Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Lisa Kolano"'
Publikováno v:
Frontiers in Chemistry, Vol 10 (2022)
The antimicrobial peptide (AMP) ARV-1502 was designed based on naturally occurring short proline-rich AMPs, including pyrrhocoricin and drosocin. Identification of chaperone DnaK as a therapeutic target in Escherichia coli triggered intense research
Externí odkaz:
https://doaj.org/article/956eab2cc0d5433ab9bb234051d62ae7
Publikováno v:
Chembiochem
Proline‐rich antimicrobial peptides expressed in insects are primarily active against Enterobacteriaceae. Mechanistically, they target the bacterial (70S) ribosome after partially transporter‐based cellular uptake, as revealed for Api137 and Onc1
Publikováno v:
Chembiochem : a European journal of chemical biology. 23(5)
Proline-rich antimicrobial peptides (PrAMPs) are promising candidates for the treatment of infections caused by high-priority human pathogens. Their mode of action consists of (I) passive diffusion across the outer membrane, (II) active transport thr
Publikováno v:
Frontiers in Chemistry, Vol 10 (2022)
The antimicrobial peptide (AMP) ARV-1502 was designed based on naturally occurring short proline-rich AMPs, including pyrrhocoricin and drosocin. Identification of chaperone DnaK as a therapeutic target in Escherichia coli triggered intense research
Autor:
Ines Gockel, Finn K. Hansen, Stefan R. Fritzsche, Maik Icker, Daniela Volke, Laura Sinatra, Ralf Hoffmann, Lisa Kolano, René Thieme
Publikováno v:
ChemPlusChem. 86(6)
α-Aminoxy peptides represent an interesting group of peptidomimetics with high proteolytic stability and the ability to fold into specific, predictable secondary structures. Here, we present a series of hybrid peptides consisting of α-aminoxy acids