Zobrazeno 1 - 10 of 11 pro vyhledávání: '"Lisa M Grady"'
1
Shiftwork and the Retinal Vasculature Diameters Among Police Officers
Autor: Lisa M. Grady, Anna Mnatsakanova, Ronald Klein, Ja K. Gu, Michael E. Andrew, John M. Violanti, Luenda E. Charles, Desta Fekedulegn, Claudia C. Ma
Publikováno v: Journal of Occupational & Environmental Medicine. 59:e172-e179
Objective To investigate associations of central retinal arteriolar equivalent (CRAE), a measure of retinal arteriolar width, and central retinal venular equivalents (CRVE), a measure of retinal venular width, with shiftwork in 199 police officers (7
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6953906d8c51e0b9ca6afea63d9612d1
https://doi.org/10.1097/jom.0000000000001136
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2
Association Between Blood Pressure and Retinal Vessel Diameters Among Police Officers in the US Northeast
Autor: Lisa M. Grady, Penelope Allison, John M. Violanti, Claudia C. Ma, Ja K. Gu, Ronald Klein, Luenda E. Charles, Michael E. Andrew
Publikováno v: Journal of occupational and environmental medicine. 60(3)
The aim of this study was to examine relationships of blood pressure with central retinal arteriolar equivalent (CRAE) and central retinal venular equivalent (CRVE) among 242 police officers.Computerized retinal images of each eye were taken. Mean va
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c10dc906da7fc5f7945b6273ef3c9b3e
https://pubmed.ncbi.nlm.nih.gov/29227361
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3
High quality clinical grade human embryonic stem cell lines derived from fresh discarded embryos
Autor: Alan Kerby, Clare Edmond, Despina Soteriou, Tope Adeniyi, Kay Poulton, Lisa M Grady, Ronnie Wright, Marcus Lowe, Susan J. Kimber, Nicola Bates, Alex Ross, Jinpei Ye, Daniel R Brison, Philip A. Lewis
Publikováno v: Ye, J, Bates, N, Soteriou, D, Grady, L, Edmond, C, Ross, A, Kerby, A, Lewis, P A, Adeniyi, T, Wright, R, Poulton, K V, Lowe, M, Kimber, S J & Brison, D R 2017, ' High quality clinical grade human embryonic stem cell lines derived from fresh discarded embryos ', Stem Cell Research & Therapy, vol. 8, no. 1, 128, pp. 1-13 . https://doi.org/10.1186/s13287-017-0561-y
Stem Cell Research & Therapy, Vol 8, Iss 1, Pp 1-13 (2017)
Stem Cell Research & Therapy
Background Human embryonic stem cells (hESCs) hold tremendous promise for cell replacement therapies for a range of degenerative diseases. In order to provide cost-effective treatments affordable by public health systems, HLA-matched allogeneic tissu
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd76377dadc5fa87093da926e7f74fed
https://doi.org/10.1186/s13287-017-0561-y
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4
IL-27 Receptor Signaling Regulates Memory CD4 + T Cell Populations and Suppresses Rapid Inflammatory Responses during Secondary Malaria Infection
Autor: Emily Gwyer Findlay, Ana Villegas-Mendez, J. Brian de Souza, Eleanor M. Riley, Lisa M Grady, Noelle O'Regan, Christiaan J. M. Saris, Kevin N. Couper
Publikováno v: Infection and Immunity. 82:10-20
Interleukin-27 (IL-27) is known to control primary CD4 + T cell responses during a variety of different infections, but its role in regulating memory CD4 + T responses has not been investigated in any model. In this study, we have examined the functi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ed2fbe063d501286589bda591341537
https://doi.org/10.1128/iai.01091-13
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5
Chondrogenic Differentiation of Human Bone Marrow Stem Cells in Transwell Cultures: Generation of Scaffold-Free Cartilage
Autor: Timothy E. Hardingham, Matthew P. Ablett, Theoni Katopodi, Lisa M Grady, Alan D. Murdoch, Roger S. Meadows
Publikováno v: Stem Cells. 25:2786-2796
