Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Lisa M Dauffenbach"'
Autor:
Shafaat A. Rabbani, Bushra Ateeq, Ani Arakelian, Maria Luisa Valentino, David E. Shaw, Lisa M. Dauffenbach, Christopher A. Kerfoot, Andrew P. Mazar
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 12, Iss 10, Pp 778-788 (2010)
Urokinase plasminogen activator receptor (uPAR) is a multidomain protein that plays important roles in the growth, invasion, and metastasis of a number of cancers. In the present study, we examined the effects of administration of a monoclonal anti-u
Externí odkaz:
https://doaj.org/article/1f6a07b9a2a84b47b51d91ef32061796
Autor:
Christopher A. Kerfoot, Andrew P. Mazar, Ani Arakelian, Bushra Ateeq, Lisa M. Dauffenbach, Shafaat A. Rabbani, Maria-Luisa Valentino, David E. Shaw
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 12, Iss 10, Pp 778-788 (2010)
Urokinase plasminogen activator receptor (uPAR) is a multidomain protein that plays important roles in the growth, invasion, and metastasis of a number of cancers. In the present study, we examined the effects of administration of a monoclonal anti-u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::872a320813f20ad9fe80b718a1b0c615
http://www.sciencedirect.com/science/article/pii/S1476558610800454
http://www.sciencedirect.com/science/article/pii/S1476558610800454
Autor:
Jan Lesniak, Alexei Budco, Svenja Lippok, Christopher A. Kerfoot, Katrin Schneider, Gela Sia, Anthony Masci, Dasa Medrikova, Tobias Wiestler, René Korn, Florian Leiß, Lisa M. Dauffenbach, Johannes Zimmermann
Publikováno v:
Molecular Cancer Therapeutics. 17:B069-B069
Definiens and Mosaic Laboratories developed an immuno-oncology (IO) panel consisting of multiplex chromogenic IHC assays and image and data analysis solutions to determine a standardized profile of the tumor microenvironment in non-small cell lung ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::29a1c4dbc3f38c564786995f892a6966
https://doi.org/10.1158/1535-7163.targ-17-b069
https://doi.org/10.1158/1535-7163.targ-17-b069
Autor:
Scott Jepson, Youssef L. Bennani, Lisa M Dauffenbach, James K. Hogan, J. Daniel Frantz, Albert C. Pierce, Francesco G. Salituro, Bin Fan, Tiansheng Wang, Jian Wang, James Black, Mark Wood, Yong Gu, Brinley Furey, Harmon J. Zuccola, Dina Shlyakter, Thomas Hoock, Ursula A. Germann, Summer Halas, Sudipta Mahajan, Mark W. Ledeboer, Mark N. Namchuk, John P. Duffy
Publikováno v:
Journal of Medicinal Chemistry. 52:7938-7941
The synthesis and characterization of a novel polycyclic azaindole based derivative is disclosed, and its binding to JAK2 is described. The compound is further evaluated for its ability to block the EPO/JAK2 signaling cascade in vitro and in vivo.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02668d489255841e033a2b40c32efc3b
https://doi.org/10.1021/jm901383u
https://doi.org/10.1021/jm901383u
Autor:
Natalia Jun, Lisa M. Dauffenbach, Christopher A. Kerfoot, Gela C. Sia, Eric Olsen, Jianping Zheng
Publikováno v:
Cancer Research. 77:4009-4009
Tumor-associated macrophages play an important role in presenting tumor antigens to T cells and are being investigated for their role in sensitivity to immune checkpoint inhibitors such as PD-1 inhibitors. The M2 macrophage subtype, characterized by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a9421e4efb948be8bd456ba45b019b51
https://doi.org/10.1158/1538-7445.am2017-4009
https://doi.org/10.1158/1538-7445.am2017-4009
Autor:
Natalia Jun, Christopher A. Kerfoot, Lisa M. Dauffenbach, Jianping Zheng, Eric Olsen, Gela C. Sia
Publikováno v:
Cancer Research. 77:1669-1669
Evaluating the density of immune cell subtypes and their relative spatial positioning in cancers has become an important tool in understanding response to immune checkpoint inhibitors. The purpose of this study was to investigate protein expression o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f9180f492f79ad113a17a15f888e4978
https://doi.org/10.1158/1538-7445.am2017-1669
https://doi.org/10.1158/1538-7445.am2017-1669
Autor:
Christina George, Deog Joong Kim, Chang-Ho Ahn, Julie Frank, Lisa M. Dauffenbach, Young Bok Lee, Reza Mazhari, Eric Olsen
Publikováno v:
Cancer Research. 77:1790-1790
Background: A novel, orally bioavailable nucleoside analogue, RX-3117, is a prodrug activated intracellularly by Uridine Cytidine Kinase 2 (UCK2) that is thought to be expressed predominantly in tumor tissue. RX-3117 is currently being evaluated in a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::405b65659d32df84b0902ab590d59cab
https://doi.org/10.1158/1538-7445.am2017-1790
https://doi.org/10.1158/1538-7445.am2017-1790
Publikováno v:
Cancer Research. 76:1373-1373
Introduction: NY-ESO-1 is a cancer testis antigen frequently expressed in a broad range of tumors: lung, breast, ovarian, bladder, liver cancer, melanoma, sarcoma and myeloma. CDX-1401, a fully human monoclonal antibody linked to full length NY-ESO-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6da445a20c8f3338a42335cc1e345d69
https://doi.org/10.1158/1538-7445.am2016-1373
https://doi.org/10.1158/1538-7445.am2016-1373
Autor:
Jared Lunceford, Peter Strack, Christopher A. Kerfoot, Wei Zhou, Lisa M. Dauffenbach, Amy Sun
Publikováno v:
BMJ Open
Objectives Anti-phosphorylated histone H3 (pHH3) antibodies specifically detect the core protein histone H3 only when phosphorylated at serine 10 (Ser10) or serine 28 (Ser28). Measurement of pHH3 levels can be used for quantifying mitosis and the eff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::924fd860125fe4396f7da511b7bc5808
https://pubmed.ncbi.nlm.nih.gov/23065444
https://pubmed.ncbi.nlm.nih.gov/23065444
Autor:
Gela C. Sia, Christopher A. Kerfoot, Jianping Zheng, Eric Olsen, Ryan S. Lim, Sherif K. Girees, Patricia A. Cash, Lisa M. Dauffenbach
Publikováno v:
Cancer Research. 74:899-899
The PI3K and MEK pathways promote tumor cell survival through a variety of downstream signals and are commonly explored in cancer research. Many agents are in clinical development and new evidence suggests that a combination of these inhibitors may b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::90b50a9797371b71fb80673e3c30633a
https://doi.org/10.1158/1538-7445.am2014-899
https://doi.org/10.1158/1538-7445.am2014-899