Zobrazeno 1 - 10
of 75
pro vyhledávání: '"Lisa K. Folkes"'
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 3, p 1797 (2022)
The widespread interest in free radicals in biology extends far beyond the effects of ionizing radiation, with recent attention largely focusing on reactions of free radicals derived from peroxynitrite (i.e., hydroxyl, nitrogen dioxide, and carbonate
Externí odkaz:
https://doaj.org/article/f0e0a83a7f3e4c179ada3b915a77250c
Autor:
Liam J. O’Connor, Ishna N. Mistry, Sarah L. Collins, Lisa K. Folkes, Graham Brown, Stuart J. Conway, Ester M. Hammond
Publikováno v:
ACS Central Science, Vol 3, Iss 1, Pp 20-30 (2016)
Externí odkaz:
https://doaj.org/article/1f5dd5db05b144d7a17a6b55a3c87d4b
Autor:
Thomas M. Ashton, Emmanouil Fokas, Leoni A. Kunz-Schughart, Lisa K. Folkes, Selvakumar Anbalagan, Melanie Huether, Catherine J. Kelly, Giacomo Pirovano, Francesca M. Buffa, Ester M. Hammond, Michael Stratford, Ruth J. Muschel, Geoff S. Higgins, William Gillies McKenna
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
Tumour hypoxia reduces the efficacy of radiotherapy. Starting from a drug screen, here the authors demonstrate that the anti-malarial, atovaquone, reduces the oxygen consumption rate of cancer cells by inhibition of mitochondrial complex III and sens
Externí odkaz:
https://doaj.org/article/5fcde319119841a9a1a9daedc3b99552
Autor:
Geoff S. Higgins, Ruth E. Macpherson, Francesca M. Buffa, Daniel Bulte, Adrian L. Harris, W. Gillies McKenna, Fergus V. Gleeson, James P.B. O’Connor, Jane Holmes, Cathy Qi, Helen Flight, Paula L. Croal, Petra Ferencz, Leticia Campo, Lisa K. Folkes, Remko Prevo, Gonzalo Rodriguez-Berriguete, Marcus Green, Joshua A. Bull, Philip S. Macklin, Benjamin H.L. Harris, Dawn O’Reilly, Jagat Chauhan, Eugene Teoh, Kwun-Ye Chu, Jennifer L. Derham, Mark McCole, Dionisios Stavroulias, Francesco Di Chiara, Elizabeth Belcher, Daniel R. McGowan, Michael Skwarski
Supplementary Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3dfeeee5036e9bf1bbf90f8c52150f61
https://doi.org/10.1158/1078-0432.22482990
https://doi.org/10.1158/1078-0432.22482990
Autor:
Geoff S. Higgins, Ruth E. Macpherson, Francesca M. Buffa, Daniel Bulte, Adrian L. Harris, W. Gillies McKenna, Fergus V. Gleeson, James P.B. O’Connor, Jane Holmes, Cathy Qi, Helen Flight, Paula L. Croal, Petra Ferencz, Leticia Campo, Lisa K. Folkes, Remko Prevo, Gonzalo Rodriguez-Berriguete, Marcus Green, Joshua A. Bull, Philip S. Macklin, Benjamin H.L. Harris, Dawn O’Reilly, Jagat Chauhan, Eugene Teoh, Kwun-Ye Chu, Jennifer L. Derham, Mark McCole, Dionisios Stavroulias, Francesco Di Chiara, Elizabeth Belcher, Daniel R. McGowan, Michael Skwarski
Purpose:Tumor hypoxia fuels an aggressive tumor phenotype and confers resistance to anticancer treatments. We conducted a clinical trial to determine whether the antimalarial drug atovaquone, a known mitochondrial inhibitor, reduces hypoxia in non–
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ee0906251ef98712c4b6555ffa3022c
https://doi.org/10.1158/1078-0432.c.6531051
https://doi.org/10.1158/1078-0432.c.6531051
Autor:
Valentine M. Macaulay, Anderson J. Ryan, Thomas Bogenrieder, Ulrike Weyer-Czernilofsky, Lisa K. Folkes, Daniel V. Ebner, Stephanie B. Hatch, Elena Seraia, Laura Colling, Ashwin Nandakumar, Jack V. Mills, Letitia E. Harris, Xiaoning Wu, Guillaume Rieunier
Supplementary methods, Table S1-S2, Figure S1-S6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59d3eeb616d9b591fa09bcffabeb8d0e
https://doi.org/10.1158/0008-5472.22430394.v1
https://doi.org/10.1158/0008-5472.22430394.v1
Autor:
Valentine M. Macaulay, Anderson J. Ryan, Thomas Bogenrieder, Ulrike Weyer-Czernilofsky, Lisa K. Folkes, Daniel V. Ebner, Stephanie B. Hatch, Elena Seraia, Laura Colling, Ashwin Nandakumar, Jack V. Mills, Letitia E. Harris, Xiaoning Wu, Guillaume Rieunier
Inhibition of IGF receptor (IGF1R) delays repair of radiation-induced DNA double-strand breaks (DSB), prompting us to investigate whether IGF1R influences endogenous DNA damage. Here we demonstrate that IGF1R inhibition generates endogenous DNA lesio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ede2d91d7d3136d5890c2227e2a28265
https://doi.org/10.1158/0008-5472.c.6513606.v1
https://doi.org/10.1158/0008-5472.c.6513606.v1
Autor:
Geoff S. Higgins, Ruth E. Macpherson, Francesca M. Buffa, Daniel Bulte, Adrian L. Harris, W. Gillies McKenna, Fergus V. Gleeson, James P.B. O’Connor, Jane Holmes, Cathy Qi, Helen Flight, Paula L. Croal, Petra Ferencz, Leticia Campo, Lisa K. Folkes, Remko Prevo, Gonzalo Rodriguez-Berriguete, Marcus Green, Joshua A. Bull, Philip S. Macklin, Benjamin H.L. Harris, Dawn O’Reilly, Jagat Chauhan, Eugene Teoh, Kwun-Ye Chu, Jennifer L. Derham, Mark McCole, Dionisios Stavroulias, Francesco Di Chiara, Elizabeth Belcher, Daniel R. McGowan, Michael Skwarski
Supplementary Figures and Tables
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e4f1eca65390f075ca2307e369d9ff0
https://doi.org/10.1158/1078-0432.22482996.v1
https://doi.org/10.1158/1078-0432.22482996.v1
Autor:
Ester M. Hammond, Adrian L. Harris, Mike R. Stratford, Ji-Liang Li, Lisa K. Folkes, Manuela Milani, Zuzana Bencokova, Isabel M. Pires
Supplementary Figure Legends 1-5 from Effects of Acute versus Chronic Hypoxia on DNA Damage Responses and Genomic Instability
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::726862ed4a6142c93e464714dcdc6084
https://doi.org/10.1158/0008-5472.22387496.v1
https://doi.org/10.1158/0008-5472.22387496.v1
Autor:
Ester M. Hammond, Adrian L. Harris, Mike R. Stratford, Ji-Liang Li, Lisa K. Folkes, Manuela Milani, Zuzana Bencokova, Isabel M. Pires
Supplementary Figures 1-5 from Effects of Acute versus Chronic Hypoxia on DNA Damage Responses and Genomic Instability
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56a35a7f0b21664f739376cb89c1d186
https://doi.org/10.1158/0008-5472.22387493.v1
https://doi.org/10.1158/0008-5472.22387493.v1