Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Lisa L Drewry"'
Publikováno v:
PLoS Pathogens, Vol 13, Iss 5, p e1006379 (2017)
Toxoplasma gondii contains an expanded number of calmodulin (CaM)-like proteins whose functions are poorly understood. Using a combination of CRISPR/Cas9-mediated gene editing and a plant-like auxin-induced degron (AID) system, we examined the roles
Externí odkaz:
https://doaj.org/article/fe4c32b1576e4fcabba4f572aa73a7cc
Autor:
Lisa L. Drewry, John T. Harty
Publikováno v:
Virulence, Vol 11, Iss 1, Pp 159-169 (2020)
Malarial disease caused by Plasmodium parasites challenges the mammalian immune system with a delicate balancing act. Robust inflammatory responses are required to control parasite replication within red blood cells, which if unchecked, can lead to s
Externí odkaz:
https://doaj.org/article/ed25f218519843fb8eeb1e97a0716ef7
Publikováno v:
The Journal of Immunology. 210:1305-1313
Production of IFN-γ by CD4 T cells is widely theorized to control Plasmodium parasite burden during blood-stage malaria. Surprisingly, the specific and crucial mechanisms through which this highly pleiotropic cytokine acts to confer protection again
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b1d1e60db1b059d22886913fea31d3da
https://doi.org/10.4049/jimmunol.2200899
https://doi.org/10.4049/jimmunol.2200899
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
Apicomplexan parasites such as Toxoplasma gondii possess a tubulin-rich structure called the conoid. Here, Long et al. identify a conoid protein that interacts with motor and structural proteins and is required for structural integrity of the conoid,
Externí odkaz:
https://doaj.org/article/33465d3f02bd4bd9a33944962a813a84
Autor:
Lisa L. Drewry, L. David Sibley
Publikováno v:
mBio, Vol 6, Iss 3 (2015)
ABSTRACT Apicomplexan parasites actively invade host cells using a mechanism predicted to be powered by a parasite actin-dependent myosin motor. In the model apicomplexan Toxoplasma gondii, inducible knockout of the actin gene, ACT1, was recently dem
Externí odkaz:
https://doaj.org/article/9d5e63ea242d4877a289a3f8d2bfba98
Autor:
Lisa L Drewry, John T. Harty, Mitchell N. Lefebvre, Arturo Reyes-Sandoval, Lisa S. Hancox, Lecia L. Pewe
Publikováno v:
J Immunol
Radiation-attenuated sporozoite (RAS) vaccination offers hope for global malaria control through induction of protective liver-stage–specific memory CD8 T cells. Effective RAS vaccination regimens exist; however, widespread implementation remains u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c6eb784c004ff43f09d63e108505092
https://pubmed.ncbi.nlm.nih.gov/34716185
https://pubmed.ncbi.nlm.nih.gov/34716185
Autor:
Lisa L. Drewry, John T. Harty
Publikováno v:
Trends in Parasitology. 36:651-653
Malaria is a global health scourge for which a highly effective vaccine remains frustratingly elusive. Recent identification of an endogenous malaria antigen that stimulates robust TRM-mediated immunity in mice by Valencia-Hernandez et al. strengthen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7362b61702ca284793e7fa167bb21772
https://doi.org/10.1016/j.pt.2020.06.001
https://doi.org/10.1016/j.pt.2020.06.001
Autor:
L. David Sibley, Lisa L. Drewry, Michael D. Onken, Mark J. Miller, Nathaniel G. Jones, Quiling Wang
Publikováno v:
Nature microbiology
The protozoan parasite Toxoplasma gondii is thought to exploit monocyte trafficking to facilitate dissemination across endothelial barriers such as the blood–brain barrier. Here, we analysed the migration of parasitized monocytes in model endotheli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec0e898768913a37e364d971c6aa2f31
https://doi.org/10.1038/s41564-019-0504-8
https://doi.org/10.1038/s41564-019-0504-8
Publikováno v:
The EMBO journal
Research into post‐transcriptional control of mRNAs by small noncoding RNAs (sRNAs) in the model bacteria Escherichia coli and Salmonella enterica has mainly focused on sRNAs that associate with the RNA chaperone Hfq. However, the recent discovery
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0502440c5e1dd0ff1e72708ec5fd5f5
https://hdl.handle.net/10033/621490
https://hdl.handle.net/10033/621490
Publikováno v:
The EMBO Journal
Research into post‐transcriptional control of mRNAs by small noncoding RNAs (sRNAs) in the model bacteria Escherichia coli and Salmonella enterica has mainly focused on sRNAs that associate with the RNA chaperone Hfq. However, the recent discovery
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3151baab546a235eca18b9e6a949a49f
https://pubmed.ncbi.nlm.nih.gov/28336682
https://pubmed.ncbi.nlm.nih.gov/28336682