Human bone marrow stem cells (hMSCs) have been shown to differentiate in vitro into a number of cell lineages and are a potential autologous cell source for the repair and replacement of damaged and diseased musculoskeletal tissues. hMSC differentiat
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3df129fab7382fff8142252639c6ca25
https://doi.org/10.1634/stemcells.2007-0374
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7
Directed differentiation of human embryonic stem cells toward chondrocytes
Autor: Timothy E. Hardingham, Lisa M Grady, Emma T. Lowe, Nicola Bates, Francesca Soncin, Melissa A. Baxter, Daniel R. Brison, Susan J. Kimber, Rachel A. Oldershaw
Publikováno v: Nature biotechnology. 28(11)
We report a chemically defined, efficient, scalable and reproducible protocol for differentiation of human embryonic stem cells (hESCs) toward chondrocytes. HESCs are directed through intermediate developmental stages using substrates of known matrix
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::269c3eb051a9a9fece616d03aed899c3
https://pubmed.ncbi.nlm.nih.gov/20967028
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8
Human meniscus cells express hypoxia inducible factor-1alpha and increased SOX9 in response to low oxygen tension in cell aggregate culture
Autor: S Jane Millward-Sadler, Wasim S. Khan, Adetola B Adesida, Donald Salter, Lisa M Grady, Timothy E. Hardingham
Publikováno v: Arthritis Research & Therapy
Adesida, A B, Grady, L M, Khan, W S, Millward-Sadler, S J, Salter, D M & Hardingham, T E 2007, ' Human meniscus cells express hypoxia inducible factor-1alpha and increased SOX9 in response to low oxygen tension in cell aggregate culture ', Arthritis Research and Therapy, vol. 9, no. 4, pp. R69 . https://doi.org/10.1186/ar2267
In previous work we demonstrated that the matrix-forming phenotype of cultured human cells from whole meniscus was enhanced by hypoxia (5% oxygen). Because the meniscus contains an inner region that is devoid of vasculature and an outer vascular regi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa568958bdf795035e6f4080bfe48c6e
https://pubmed.ncbi.nlm.nih.gov/17640365
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9
WSX-1 Signalling Inhibits CD4+ T Cell Migration to the Liver during Malaria Infection by Repressing Chemokine-Independent Pathways
Autor: Lisa M Grady, Kevin N. Couper, Emily Gwyer Findlay, Eleanor M. Riley, Christiaan J. M. Saris, Thomas E. Lane, Ana Villegas-Mendez, J. Brian de Souza
Publikováno v: PLoS ONE
PLoS ONE, Vol 8, Iss 11, p e78486 (2013)
Villegas-Mendez, A, Gwyer Findlay, E, de Souza, J B, Grady, L-M, Saris, C J, Lane, T E, Riley, E M & Couper, K N 2013, ' WSX-1 signalling inhibits CD4⁺ T cell migration to the liver during malaria infection by repressing chemokine-independent pathways ', PLoS ONE, vol. 8, no. 11, e78486 . https://doi.org/10.1371/journal.pone.0078486
IL-27 is an important and non-redundant regulator of effector T cell accumulation in non-lymphoid tissues during infection. Using malaria as a model systemic pro-inflammatory infection, we demonstrate that the aberrant accumulation of CD4⁺ T cells
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c2568ad6c28b6771dd2dce8b3ab0b02
https://doi.org/10.1371/journal.pone.0078486
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10
Statin Use and Incident Nuclear Cataract
Autor: Kristine E. Lee, Lisa M. Grady, Barbara E.K. Klein, Ronald Klein
Publikováno v: JAMA. 295:2752
ContextStatins are widely prescribed for their lipid-lowering effects but also have putative antioxidant properties. Oxidative stress is believed to play a role in the development of nuclear cataract, but little is known regarding the relationship of
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fbc2abbe876e0f9913fde2cbf8f8759
https://doi.org/10.1001/jama.295.23.2752
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