Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Lisa M Gutzwiller"'
Autor:
Ellen K Gagliani, Lisa M Gutzwiller, Yi Kuang, Yoshinobu Odaka, Phillipp Hoffmeister, Stefanie Hauff, Aleksandra Turkiewicz, Emily Harding-Theobald, Patrick J Dolph, Tilman Borggrefe, Franz Oswald, Brian Gebelein, Rhett A Kovall
Publikováno v:
PLoS Genetics, Vol 18, Iss 8, p e1010335 (2022)
Notch signaling is a conserved pathway that converts extracellular receptor-ligand interactions into changes in gene expression via a single transcription factor (CBF1/RBPJ in mammals; Su(H) in Drosophila). In humans, RBPJ variants have been linked t
Externí odkaz:
https://doaj.org/article/3d3ef8ff2e0245a7bfb1cb014a49f333
Autor:
Yi Kuang, Anna Pyo, Natanel Eafergan, Brittany Cain, Lisa M Gutzwiller, Ofri Axelrod, Ellen K Gagliani, Matthew T Weirauch, Raphael Kopan, Rhett A Kovall, David Sprinzak, Brian Gebelein
Publikováno v:
PLoS Genetics, Vol 17, Iss 9, p e1009039 (2021)
Notch signaling controls many developmental processes by regulating gene expression. Notch-dependent enhancers recruit activation complexes consisting of the Notch intracellular domain, the Cbf/Su(H)/Lag1 (CSL) transcription factor (TF), and the Mast
Externí odkaz:
https://doaj.org/article/46e826c091ea4d9db920f08826b85963
Publikováno v:
PLoS Genetics, Vol 14, Iss 4, p e1007289 (2018)
Cells use thousands of regulatory sequences to recruit transcription factors (TFs) and produce specific transcriptional outcomes. Since TFs bind degenerate DNA sequences, discriminating functional TF binding sites (TFBSs) from background sequences re
Externí odkaz:
https://doaj.org/article/300e3ec1252f4d3790dfcd6027aac3b1
Autor:
Ellen K. Gagliani, Lisa M. Gutzwiller, Yi Kuang, Yoshinobu Odaka, Phillipp Hoffmeister, Stefanie Hauff, Aleksandra Turkiewicz, Emily Harding-Theobald, Patrick J. Dolph, Tilman Borggrefe, Franz Oswald, Brian Gebelein, Rhett A. Kovall
Publikováno v:
PLoS genetics. 18(8)
Notch signaling is a conserved pathway that converts extracellular receptor-ligand interactions into changes in gene expression via a single transcription factor (CBF1/RBPJ in mammals; Su(H) in Drosophila). In humans, RBPJ variants have been linked t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67dce116c72ecde6d05251bcac93ec40
https://pubmed.ncbi.nlm.nih.gov/35951645
https://pubmed.ncbi.nlm.nih.gov/35951645
Autor:
Ellen K. Gagliani, Brian Gebelein, Tilman Borggrefe, Yi Kuang, Patrick J. Dolph, Rhett A. Kovall, Phillipp Hoffmeister, Aleksandra Turkiewicz, Emily Harding-Theobald, Yoshinobu Odaka, Franz Oswald, Stefanie Hauff, Lisa M. Gutzwiller
Notch signaling is a conserved pathway that converts extracellular receptor-ligand interactions into changes in gene expression via a single transcription factor (CBF1/RBPJ in mammals; Su(H) in Drosophila). In humans, RBPJ variants have been linked t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::48a3d161f94cc06c845756d7f7deccc1
https://doi.org/10.1101/2021.09.24.461537
https://doi.org/10.1101/2021.09.24.461537
Autor:
Xinjian Wang, Matthias Eckenweiler, Peter Hedera, Michael Zech, Juliane Winkelmann, Donald L. Gilbert, Derek E. Neilson, Shelli M. Homan, Jesse Slone, Nancy D. Leslie, Brian Gebelein, Lisa M. Gutzwiller, Jianfeng Xiao, Taosheng Huang, Robert B. Hufnagel, Elizabeth J. Leslie, Mark S. LeDoux, Friederike Wilbert
Publikováno v:
Mov Disord
BACKGROUND In a large pedigree with an unusual phenotype of spastic paraplegia or dystonia and autosomal dominant inheritance, linkage analysis previously mapped the disease to chromosome 2q24-2q31. OBJECTIVE The aim of this study is to identify the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c945930024c6953a2c0aaf6f5bc6f26f
https://pubmed.ncbi.nlm.nih.gov/34636445
https://pubmed.ncbi.nlm.nih.gov/34636445
Autor:
Brian Gebelein, Ellen K. Gagliani, Raphael Kopan, Natanel Eafergan, Rhett A. Kovall, Yi Kuang, Matthew T. Weirauch, Anna Pyo, Brittany Cain, Lisa M. Gutzwiller, Ofri Axelrod, David Sprinzak
Publikováno v:
PLoS Genetics, Vol 17, Iss 9, p e1009039 (2021)
PLoS Genetics
PLoS Genetics
Notch signaling controls many developmental processes by regulating gene expression. Notch-dependent enhancers recruit activation complexes consisting of the Notch intracellular domain, the Cbf/Su(H)/Lag1 (CSL) transcription factor (TF), and the Mast
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de114790586f27d05d91e1e85e0921ad
https://doaj.org/article/46e826c091ea4d9db920f08826b85963
https://doaj.org/article/46e826c091ea4d9db920f08826b85963
Autor:
Amy L Gresser, Lisa M Gutzwiller, Mackenzie K Gauck, Volker Hartenstein, Tiffany A Cook, Brian Gebelein
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0134915 (2015)
Organismal growth regulation requires the interaction of multiple metabolic, hormonal and neuronal pathways. While the molecular basis for many of these are well characterized, less is known about the developmental origins of growth regulatory struct
Externí odkaz:
https://doaj.org/article/6f62a1005f4448498d1793ce9f3625b2
Publikováno v:
PLoS Genetics
PLoS Genetics, Vol 13, Iss 7, p e1006910 (2017)
PLoS Genetics, Vol 13, Iss 7, p e1006910 (2017)
Hox transcription factors specify distinct cell types along the anterior-posterior axis of metazoans by regulating target genes that modulate signaling pathways. A well-established example is the induction of Epidermal Growth Factor (EGF) signaling b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0d8d06645bb3552d336260072f276ec
http://europepmc.org/articles/PMC5536354
http://europepmc.org/articles/PMC5536354
Publikováno v:
Development Genes and Evolution. 222:77-88
Oenocytes are a specialized cell type required for lipid processing, pheromone secretion, and developmental signaling. Their development has been well characterized in Drosophila melanogaster, but it remains unknown whether the developmental program
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad857d64420c2673570452c9b60eb891
https://doi.org/10.1007/s00427-012-0390-z
https://doi.org/10.1007/s00427-012-0390-z