Zobrazeno 1 - 10
of 99
pro vyhledávání: '"Lisa L. Liu"'
Publikováno v:
OncoImmunology, Vol 13, Iss 1 (2024)
Immune checkpoint inhibitors (ICIs) are linked to diverse immune-related adverse events (irAEs). Rare irAEs surface first in clinical practice. Here, we systematically studied the rare irAE, cytokine-release syndrome (CRS), in a cohort of 2672 patien
Externí odkaz:
https://doaj.org/article/5cab0418eaad40258e729c18bff27183
Autor:
Jodie P. Goodridge, Benedikt Jacobs, Michelle L. Saetersmoen, Dennis Clement, Quirin Hammer, Trevor Clancy, Ellen Skarpen, Andreas Brech, Johannes Landskron, Christian Grimm, Aline Pfefferle, Leonardo Meza-Zepeda, Susanne Lorenz, Merete Thune Wiiger, William E. Louch, Eivind Heggernes Ask, Lisa L. Liu, Vincent Yi Sheng Oei, Una Kjällquist, Sten Linnarsson, Sandip Patel, Kjetil Taskén, Harald Stenmark, Karl-Johan Malmberg
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Natural killer (NK) cells are functionally calibrated against self MHC during a process termed education. Here the authors show that NK cell education is associated with the accumulation of dense-core secretory lysosomes for expedited release of gran
Externí odkaz:
https://doaj.org/article/05087ace24334bc9a23a8959b77fbf46
Autor:
Lisa L. Liu, Johannes Landskron, Eivind H. Ask, Monika Enqvist, Ebba Sohlberg, James A. Traherne, Quirin Hammer, Jodie P. Goodridge, Stella Larsson, Jyothi Jayaraman, Vincent Y.S. Oei, Marie Schaffer, Kjetil Taskén, Hans-Gustaf Ljunggren, Chiara Romagnani, John Trowsdale, Karl-Johan Malmberg, Vivien Béziat
Publikováno v:
Cell Reports, Vol 15, Iss 5, Pp 1088-1099 (2016)
Infection by human cytomegalovirus (HCMV) leads to NKG2C-driven expansion of adaptive natural killer (NK) cells, contributing to host defense. However, approximately 4% of all humans carry a homozygous deletion of the gene that encodes NKG2C (NKG2C
Externí odkaz:
https://doaj.org/article/5002e9892cb84ff6933639bbd88d5d61
Autor:
Karl-Johan Malmberg, Dan Grandér, Mats Heyman, Stefan Söderhäll, Eva Hellström-Lindberg, Sören Lehmann, Marie Schaffer, Aline Pfefferle, Vincent Y.S. Oei, Vivien Béziat, Lisa L. Liu
Supplementary Figure 1. Expansion of adaptive NK cells from C1/C2 donors depends on original imprint. Supplemental Figure 2. Selective expansion of NKG2C NKG2A- NK cells depends on stimulation with HLA-E expressing feeder cells. Supplementary Figure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::216049a668caac6b4b504c63f6948132
https://doi.org/10.1158/2326-6066.22540033.v1
https://doi.org/10.1158/2326-6066.22540033.v1
Autor:
Karl-Johan Malmberg, Dan Grandér, Mats Heyman, Stefan Söderhäll, Eva Hellström-Lindberg, Sören Lehmann, Marie Schaffer, Aline Pfefferle, Vincent Y.S. Oei, Vivien Béziat, Lisa L. Liu
Manipulation of human natural killer (NK) cell repertoires promises more effective strategies for NK cell–based cancer immunotherapy. A subset of highly differentiated NK cells, termed adaptive NK cells, expands naturally in vivo in response to hum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e899b2b08a1b3bedec17c9dbaf92baa
https://doi.org/10.1158/2326-6066.c.6549259
https://doi.org/10.1158/2326-6066.c.6549259
Autor:
