Výsledky vyhledávání - "Lisa Koetzner"

Akademický článek

Extract2Chip—Bypassing Protein Purification in Drug Discovery Using Surface Plasmon Resonance

Autor: Ana C. F. Paiva, Ana R. Lemos, Philipp Busse, Madalena T. Martins, Diana O. Silva, Micael C. Freitas, Sandra P. Santos, Filipe Freire, Evelyne J. Barrey, Xavier Manival, Lisa Koetzner, Timo Heinrich, Ansgar Wegener, Ulrich Grädler, Tiago M. Bandeiras, Daniel Schwarz, Pedro M. F. Sousa

Publikováno v: Biosensors, Vol 13, Iss 10, p 913 (2023)

Modern drug discovery relies on combinatorial screening campaigns to find drug molecules targeting specific disease-associated proteins. The success of such campaigns often relies on functional and structural information of the selected therapeutic t

Externí odkaz: https://doaj.org/article/d755438242ab41aeaf008148835312d7

Zobrazit plný text záznamu

ChemInform Abstract: The Organocatalytic Approach to Enantiopure 2H- and 3H-Pyrroles: Inhibitors of the Hedgehog Signaling Pathway

Autor: Lisa Koetzner, Walter Thiel, Benjamin List, Sumersing Patil, Yiying Zheng, Herbert Waldmann, Sonja Sievers, Markus Leutzsch

Publikováno v: ChemInform. 47

The divergent approach to enantioenriched 2H- and 3H-pyrroles makes use of a Fischer-type indolization and a subsequent [1,5]-alkyl shift.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f6a362bcaf8e477fe2881b3dbf687764
https://doi.org/10.1002/chin.201645120

Zobrazit plný text záznamu

ChemInform Abstract: Catalytic Asymmetric Dearomatizing Redox Cross Coupling of Ketones with Aryl Hydrazines Giving 1,4-Diketones

Autor: Shenlin Huang, Chandra Kanta De, Lisa Koetzner, Benjamin List

Publikováno v: ChemInform. 46

1,4-Diketones bearing an all-carbon quarternary stereocenter are synthesized via asymmetric dearomatizing redox cross-coupling reaction between aryl hydrazines and cyclic ketones in the presence of a SPINOL-derived phosphoric acid as chiral catalyst.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c7861ee50daa30c4c790dad919428ecc
https://doi.org/10.1002/chin.201534064

Zobrazit plný text záznamu

ChemInform Abstract: Asymmetric Catalysis on the Nanoscale: The Organocatalytic Approach to Helicenes

Autor: Matthew J. Webber, Claudia De Fusco, Lisa Koetzner, Benjamin List, Alberto Martínez

Publikováno v: ChemInform. 45

The first asymmetric synthesis of chiral helicenes catalyzed by a novel phosphoric acid via the Fischer indole reaction is reported.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f89e2aef69299cd97ec3ce281a9f5824
https://doi.org/10.1002/chin.201440132

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání