Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Lisa Kifinger"'
Autor:
Kai P. Hoefig, Alexander Reim, Christian Gallus, Elaine H. Wong, Gesine Behrens, Christine Conrad, Meng Xu, Lisa Kifinger, Taku Ito-Kureha, Kyra A. Y. Defourny, Arie Geerlof, Josef Mautner, Stefanie M. Hauck, Dirk Baumjohann, Regina Feederle, Matthias Mann, Michael Wierer, Elke Glasmacher, Vigo Heissmeyer
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
An extensive RNA binding protein atlas (RBPome) for primary T cells would be a useful resource. Here the authors use two different methods to characterise the mouse and human T cell RBPome and show regulation of Roquin-1/2 dependent and independent p
Externí odkaz:
https://doaj.org/article/79f61fbb2db9463391f56fc5ab732e2e
Disrupting Roquin-1 interaction with Regnase-1 induces autoimmunity and enhances antitumor responses
Autor:
Stephanie L. Edelmann, Laura S. de Jonge, Lisa Kifinger, Wolfgang Wurst, Florian Giesert, Christine Hohn, Naoto Kawakami, Sebastian Theurich, Mingui Fu, Dierk Niessing, Nina Kronbeck, Martin E. Kirmaier, Vigo Heissmeyer, Timsse Raj, Thomas Monecke, Elena S. Davydova, Elaine H. Wong, Stefan Feske, Gesine Behrens, Mariano Gonzalez Pisfil
Publikováno v:
Nat Immunol
Nat. Immunol. 22, 1563-1576 (2021)
Nature immunology 22(12), 1563-1576 (2021). doi:10.1038/s41590-021-01064-3
Nat. Immunol. 22, 1563-1576 (2021)
Nature immunology 22(12), 1563-1576 (2021). doi:10.1038/s41590-021-01064-3
Roquin and Regnase-1 proteins bind and post-transcriptionally regulate proinflammatory target messenger RNAs to maintain immune homeostasis. Either the sanroque mutation in Roquin-1 or loss of Regnase-1 cause systemic lupus erythematosus-like phenoty
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c47294afa473dd395ea8a5b1a5695f3
https://europepmc.org/articles/PMC8996344/
https://europepmc.org/articles/PMC8996344/