Karl-Johan Malmberg, Hans-Gustaf Ljunggren, Eva Hellström-Lindberg, Per Ljungman, Lotta Hansson, Marzia Palma, Björn Engelbrekt Wahlin, Pontus Blomberg, Kristina Wikström, Emma Watz, Marie Schaffer, Monika Klimkowska, Jeffrey S. Miller, Sarah Cooley, Mohsen Karimi, Trevor Clancy, Lisa L. Liu, Ebba Sohlberg, Mattias Carlsten, Andreas T. Björklund
Supplementary Figures and Tables Supplemental Figure 1. Persistence of donor NK cells in vivo. (A) Frequency of patients with detectable donor NK cells in peripheral blood (PB) at day (d)7 and/or 14 after NK cell infusion in nonresponders (NR) and re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d179003f025392a7c5d482cd8d16578
https://doi.org/10.1158/1078-0432.22469262
https://doi.org/10.1158/1078-0432.22469262
Autor:
Karl-Johan Malmberg, Hans-Gustaf Ljunggren, Eva Hellström-Lindberg, Per Ljungman, Lotta Hansson, Marzia Palma, Björn Engelbrekt Wahlin, Pontus Blomberg, Kristina Wikström, Emma Watz, Marie Schaffer, Monika Klimkowska, Jeffrey S. Miller, Sarah Cooley, Mohsen Karimi, Trevor Clancy, Lisa L. Liu, Ebba Sohlberg, Mattias Carlsten, Andreas T. Björklund
Purpose: To evaluate the safety, efficacy, and immunobiological correlates of allogeneic NK-cell–based therapy in primary chemotherapy-refractory or relapsed high-risk myelodysplastic syndrome (MDS), secondary AML (MDS/AML), and de novo AML patient
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2afafb1e9755b59f9082ad61f64c8c2f
https://doi.org/10.1158/1078-0432.c.6527187
https://doi.org/10.1158/1078-0432.c.6527187
Autor:
Per Fransson, Beatrice Ginman, Helena Ullgren, Simon Pahnke, Sumy Rosas, Gunilla Enblad, Lisa L. Liu, Signe Friesland, Ingrid Glimelius, Angela Camuto
Introduction: Cancer patients are considered to have a higher risk of dying and developing severe Coronavirus Disease 2019 (COVID-19). To date, there are few studies including co-morbidities and sociodemographic factors when investigating the outcome
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::024b9343dc0cf6f8dd54a58769c4bb18
Autor:
Jing Wu, Ying Yang, Yi Chen, Karin Larsson, Evren Alici, Hao Shi, Kai Wang, Dhifaf Sarhan, Shi Y Neo, Yumeng Mao, Andreas Lundqvist, Ziqing Chen, Lisa L. Liu, Arnika Kathleen Wagner, Per-Johan Jakobsson, Le Tong, Yihai Cao
Inadequate persistence of tumor-infiltrating natural killer (NK) cells is associated with poor prognosis in cancer patients. The solid tumor microenvironment is characterized by the presence of immunosuppressive factors, including prostaglandin E2 (P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2e4f920a02c573cd6bb747f767b2423
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-450007
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-450007
Autor:
Ziqing, Chen, Ying, Yang, Shi Y, Neo, Hao, Shi, Yi, Chen, Arnika K, Wagner, Karin, Larsson, Le, Tong, Per-Johan, Jakobsson, Evren, Alici, Jing, Wu, Yihai, Cao, Kai, Wang, Lisa L, Liu, Yumeng, Mao, Dhifaf, Sarhan, Andreas, Lundqvist
Publikováno v:
EMBO Reports
Inadequate persistence of tumor‐infiltrating natural killer (NK) cells is associated with poor prognosis in cancer patients. The solid tumor microenvironment is characterized by the presence of immunosuppressive factors, including prostaglandin E2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8a67beffd739bba0dabb71f350462a48
https://pubmed.ncbi.nlm.nih.gov/33480074
https://pubmed.ncbi.nlm.nih.gov/33480074