero Aittokallio, Stephen J. Polyak, Elizabeth A. Nelson, Aleksandr Ianevski, Jessica Wagoner, Gene G. Olinger, Qinfeng Huang, Judith M. White
Publikováno v:
Antimicrob Agents Chemother
Correction: Volume65, Issue6 Article Numbere00653- 21 DOI10.1128/AAC.00653-21 Neglected diseases caused by arenaviruses such as Lassa virus (LASV) and filoviruses like Ebola virus (EBOV) primarily afflict resource-limited countries, where antiviral d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41f2c246aa6f6cb83624ab13cf5c5009
http://hdl.handle.net/10852/92671
http://hdl.handle.net/10852/92671
Autor:
Charles J. Shoemaker, Kathryn L. Schornberg, Sue E. Delos, Corinne Scully, Hassan Pajouhesh, Gene G. Olinger, Lisa M. Johansen, Judith M. White
Publikováno v:
PLoS ONE, Vol 8, Iss 10 (2013)
Externí odkaz:
https://doaj.org/article/e9ff707137b94f6f833ef47273975822
Autor:
Ravit Geva, Antonio Jimeno, Khanh T. Do, S. Kummar, Manish R. Patel, Lisa M. Johansen, Stephanie Pascarella, Salomon M. Stemmer, Ruth Perets, Ding Wang, Patricia LoRusso, Sima Zacharek, Ryan J. Sullivan, Robert S. Meehan, Praveen Aanur, Sheryl Chen, Josh Frederick, Todd M. Bauer, Randy F. Sweis, Oleg Milberg, Shilpa Gupta, Andressa S. Laino, Patrick M. Reagan, William Randolph
Publikováno v:
Journal for ImmunoTherapy of Cancer. 9:A569-A569
BackgroundmRNA-2752 is a novel mRNA-based therapeutic agent encoding OX40L T cell co-stimulator, IL-23 and IL-36γ pro-inflammatory cytokines. Preclinical data demonstrate synergy in combination with PD-L1 blockade.MethodsThis study evaluated the saf
Autor:
Stephanie Pascarella, Lisa M. Johansen, Kurt A. Schalper, Todd M. Bauer, Ding Wang, Joshua Frederick, Robert S. Meehan, William Randolph, Jing Sun, Shilpa Gupta, Honghong Zhou, Khanh T. Do, Deanna Teoh, Andressa S. Laino, Wallace Akerley, Pamela S. Cohen, Ryan J. Sullivan, Sima Zacharek, Antonio Jimeno
Publikováno v:
Cancer Research. 80:CT032-CT032
Background: While PD-1/L1 blockade is an effective therapeutic approach for many patients with solid and hematologic malignancies, it is not sufficient to induce tumor regressions in the majority of patients. Optimal T cell responses require T cell r
Autor:
Richard S. Bennett, Crystal McKnight, Michael R. Holbrook, Judith M. White, Tim Mierzwa, Ian Crozier, Elena Postnikova, Julia Michelotti, Lisa M. Johansen, Pamela J. Glass, Carleen Klumpp-Thomas, Lisa Evans DeWald, Nicole Deiuliis, Craig J. Thomas, Julie Dyall, Rajarshi Guha, Paul Shinn, Brit J. Hart, Elizabeth A. Nelson, Gene G. Olinger, Huanying Zhou, Peter B. Jahrling, Walter M Vargas, Patrick J. Morris, Lisa E. Hensley, James Logue, Robin Gross
Publikováno v:
The Journal of infectious diseases. 218(suppl_5)
Background A need to develop therapeutics to treat Ebola virus disease patients in remote and resource-challenged settings remains in the wake of the 2013-2016 epidemic in West Africa. Toward this goal, we screened drugs under consideration as treatm
Autor:
Calli M. Lear-Rooney, Christopher M. Coleman, Lisa M. Johansen, Reed F. Johnson, Jason Kindrachuk, Gene G. Olinger, Lisa E. Hensley, Michael R. Holbrook, Matthew B. Frieman, Thiagarajan Venkataraman, Peter B. Jahrling, Pamela J. Glass, Monique Laidlaw, Julie Dyall, Brit J. Hart
Publikováno v:
Antimicrobial Agents and Chemotherapy
Outbreaks of emerging infections present health professionals with the unique challenge of trying to select appropriate pharmacologic treatments in the clinic with little time available for drug testing and development. Typically, clinicians are left