Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Lisa K. Kreppel"'
Autor:
Lisa K. Kreppel, Gerald W. Hart
Publikováno v:
Journal of Biological Chemistry. 274:32015-32022
The O-GlcNAc transferase (OGT) is a unique nuclear and cytosolic glycosyltransferase that contains multiple tetratricopeptide repeats. We have begun to characterize the mechanisms regulating OGT using a combination of deletion analysis and kinetic st
Autor:
Toshiyuki MATSUZAKI, Takeshi SUZUKI, Kuniaki TAKATA, Shin HASHIGUCHI, Masazumi HIRATA, Hiroaki MURATA, Hideyuki TAKESHITA, Katsuyuki KUSUZAKI, Eiichi KONISHI, Yasusuke HIRASAWA, Tsukasa ASHIHARA, T. Suginoshita, K. Kusuzaki, S. Hashiguchi, M. Hirata, J. Fukuroku, Y. Urata, Y. Hirasawa, T. Ashihara, Kanji KAWAI, Kazushige UEDA, Toshiya OCHIAI, Atsuhiro OGINO, Hirosumi ITOI, Hisakazu YAMAGISHI, Yoji URATA, Takahiro OKA, Toshiaki YAMAASHI, Masahiko AKITA, Ken TANOOKA, Kojun SETSU, Yasuhisa Maezawa, Hisatoshi Baba, Nobuaki Furusawa, Kenzou Uchida, Shinichi Imura, Yoshitaka TAMADA, Seiji HAYASHI, Norio IIJIMA, Hiromi IKE, Akihiko ISHIHARA, Masaki TANAKA, Fumihiko SUWA, Yasuhiko IBATA, Masaru Kimura, Hiroyasu SUGA, Norio MIYOSI, Takao NAKAGAWA, Masaru FUKUDA, Vadim S. Zinchuk, Teruhiko Okada, Toshihiro Kobayashi, Eva Garcia del Saz, Harumichi Seguchi, Youyun Zhang, Jibin Dai, Xinhua Zhou, Fong Dong, Akihiro HEMMI, Akira KOMIYAMA, Shinichi OHNO, Ryohei KATOH, Hideyuki Takeshita, Katsuyuki Kusuzaki, Yoshiro Tsuji, Masazumi Hirata, Shin Hashiguchi, Yasusuke Hirasawa, Tsukasa Ashihara, Shigeru MORIKAWA, Ikuko TORII, Makoto NAGASAKI, Satoko MISHIMA, Akira Mizoguchi, Chizuka Ide, Ichiro NAITO, Satoko INOUE, Satimaru SENO, Jun WATANABE, Kazumasa KONDO, Kazuto Mino, Shinsuke KANAMURA, Kohsuke CHIDA, Tetusya GOTO, Teruo TANAKA, Shigeru TAKAMI, Tatsuroh ODA, Fumiaki NISHIYAMA, Tomohiko Wakayama, Shoichi Iseki, AHMED KHALED, S. NORIKI, H. MAEGAWA, M. FUKUDA, Mingsen Jiang, Zujiang Yu, Mingyi Yang, Huifen Dong, Masaki UENO, Yutaka FUTAESAKU, Yoshimichi KOZUKA, Misai YANO, Michiko ONO, Yawara SUMI, Masanori T. Itoh, Minoru YOSHIDA, Atsuko Ito, Michiko Hayashi, Minako Hoshida, Kinji Ito, Kyoumi NAKAZATO, Keiji SUZUKI, Katuyuki NAKAJIMA, Tsuyoshi SAGA, Mitsuaki YOSHIZUKA, Norimichi Nemoto, Wei Lu, Hitomi Nakamura, Satoshi Hayakawa, Fuminao Chishima, Akio WATANABA, Akira KAWAOI, Lidia KRIA, Akihiro OHIRA, Tsugio AMEMIYA, Kazuhiro KARAYA, Takashi KONDO, Shinobu UMEMURA, Masanori YASUDA, Johbu ITOH, Susumu TAKEKOSHI, Yoshiyuki OSAMURA, Keiichi WATANABE, Yukihiro SASAKI, Helen AHMED, Takumi TAKEUCHI, Tetsuo UEKI, Takahiro KAJIWARA, Nobuo MORIYAMA, Kazuki KAWABE, Hiromichi YOKOI, Yoshihiro YAMAMA, Yoshihiro TSURUO, Kazunori ISHIMURA, Yoichiro Kato, Tomoko Yamamoto, Makio Kobayashi, Shin-ichi KOMIYAMA, Daisuke AOKI, Eiichiro TOMINAGA, Nobuyuki SUSUMU, Yasuhiro UDAGAWA, Shiro NOZAWA, Hideaki MURATA, Youzi URATA, Toshihisa Ito, Kohjiro HORITA, Yoshiaki IMAMURA, Sakon NORIKI, Gizo NAKAGAWARA, Yiqun Mo, Qunwei Zhang, Akio Yamaguchi, Kohjiro Horita, Shu Zheng, Chong-Guang Leng, Hideho Ueda, Yasuhisa Fujii, Nobuo Terada, Takeshi Baba, S. Yamazaki, S. Kameyama, R. Fukasawa, N. Moriyama, K. Kawabe, Yasuhiro KOBAYASHI, Hayato KAWAKAMI, Yoshikazu YOSHINO, Hiroshi HIRANO, Yoshihiro AKIMOTO, Lisa K. KREPPEL, Gerald W. HART, Kenji KAWASHIMA, Kyomi NAKAZATO, Katsuya HIRAISHI, Katsuaki UEHARA, Junichi SHIMADA, Shinji FUSHIKI, Nobuyuki Susumu, Ryohachi ARAI, Kazuyoshi SAKAI, Ikuko NAGATSU, Bo-Chul Shin, Yoshihiro ASAKAWA, Masato KOMURO, Lanxian Zhou, Hua Yuan, Jialuo Hu, Wenduo Huang, Xiaoyun Wang, Yohei MIYAMOTO, Mari SHIMBO, Shigeyuki TAHARA, Makoto SUGIYAMA, Ichiro TAKUMI, Naoko SANNO, Akira TERAMOTO, Minoru MATSUDA, Hisaki FUKUSHIMA, Ryota TANAKA, Ikuya SANTO, Tateo HANAOKA, Tomoyuki GOYA, Akihiko KUDO, Akihiko Kudo
