Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Lisa L. Pundt"'
Publikováno v:
Cell Transplantation, Vol 5 (1996)
The use of human fetal tissue from elective abortions for cell transplantation therapies has been the subject of considerable controversy. Because of concerns regarding the use of tissue from elective abortions, tissue from spontaneous abortions has
Externí odkaz:
https://doaj.org/article/393a223375c54f4590457d128cf4cf91
Publikováno v:
Neuroscience Research. 24:415-420
Previous studies have demonstrated that syngeneic transplants of striatal tissue can ameliorate locomotor deficits in rodent models of Huntington's disease (HD). In the present study, we have examined whether human to rat xenografts of fetal striatal
Publikováno v:
Cell Transplantation, Vol 5 (1996)
The use of human fetal tissue from elective abortions for cell transplantation therapies has been the subject of considerable controversy. Because of concerns regarding the use of tissue from elective abortions, tissue from spontaneous abortions has
Publikováno v:
Molecular and Chemical Neuropathology. 20:81-96
Unilateral lesions by a cholinotoxin, receptor autoradiography, and in situ hybridization techniques were employed to determine if dopaminergic receptors are located on cholinergic interneurons in the caudate-putamen (CPu). Lesion of the CPu with sma
Publikováno v:
Neuroscience research. 27(4)
Huntington's Disease (HD) is characterized by deficits in motor and cognitive functions. This neurodegenerative disease shows an extensive loss of medium-sized spiny projection neurons (GABAergic) within the neostriatum. With the loss of these neuron
Publikováno v:
Brain research bulletin. 39(1)
The present study was undertaken to investigate the phenotypic expression and integration of human striatal neurons transplanted into an animal model of Huntington's disease. Sprague-Dawley rats were anesthetized and subjected to quinolinic acid lesi
Publikováno v:
Brain research. 695(1)
Investigations on xenografting in the brain have previously focused on the anatomical and functional integration of the transplanted neurons. More recently, astrocytes are being implicated as having complex functions following transplantation, and ar
Publikováno v:
Neuroscience research. 21(3)
Neuronal transplantation is an approach that can be exploited to study the development of the human central nervous system as well as being used in attempts to restore neurological function. In the present study, we have examined cellular events that
Publikováno v:
Experimental neurology. 121(1)
Dopaminergic projections to the caudate putamen (CPu) involve fibers in the nigrostriatal pathway from the ipsilateral substantia nigra-pars compacta. Postsynaptic receptor populations on cells receiving this information are composed of both D1 and D
Publikováno v:
Brain research bulletin. 32(2)
The localization of alpha 2-receptors was determined by quantitative autoradiography using [125I]para-iodoclonidine ([125I]PIC) and [3H]para-aminoclonidine ([3H]PAC). In cortical tissue, [125I]PIC and [3H]PAC were equipotent in their capacity to bind