Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Lisa Kockeritz"'
Autor:
Natasza A Kurpios, Adele Girgis-Gabardo, Robin M Hallett, Stephen Rogers, David W Gludish, Lisa Kockeritz, James Woodgett, Robert Cardiff, John A Hassell
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e58151 (2013)
The tumor-initiating cell (TIC) frequency of bulk tumor cell populations is one of the criteria used to distinguish malignancies that follow the cancer stem cell model from those that do not. However, tumor-initiating cell frequencies may be influenc
Externí odkaz:
https://doaj.org/article/70d30803d5c14f6c903339ecc6b17fc7
Autor:
Tommy Noh, Yankel Gabet, Jon Cogan, Yunfan Shi, Archana Tank, Tomoyo Sasaki, Braden Criswell, Alexis Dixon, Christopher Lee, Joseph Tam, Thomas Kohler, Eran Segev, Lisa Kockeritz, James Woodgett, Ralph Müller, Yang Chai, Elisheva Smith, Itai Bab, Baruch Frenkel
Publikováno v:
PLoS ONE, Vol 4, Iss 5, p e5438 (2009)
We investigated the role of Lef1, one of the four transcription factors that transmit Wnt signaling to the genome, in the regulation of bone mass. Microcomputed tomographic analysis of 13- and 17-week-old mice revealed significantly reduced trabecula
Externí odkaz:
https://doaj.org/article/6eb67f210fce47ed908c41e79dd00a92
Publikováno v:
Current Drug Targets. 7:1377-1388
Glycogen synthase kinase-3 (GSK-3) has attracted much scrutiny due to its plethora of cellular functions, novel mechanisms of regulation and its potential as a therapeutic target for several common diseases. In mammals, GSK-3 is encoded by two genes,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b5ce8db4ad0dc073d5d78e2de7f8a92
https://doi.org/10.2174/1389450110607011377
https://doi.org/10.2174/1389450110607011377
Autor:
Lisa Kockeritz, Natasza A. Kurpios, Stephen Rogers, David W. Gludish, Adele Girgis-Gabardo, Robin M. Hallett, James R. Woodgett, Robert D. Cardiff, John A. Hassell
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e58151 (2013)
PLoS ONE
PloS one, vol 8, iss 3
PLoS ONE
PloS one, vol 8, iss 3
The tumor-initiating cell (TIC) frequency of bulk tumor cell populations is one of the criteria used to distinguish malignancies that follow the cancer stem cell model from those that do not. However, tumor-initiating cell frequencies may be influenc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d28d884d80743239f63d6c44b3668927
http://europepmc.org/articles/PMC3608640?pdf=render
http://europepmc.org/articles/PMC3608640?pdf=render
Autor:
Tomoyo Sasaki, Yang Chai, Braden Criswell, Eran Segev, Archana Tank, Yunfan Shi, Baruch Frenkel, Ralph Müller, Joseph Tam, Christopher Lee, Yankel Gabet, Thomas Kohler, Itai Bab, Tommy Noh, Jon Cogan, Elisheva Smith, James R. Woodgett, Lisa Kockeritz, Alexis Dixon
Publikováno v:
PLoS ONE
PLoS ONE, Vol 4, Iss 5, p e5438 (2009)
PLoS ONE, 4 (5)
PLoS ONE, Vol 4, Iss 5, p e5438 (2009)
PLoS ONE, 4 (5)
We investigated the role of Lef1, one of the four transcription factors that transmit Wnt signaling to the genome, in the regulation of bone mass. Microcomputed tomographic analysis of 13- and 17-week-old mice revealed significantly reduced trabecula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f8080ea8dac912da5a3952dd61e2ec3
http://europepmc.org/articles/PMC2673053
http://europepmc.org/articles/PMC2673053
Autor:
Bradley W. Doble, James R. Woodgett, Kathleen C. Woulfe, Thomas Force, Jonathan A. Epstein, Risto Kerkelä, Sarah Greytak, Jibin Zhou, Katrina MacAulay, Lisa Kockeritz, Cara Beahm, Gordon S. Huggins, Chinmay M. Trivedi
Based on extensive preclinical data, glycogen synthase kinase-3 (GSK-3) has been proposed to be a viable drug target for a wide variety of disease states, ranging from diabetes to bipolar disorder. Since these new drugs, which will be more powerful G
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6da305963d811e9887932e2a63570b1f
https://europepmc.org/articles/PMC2556242/
https://europepmc.org/articles/PMC2556242/
Autor:
Raul R. Gainetdinov, Lisa Kockeritz, Jean-Martin Beaulieu, Wei-Dong Yao, Marc G. Caron, James R. Woodgett, Tatyana D. Sotnikova
Dopamine (DA) is a neurotransmitter involved in the control of locomotion, emotion, cognition, and reward. Administration of lithium salts is known to inhibit DA-associated behaviors in experimental animal models through unknown mechanisms. Here, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7526183ce218a886a75e400410dc9ca6
https://europepmc.org/articles/PMC387380/
https://europepmc.org/articles/PMC387380/
Publikováno v:
Current biology : CB. 11(22)
Background: The PEA3 Ets transcription factor is overexpressed in the vast majority of human breast tumors and in nearly all of those of the HER2/Neu-positive subclass. PEA3 is also overexpressed in various transgenic mouse models of this disease. Wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e82631c60133bd606c9bd2f551b8996
https://pubmed.ncbi.nlm.nih.gov/11719215
https://pubmed.ncbi.nlm.nih.gov/11719215
Autor:
Tommy Noh, Joseph Tam, Braiden Criswell, Lisa Kockeritz, Elisheva Smith, Baruch Frenkel, Jon Cogan, James R. Woodgett, Thomas Kohler, Alexis Dixon, Archana Tank, Yankel Gabet, Itai Bab, Ralph Müller, Eran Regev, Tomoyo Sasaki, Yang Chai
Publikováno v:
Bone. 42:S50
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3feead7a36ea250f2cdcfa0c87f62728
https://doi.org/10.1016/j.bone.2007.12.085
https://doi.org/10.1016/j.bone.2007.12.085
Publikováno v:
Developmental Cell. (6):957-971
In mammalian cells, glycogen synthase kinase-3 (GSK-3) exists as two homologs, GSK-3alpha and GSK-3beta, encoded by independent genes, which share similar kinase domains but differ substantially in their termini. Here, we describe the generation of a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea22c4a48ea30f5156a46ce3a823778f