Publikováno v:
ACTA HISTOCHEMICA ET CYTOCHEMICA. 31:152-166
Publikováno v:
Journal of Biological Chemistry. 272:9308-9315
O-Linked N-acetylglucosamine (O-GlcNAc) glycosylation is a dynamic modification of eukaryotic nuclear and cytosolic proteins analogous to protein phosphorylation. We have cloned and characterized a novel gene for an O-GlcNAc transferase (OGT) that sh
Autor:
Bradley K. Hayes, Zhengyi Ye, Yoshihiro Akimoto, Lisa K. Kreppel, B. J. Earles, Frank I. Comer, Robert N. Cole, Xiaogang Cheng, Diane M. Snow, D. S. Caine, D. Dellamanna, Gerald W. Hart, C. S. Arnold
Publikováno v:
Glycobiology. 6:711-716
O-Linked N-acetylglucosamine, O-GlcNAc, was discovered (Torres and Hart, 1984) as part of our studies using highlypurified glycosyltransferases to investigate saccharide structures on lymphocytes and tumor cells (Powell et al, 1987; Whiteheart and Ha
Autor:
Man-shiow Jiang, Gerald W. Hart, Lisa K. Kreppel, Kenneth D. Greis, Melissa A. Blomberg, R. C. Cole, Diane M. Snow, L.-Y. D. Dong, Elizabeth P. Roquemore, Teh-Ying Chou, Bradley K. Hayes
Publikováno v:
Pure and Applied Chemistry. 67:1637-1645
Gerzrldk& K C I I I W ~ ~ 11. Greis, I,.-Y. Dermis I h g , Melissa A. Bloinherg Teh-Yirig Chou, MatiSliiow Jiatg Llizaheth I? I ~ ~ I ~ I I I ~ ~ c , loris M. Snow, Lisa K. Kreppel, Itoberl C. Cole atid Bradley K. Hayes. Dept. Biocheni. & Molecular G
Autor:
Kenneth D. Greis, R. C. Cole, Elizabeth P. Roquemore, Diane M. Snow, Lisa K. Kreppel, Melissa A. Blomberg, Bradley K. Hayes, Man-shiow Jiang, Teh-Ying Chou, Gerald W. Hart, L.-Y. D. Dong
Publikováno v:
ChemInform. 27
Gerzrldk& K C I I I W ~ ~ 11. Greis, I,.-Y. Dermis I h g , Melissa A. Bloinherg Teh-Yirig Chou, MatiSliiow Jiatg Llizaheth I? I ~ ~ I ~ I I I ~ ~ c , loris M. Snow, Lisa K. Kreppel, Itoberl C. Cole atid Bradley K. Hayes. Dept. Biocheni. & Molecular G
Autor:
Robert S. Haltiwanger, Lisa K. Kreppel, Gerald W. Hart, Melissa A. Blomberg, William G. Kelly, L.-Y. Dennis Dong, Elizabeth P. Roquemore, Teh-Ying Chou
Publikováno v:
Biochemical Society Transactions. 20:264-269
Introduction We have described a major new form of protein glycosylation (termed 0-GlcNAc) that is found in all eukaryotes from yeast to man. 0-GlcNAc is distinct from other types of protein-bound saccharides in several respects (for review see [ l ]
Publikováno v:
The Journal of biological chemistry. 279(37)
A hallmark of signal transduction is the dynamic and inducible post-translational modification of proteins. In addition to the well characterized phosphorylation of proteins, other modifications have been shown to be regulatory, including O-linked be
Publikováno v:
Archives of biochemistry and biophysics. 389(2)
Hyperglycemia leads to vascular disease specific to diabetes mellitus. This pathology, which results from abnormal proliferation of smooth muscle cells in arterial walls, may lead to cataract, renal failure, and atherosclerosis. The hexosamine biosyn
Publikováno v:
Diabetologia. 43(10)
Aims/hypothesis. Streptozotocin (STZ), a chemically reactive analogue of N-acetylglucosamine, induces necrosis of the beta cells, resulting in diabetes mellitus. Glucose-induced insulin resistance is mediated by increased activity of the hexosamine p