Výsledky vyhledávání - "Lisa M, Pitchford"

Akademický článek

2-Hydroxybenzylamine (2-HOBA) to prevent early recurrence of atrial fibrillation after catheter ablation: protocol for a randomized controlled trial including detection of AF using a wearable device

Autor: Matthew J. O’Neill, Zachary T. Yoneda, Diane M. Crawford, Fei Ye, Mingfang Ao, Lisa M. Pitchford, John A. Rathmacher, Katherine T. Murray, Wendell S. Akers, Dan M. Roden, Gregory F. Michaud, M. Benjamin Shoemaker

Publikováno v: Trials, Vol 22, Iss 1, Pp 1-13 (2021)

Abstract Background Although catheter ablation is an effective therapy for atrial fibrillation (AF), the most common cardiac arrhythmia encountered in clinical practice, AF ablation generates inflammation and oxidative stress in the early postoperati

Externí odkaz: https://doaj.org/article/cf7ac91b8865459aa116294be6583ba3

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Akademický článek

Safety, tolerability, and pharmacokinetics of repeated oral doses of 2-hydroxybenzylamine acetate in healthy volunteers: a double-blind, randomized, placebo-controlled clinical trial

Autor: Lisa M. Pitchford, Patricia M. Driver, John C. Fuller, Wendell S. Akers, Naji N. Abumrad, Venkataraman Amarnath, Ginger L. Milne, Sheau-Chiann Chen, Fei Ye, L. Jackson Roberts, M. Benjamin Shoemaker, John A. Oates, John A. Rathmacher, Olivier Boutaud

Publikováno v: BMC Pharmacology and Toxicology, Vol 21, Iss 1, Pp 1-10 (2020)

Abstract Background 2-Hydroxybenzylamine (2-HOBA) is a selective dicarbonyl electrophile scavenger being developed as a nutritional supplement to help protect against the development of conditions associated with dicarbonyl electrophile formation, su

Externí odkaz: https://doaj.org/article/aa4bb108a03440a0be1f206802adc5d2

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Akademický článek

First-in-human study assessing safety, tolerability, and pharmacokinetics of 2-hydroxybenzylamine acetate, a selective dicarbonyl electrophile scavenger, in healthy volunteers

Autor: Lisa M. Pitchford, John A. Rathmacher, John C. Fuller, J. Scott Daniels, Ryan D. Morrison, Wendall S. Akers, Naji N. Abumrad, Venkataraman Amarnath, Patricia M. Currey, L. Jackson Roberts, John A. Oates, Olivier Boutaud

Publikováno v: BMC Pharmacology and Toxicology, Vol 20, Iss 1, Pp 1-6 (2019)

Abstract Background 2-Hydroxybenzylamine (2-HOBA) is a selective scavenger of dicarbonyl electrophiles that protects proteins and lipids from being modified by these electrophiles. It is currently being developed for use as a nutritional supplement t

Externí odkaz: https://doaj.org/article/7d1b0bf81dba4f70ab70f69755a8bc57

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Akademický článek

Health and ergogenic potential of oral adenosine-5′-triphosphate (ATP) supplementation

Autor: Ralf Jäger, Martin Purpura, John A. Rathmacher, John C. Fuller, Jr., Lisa M. Pitchford, Fabricio E. Rossi, Chad M. Kerksick

Publikováno v: Journal of Functional Foods, Vol 78, Iss , Pp 104357- (2021)

Adenosine triphosphate (ATP) is the primary compound that provides energy to drive many processes in living cells, including muscle contraction, neurotransmission, and cardiac function. Initial research used enteric-coated ATP that displayed no appar

Externí odkaz: https://doaj.org/article/838be89151de40eb91362ab1e2a05eb6

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Exercise training remodels subcutaneous adipose tissue in adults with obesity even without weight loss

Autor: Cheehoon Ahn, Benjamin J. Ryan, Michael W. Schleh, Pallavi Varshney, Alison C. Ludzki, Jenna B. Gillen, Douglas W. Van Pelt, Lisa M. Pitchford, Suzette M. Howton, Thomas Rode, Scott L. Hummel, Charles F. Burant, Jonathan P. Little, Jeffrey F. Horowitz

Publikováno v: The Journal of Physiology. 600:2127-2146

Excessive adipose tissue mass underlies much of the metabolic health complications in obesity. Although exercise training is known to improve metabolic health in individuals with obesity, the effects of exercise training without weight loss on adipos

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24ad038f3dd0d22264e56845587f9640
https://doi.org/10.1113/jp282371

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Small-Scale Randomized Controlled Trial to Explore the Impact of β-Hydroxy-β-Methylbutyrate Plus Vitamin D3 on Skeletal Muscle Health in Middle Aged Women

Autor: William D. Fairfield, Dennis M. Minton, Christian J. Elliehausen, Alexander D. Nichol, Taylor L. Cook, John A. Rathmacher, Lisa M. Pitchford, Scott A. Paluska, Adam J. Kuchnia, Jacob M. Allen, Adam R. Konopka

Publikováno v: Nutrients; Volume 14; Issue 21; Pages: 4674

β-Hydroxy-β-methylbutyrate (HMB), a leucine metabolite, can increase skeletal muscle size and function. However, HMB may be less effective at improving muscle function in people with insufficient Vitamin D3 (25-OH-D < 30 ng/mL) which is common in m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bca0ab9de0373da2ae94b24f1fce2997

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2-Hydroxybenzylamine (2-HOBA) to prevent early recurrence of atrial fibrillation after catheter ablation: protocol for a randomized controlled trial including detection of AF using a wearable device

Autor: Wendell S. Akers, Gregory F. Michaud, Lisa M. Pitchford, Katherine T. Murray, Zachary T. Yoneda, Fei Ye, Diane M. Crawford, Dan M. Roden, John A. Rathmacher, M. Benjamin Shoemaker, Matthew J. O’Neill, Mingfang Ao

Publikováno v: Trials
Trials, Vol 22, Iss 1, Pp 1-13 (2021)

Background Although catheter ablation is an effective therapy for atrial fibrillation (AF), the most common cardiac arrhythmia encountered in clinical practice, AF ablation generates inflammation and oxidative stress in the early postoperative period

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ffc122b2625262c31dc2f8c07452e68
https://pubmed.ncbi.nlm.nih.gov/34454591

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