Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Lisa Kötzner"'
Publikováno v:
Acta Crystallographica Section E: Crystallographic Communications, Vol 72, Iss 2, Pp 128-132 (2016)
In the title free base porphyrin, C42H34N4, the neighbouring N...N distances in the center of the ring vary from 2.818 (8) to 2.998 (8) Å and the phenyl rings are tilted from the 24-atom mean plane at angles varying between 62.42 (2)–71.63 (2)°.
Externí odkaz:
https://doaj.org/article/69d1bde5829e48e58feddce0b5bc1ba0
Publikováno v:
Acta Crystallographica Section E: Crystallographic Communications, Vol 71, Iss 11, Pp 1397-1400 (2015)
The asymmetric unit of the title nickel(II) porphyrin, [Ni(C48H60N4O2)], contains one independent molecule. The average Ni—N bond length is 1.917 (13) Å. The molecules are arranged in a closely spaced lattice structure in which neighbouring porphy
Externí odkaz:
https://doaj.org/article/88157749a15a4742be1374ceaeffd74c
Autor:
Timo Heinrich, Carl Peterson, Richard Schneider, Sakshi Garg, Daniel Schwarz, Jakub Gunera, Anita Seshire, Lisa Kötzner, Sarah Schlesiger, Djordje Musil, Heike Schilke, Benjamin Doerfel, Patrizia Diehl, Pia Böpple, Ana R. Lemos, Pedro M. F. Sousa, Filipe Freire, Tiago M. Bandeiras, Emma Carswell, Nicholas Pearson, Sameer Sirohi, Mollie Hooker, Elisabeth Trivier, Rebecca Broome, Alexander Balsiger, Abigail Crowden, Christian Dillon, Dirk Wienke
Publikováno v:
Journal of Medicinal Chemistry. 65:9206-9229
Publikováno v:
Nature reviews. Drug discovery. 21(11)
The advent of immune checkpoint inhibition (ICI) using antibodies against PD1 and its ligand PDL1 has prompted substantial efforts to develop complementary drugs. Although many of these are antibodies directed against additional checkpoint proteins,
Publikováno v:
Progress in medicinal chemistry. 59
Immuno-oncology therapies are revolutionizing the oncology landscape with checkpoint blockade becoming the treatment backbone for many indications. While inspiring, much work remains to increase the number of cancer patients that can benefit from the
Immuno-oncology therapies are revolutionizing the oncology landscape with checkpoint blockade becoming the treatment backbone for many indications. While inspiring, much work remains to increase the number of cancer patients that can benefit from the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f0309c749df2c83fff3e7d3758a7eab1
https://doi.org/10.1016/bs.pmch.2019.11.001
https://doi.org/10.1016/bs.pmch.2019.11.001
Publikováno v:
Angewandte Chemie (International Ed. in English)
Immuno‐oncology therapies have the potential to revolutionize the armamentarium of available cancer treatments. To further improve clinical response rates, researchers are looking for novel combination regimens, with checkpoint blockade being used
Publikováno v:
Angewandte Chemie. 130:4499-4516
Autor:
Yiying Zheng, Lisa Kötzner, Sumersing Patil, Sonja Sievers, Markus Leutzsch, Herbert Waldmann, Benjamin List, Walter Thiel
Publikováno v:
Angewandte Chemie. 128:7824-7828
Publikováno v:
Acta Crystallographica Section E: Crystallographic Communications, Vol 71, Iss 11, Pp 1397-1400 (2015)
Acta Crystallographica Section E: Crystallographic Communications
Acta Crystallographica Section E: Crystallographic Communications
The title compound contains one independent molecule which exhibits an overall ruffled conformation, with an average Ni—N bond length of 1.917 (13) Å. The molecules form a closely spaced lattice structure in which neighbouring porphyrins are o