Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Lisa M, Assmus"'
Autor:
Kylie M. Quinn, Tabinda Hussain, Felix Kraus, Luke E. Formosa, Wai K. Lam, Michael J. Dagley, Eleanor C. Saunders, Lisa M. Assmus, Erica Wynne-Jones, Liyen Loh, Carolien E. van de Sandt, Lucy Cooper, Kim L. Good-Jacobson, Katherine Kedzierska, Laura K. Mackay, Malcolm J. McConville, Georg Ramm, Michael T. Ryan, Nicole L. La Gruta
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Fatty acid oxidation (FAO) is thought to contribute to high spare respiratory capacity (SRC), which in turn affects CD8+ T cell function. Here, the authors show that ex vivo virtual memory T cells (and not antigen experienced memory T cells) have hig
Externí odkaz:
https://doaj.org/article/6da73ceced984a059e48b4f7619a183a
Autor:
Carl-Philipp Hackstein, Jasper Spitzer, Konstantinos Symeonidis, Helena Horvatic, Tanja Bedke, Babett Steglich, Sabine Klein, Lisa M. Assmus, Alexandru Odainic, Jennifer Szlapa, Nina Kessler, Marc Beyer, Ricarda Schmithausen, Eicke Latz, Richard A. Flavell, Natalio Garbi, Christian Kurts, Beate M. Kümmerer, Jonel Trebicka, Axel Roers, Samuel Huber, Susanne V. Schmidt, Percy A. Knolle, Zeinab Abdullah
Publikováno v:
Journal of hepatology 79(1), 150-166 (2023). doi:10.1016/j.jhep.2023.02.026
Patients with chronic liver disease (CLD), including cirrhosis, are at increased risk of intractable viral infections and are hyporesponsive to vaccination. Hallmarks of CLD and cirrhosis include microbial translocation and elevated levels of type I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df921c92fa9ddf3262c769c09b978293
https://doi.org/10.1016/j.jhep.2023.02.026
https://doi.org/10.1016/j.jhep.2023.02.026
Autor:
Kylie M. Quinn, Tabinda Hussain, Felix Kraus, Luke E. Formosa, Wai K. Lam, Michael J. Dagley, Eleanor C. Saunders, Lisa M. Assmus, Erica Wynne-Jones, Liyen Loh, Carolien E. van de Sandt, Lucy Cooper, Kim L. Good-Jacobson, Katherine Kedzierska, Laura K. Mackay, Malcolm J. McConville, Georg Ramm, Michael T. Ryan, Nicole L. La Gruta
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-1 (2020)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://doaj.org/article/4bb3b23071da4efa94de40dde3087b1f
Autor:
Carl-Philipp Hackstein, Jasper Spitzer, Konstantinos Symeonidis, Helena Horvatic, Tanja Bedke, Babett Steglich, Lisa M. Assmus, Alexandru Odainic, Nina Kessler, Sabine Klein, Marc Beyer, Ricarda Schmithausen, Eicke Latz, Christian Kurts, Jonel Trebicka, Richard A. Flavell, Natalio Garbi, Axel Roers, Samuel Huber, Susanne V. Schmidt, Percy A. Knolle, Zeinab Abdullah
Patients with liver injury such as cirrhosis are at increased risk of intractable viral infections and are hyporesponsive to vaccination. Here, we report that liver injury leads to inhibition of systemic T cell immunity (LIST), which abrogated anti-v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::082dc111a50b5ab388ebe0a9f4e038b1
https://doi.org/10.1101/2022.07.21.501031
https://doi.org/10.1101/2022.07.21.501031
Autor:
Ting Wu, Nicole L. La Gruta, Angela Nguyen, Andrea T. Nguyen, Jamie Rossjohn, Anthony W. Purcell, David C. Tscharke, Stephanie Gras, Xavier Y.X. Sng, C. Farenc, Pirooz Zareie, Lisa M Assmus, Nathan P. Croft, Jing Guan, Paul G. Thomas
Publikováno v:
The Journal of Immunology. 205:1731-1742
The presentation of pathogen-derived peptides on MHC class I molecules is essential for the initiation of adaptive CD8+ T cell immunity, which in turn is critical for effective control of many significant human infections. The identification of immun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::478dc83fb329817a1a493a5f6c95f77c
https://doi.org/10.4049/jimmunol.2000689
https://doi.org/10.4049/jimmunol.2000689
Autor:
Xavier Y.X. Sng, Claerwen M. Jones, Stephen J. Turner, Stephen R. Daley, Jason K.C. Lee, Pirooz Zareie, Kylie M. Quinn, Lisa M Assmus, Jasmine Li, Nicole L. La Gruta
Publikováno v:
The Journal of Immunology. 204:3108-3116
Naive CD8+ T cell survival in the periphery is critically dependent on tonic TCR signaling through peptide + MHC class I (MHCI) recognition; however, little is known about how natural variation in MHCI levels impacts the naive CD8+ T cell repertoire.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cb1f8b5c9d9d89ade82f3b8c51b0d839
https://doi.org/10.4049/jimmunol.2000081
https://doi.org/10.4049/jimmunol.2000081
Autor:
Erica Wynne-Jones, Kylie M. Quinn, Lisa M Assmus, Kim L. Good-Jacobson, Laura K. Mackay, Carolien E. van de Sandt, Georg Ramm, Wai K Lam, Tabinda Hussain, Michael J Dagley, Nicole L. La Gruta, Liyen Loh, Malcolm J. McConville, Katherine Kedzierska, Michael T. Ryan, Lucy Cooper, Felix Kraus, Luke E. Formosa, Eleanor C Saunders
Publikováno v:
Nature communications, 11(1):2857. Nature Publishing Group
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Virtual memory T (TVM) cells are antigen-naïve CD8+ T cells that exist in a semi-differentiated state and exhibit marked proliferative dysfunction in advanced age. High spare respiratory capacity (SRC) has been proposed as a defining metabolic chara
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85b9d439a40478ff5044380707195fc4
https://doi.org/10.1038/s41467-020-16633-7
https://doi.org/10.1038/s41467-020-16633-7
Autor:
Lisa M, Assmus, Jing, Guan, Ting, Wu, Carine, Farenc, Xavier Y X, Sng, Pirooz, Zareie, Angela, Nguyen, Andrea T, Nguyen, David C, Tscharke, Paul G, Thomas, Jamie, Rossjohn, Stephanie, Gras, Nathan P, Croft, Anthony W, Purcell, Nicole L, La Gruta
Publikováno v:
J Immunol
The presentation of pathogen-derived peptides on Major Histocompatibility Complex class I (MHCI) molecules is essential for the initiation of adaptive CD8(+) T cell immunity, which in turn is critical for effective control of many significant human i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c431ad1952074a5fc89a9eefb2510837
https://pubmed.ncbi.nlm.nih.gov/32868409
https://pubmed.ncbi.nlm.nih.gov/32868409
Autor:
Michael J Dagley, Erica Wynne-Jones, Laura K. Mackay, Felix Kraus, Georg Ramm, Wai K Lam, Kylie M. Quinn, Lisa M Assmus, Malcolm J. McConville, Luke E. Formosa, Michael T. Ryan, Katherine Kedzierska, Liyen Loh, Carolien E. van de Sandt, Nicole L. La Gruta, Lucy Cooper, Eleanor C Saunders, Tabinda Hussain, Kim L. Good-Jacobson
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-1 (2020)
Nature Communications
Nature Communications
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a2256706f494b8474fb75db00a16a51
http://link.springer.com/article/10.1038/s41467-020-17441-9
http://link.springer.com/article/10.1038/s41467-020-17441-9