Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Lisa Kirouac"'
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e57979 (2013)
Altered proteolysis of amyloid precursor protein is an important determinant of pathology development in Alzheimer's disease. Here, we describe the detection of two novel fragments of amyloid precursor protein in H4 neuroglioma cells undergoing apopt
Externí odkaz:
https://doaj.org/article/24cc2708da8a4c0d89fc194f3a8472c6
Publikováno v:
Oncotarget
Amyloid Precursor Protein (APP) is regulated in a mitosis-specific manner and plays a role in proliferative signaling in cells. Though APP-derived Aβ generation has a well-established role in neurodegeneration, the mechanistic role of APP in this pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fed1d4cd70592983410ab0a8043dac4
https://doi.org/10.18632/oncotarget.7380
https://doi.org/10.18632/oncotarget.7380
Publikováno v:
The FASEB Journal. 34:1-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5a5cf81f0a561f10a774350846afccaf
https://doi.org/10.1096/fasebj.2020.34.s1.09481
https://doi.org/10.1096/fasebj.2020.34.s1.09481
Publikováno v:
eNeuro
It is widely accepted that amyloid β (Aβ) generated from amyloid precursor protein (APP) oligomerizes and fibrillizes to form neuritic plaques in Alzheimer’s disease (AD), yet little is known about the contribution of APP to intracellular signali
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aca9fb7f4c8c902a5975e25775635951
http://europepmc.org/articles/PMC5367084
http://europepmc.org/articles/PMC5367084
Autor:
Jaya Padmanabhan, Umesh K. Jinwal, Stanley M. Stevens, Dale Chaput, Lisa Kirouac, Malathi Narayan
Publikováno v:
Journal of Data Mining in Genomics & Proteomics.
Alzheimer’s disease (AD) is the most common form of dementia and the 6th leading cause of death in the United States. The major pathological hallmarks observed in AD include the formation of intracellular neurofibrillary tangles comprised of phosph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0f1444a498e5d26bc52af87130d863e0
https://doi.org/10.4172/2153-0602.1000193
https://doi.org/10.4172/2153-0602.1000193
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e57979 (2013)
PLoS ONE
PLoS ONE
Altered proteolysis of amyloid precursor protein is an important determinant of pathology development in Alzheimer's disease. Here, we describe the detection of two novel fragments of amyloid precursor protein in H4 neuroglioma cells undergoing apopt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfede90a07530d94e8ee94298153e074
https://doi.org/10.1371/journal.pone.0057979
https://doi.org/10.1371/journal.pone.0057979